Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1. (Q33293671)

25 July 2017

Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1. (English)

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25 July 2017

Titia de Lange

2

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Eros Lazzerini Denchi

object named as

Eros Lazzerini Denchi

series ordinal

1

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language of work or name

English

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publication date

8 August 2007

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25 July 2017

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25 July 2017

448

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25 July 2017

7157

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25 July 2017

1068-1071

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https://scigraph.springernature.com/pub.10.1038/nature06065

25 July 2017

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cites work

Shelterin: the protein complex that shapes and safeguards human telomeres

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06065

7 January 2021

A DNA damage checkpoint response in telomere-initiated senescence

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06065

7 January 2021

p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06065

7 January 2021

DNA damage foci at dysfunctional telomeres

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06065

7 January 2021

Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06065

7 January 2021

Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06065

7 January 2021

DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06065

7 January 2021

Different telomere damage signaling pathways in human and mouse cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06065

7 January 2021

Atm-deficient mice: a paradigm of ataxia telangiectasia

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06065

7 January 2021

Hepatocytes with extensive telomere deprotection and fusion remain viable and regenerate liver mass through endoreduplication

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06065

7 January 2021

ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06065

7 January 2021

MDC1 accelerates nonhomologous end-joining of dysfunctional telomeres

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06065

7 January 2021

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06065

7 January 2021

The maintenance and masking of chromosome termini

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06065

7 January 2021

MEC3, MEC1, and DDC2 are essential components of a telomere checkpoint pathway required for cell cycle arrest during senescence in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06065

7 January 2021

Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06065

7 January 2021

Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06065

7 January 2021

Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06065

7 January 2021

Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06065

7 January 2021

Telomere protection by mammalian Pot1 requires interaction with Tpp1

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06065

7 January 2021

ATR and ATRIP: partners in checkpoint signaling

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06065

7 January 2021

POT1 protects telomeres from a transient DNA damage response and determines how human chromosomes end

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https://api.crossref.org/works/10.1038%2FNATURE06065

7 January 2021

The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06065

7 January 2021

POT1 as a terminal transducer of TRF1 telomere length control

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06065

7 January 2021

Ku70 stimulates fusion of dysfunctional telomeres yet protects chromosome ends from homologous recombination

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06065

7 January 2021

Mammalian telomeres end in a large duplex loop

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06065

7 January 2021

Harmonising the response to DSBs: a new string in the ATM bow.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06065

7 January 2021

POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06065

7 January 2021

Identifiers

DOI

10.1038/NATURE06065

1 reference

PubMed ID

17687332

Dimensions Publication ID

25 July 2017

0 references

1 reference

PubMed ID

17687332