Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing (Q59086518)

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17 December 2019

title

Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing (English)

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17 December 2019

1

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17 December 2019

8

Ronald A DePinho

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17 December 2019

3

Robert M Bachoo

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17 December 2019

author name string

Jayant Menon

4

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17 December 2019

Yansong Gu

6

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17 December 2019

Richard S Maser

2

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17 December 2019

Daniel R Carrasco

5

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17 December 2019

Frederick W Alt

7

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17 December 2019

language of work or name

English

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publication date

22 January 2003

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17 December 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12540856%20AND%20SRC:MED&resulttype=core&format=json

17 December 2019

volume

421

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17 December 2019

issue

6923

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17 December 2019

page(s)

643-648

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https://scigraph.springernature.com/pub.10.1038/nature01385

17 December 2019

exact match

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cites work

Essential role of mouse telomerase in highly proliferative organs

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01385

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01385

The many substrates and functions of ATM

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01385

ATM function and telomere stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01385

p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01385

Pleiotropic defects in ataxia-telangiectasia protein-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01385

Telomere length dynamics and chromosomal instability in cells derived from telomerase null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01385

ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01385

Clonal and population analyses demonstrate that an EGF-responsive mammalian embryonic CNS precursor is a stem cell.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01385

Selective loss of dopaminergic nigro-striatal neurons in brains of Atm-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01385

Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01385

p53 mutant mice that display early ageing-associated phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01385

Different telomere damage signaling pathways in human and mouse cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01385

Genetic interactions between ATM and the nonhomologous end-joining factors in genomic stability and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01385

Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01385

Abnormal development of Purkinje cells and lymphocytes in Atm mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01385

Extra-chromosomal telomeric DNA in cells from Atm-/- mice and patients with ataxia-telangiectasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01385

ATM: genome stability, neuronal development, and cancer cross paths

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01385

7 January 2021

Accelerated telomere shortening in ataxia telangiectasia

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01385

7 January 2021

Atm-deficient mice: a paradigm of ataxia telangiectasia

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01385

7 January 2021

Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01385

7 January 2021

Hypervariable ultra-long telomeres in mice

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01385

7 January 2021

p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01385

7 January 2021

Gut instincts: thoughts on intestinal epithelial stem cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01385

7 January 2021

BDNF enhances the differentiation but not the survival of CNS stem cell-derived neuronal precursors

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01385

7 January 2021

Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01385

7 January 2021

Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01385

7 January 2021

DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01385

7 January 2021

Identifiers

DOI

10.1038/NATURE01385

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12540856%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

17 December 2019

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1 reference