Inhibition of ALK5 signaling induces physeal dysplasia in rats (Q33279063)

25 July 2017

Inhibition of ALK5 signaling induces physeal dysplasia in rats (English)

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25 July 2017

Kendall Frazier

1

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25 July 2017

Roberta Thomas

2

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25 July 2017

Marshall Scicchitano

3

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25 July 2017

Rosanna Mirabile

4

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25 July 2017

Rogely Boyce

5

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25 July 2017

Dawn Zimmerman

6

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25 July 2017

Eugene Grygielko

7

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25 July 2017

James Nold

8

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25 July 2017

Anne-Charlotte DeGouville

9

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25 July 2017

Stephane Huet

10

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25 July 2017

Nicholas Laping

11

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25 July 2017

Francoise Gellibert

12

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25 July 2017

language of work or name

English

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publication date

1 February 2007

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25 July 2017

Toxicologic Pathology

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25 July 2017

35

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25 July 2017

2

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25 July 2017

284-295

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Parathyroid hormone-related peptide-depleted mice show abnormal epiphyseal cartilage development and altered endochondral bone formation

25 July 2017

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

Cytokine control of interstitial collagenase and collagenase-3 gene expression in human chondrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

Cartilage dysplasia and tissue mineralization in the rat following administration of a FGF receptor tyrosine kinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

Identification of novel inhibitors of the transforming growth factor beta1 (TGF-beta1) type 1 receptor (ALK5).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

FGF and VEGF function in angiogenesis: signalling pathways, biological responses and therapeutic inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

Targeted disruption of Smad3 reveals an essential role in transforming growth factor beta-mediated signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

Metabolic mapping of proteinase activity with emphasis on in situ zymography of gelatinases: review and protocols

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

Bone morphogenetic protein-7 in growth-plate chondrocytes: regulation by retinoic acid is dependent on the stage of chondrocyte maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

Inhibition of gene markers of fibrosis with a novel inhibitor of transforming growth factor-beta type I receptor kinase in puromycin-induced nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

Fibrates induce hepatic peroxisome and mitochondrial proliferation without overt evidence of cellular proliferation and oxidative stress in cynomolgus monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

Analysis of connective tissues by laser capture microdissection and reverse transcriptase-polymerase chain reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

Analysis of osteopontin in mouse growth plate cartilage by application of laser capture microdissection and RT-PCR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

ALK5 inhibition in renal disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

Inhibition of transforming growth factor (TGF)-beta1-induced extracellular matrix with a novel inhibitor of the TGF-beta type I receptor kinase activity: SB-431542

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

Effects of parathyroid hormone-related peptide on chick growth plate chondrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

Production of extracellular matrix by glomerular epithelial cells is regulated by transforming growth factor-beta 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

Hypertensive target organ damage is attenuated by a p38 MAPK inhibitor: role of systemic blood pressure and endothelial protection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

How proteases regulate bone morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

Preclinical safety evaluation of rhuMAbVEGF, an antiangiogenic humanized monoclonal antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

Expression of a truncated, kinase-defective TGF-beta type II receptor in mouse skeletal tissue promotes terminal chondrocyte differentiation and osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

Parathyroid hormone-related peptide (PTHrP)-dependent and -independent effects of transforming growth factor beta (TGF-beta) on endochondral bone formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

Altered endochondral bone development in matrix metalloproteinase 13-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

Bone morphogenetic proteins and bFGF exert opposing regulatory effects on PTHrP expression and inorganic pyrophosphate elaboration in immortalized murine endochondral hypertrophic chondrocytes (MCT cells).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

Collagenase-3 (MMP-13) expression in chondrosarcoma cells and its regulation by basic fibroblast growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

Differential effects of transforming growth factor-beta on the expression of collagenase-1 and collagenase-3 in human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

Systemic and local regulation of the growth plate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

Proteolysis involving matrix metalloproteinase 13 (collagenase-3) is required for chondrocyte differentiation that is associated with matrix mineralization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

TGF-beta/Smad3 signals repress chondrocyte hypertrophic differentiation and are required for maintaining articular cartilage

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

Distinct Phases of Coordinated Early and Late Gene Expression in Growth Plate Chondrocytes in Relationship to Cell Proliferation, Matrix Assembly, Remodeling, and Cell Differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230701198469

10.1080/01926230701198469

21 January 2018

Identifiers

DOI

1 reference

25 July 2017

1 reference