Importance of a C-terminal conserved region of Chk1 for checkpoint function (Q33313883)

25 July 2017

title

Importance of a C-terminal conserved region of Chk1 for checkpoint function (English)

1 reference

25 July 2017

Carmela Palermo

1

1 reference

25 July 2017

Justin C Hope

2

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25 July 2017

Greg A Freyer

3

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25 July 2017

Hui Rao

4

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25 July 2017

Nancy C Walworth

5

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25 July 2017

language of work or name

English

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publication date

9 January 2008

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25 July 2017

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25 July 2017

volume

3

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25 July 2017

issue

1

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25 July 2017

page(s)

e1427

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Creative Commons Attribution 4.0 International

25 July 2017

copyright license

start time

9 January 2008

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Selective Chk1 inhibitors differentially sensitize p53-deficient cancer cells to cancer therapeutics

14 July 2018

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Site-specific phosphorylation of a checkpoint mediator protein controls its responses to different DNA structures

14 July 2018

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Assaying the DNA damage checkpoint in fission yeast

14 July 2018

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A novel protein with similarities to Rb binding protein 2 compensates for loss of Chk1 function and affects histone modification in fission yeast

14 July 2018

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Regulation of Chk1 kinase by autoinhibition and ATR-mediated phosphorylation

14 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173936

Phosphorylation activates Chk1 and is required for checkpoint-mediated cell cycle arrest

14 July 2018

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Determination of substrate motifs for human Chk1 and hCds1/Chk2 by the oriented peptide library approach.

14 July 2018

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Cloning and characterization of liver-specific isoform of Chk1 gene from rat

14 July 2018

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Serine-345 is required for Rad3-dependent phosphorylation and function of checkpoint kinase Chk1 in fission yeast

14 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173936

Cell cycle checkpoint signaling through the ATM and ATR kinases

14 July 2018

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ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1

14 July 2018

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ATM and ATR: networking cellular responses to DNA damage

14 July 2018

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Cytoplasmic occurrence of the Chk1/Cdc25 pathway and regulation of Chk1 in Xenopus oocytes

14 July 2018

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Claspin, a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts

14 July 2018

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Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts

14 July 2018

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Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint

14 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173936

The 1.7 A crystal structure of human cell cycle checkpoint kinase Chk1: implications for Chk1 regulation

14 July 2018

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An indolocarbazole inhibitor of human checkpoint kinase (Chk1) abrogates cell cycle arrest caused by DNA damage

14 July 2018

1 reference

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Association of Chk1 with 14-3-3 proteins is stimulated by DNA damage

14 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173936

Analysis of Rad3 and Chk1 protein kinases defines different checkpoint responses.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173936

Replication checkpoint enforced by kinases Cds1 and Chk1.

14 July 2018

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S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173936

Damage and replication checkpoint control in fission yeast is ensured by interactions of Crb2, a protein with BRCT motif, with Cut5 and Chk1.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173936

Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173936

Isolation and characterization of the Schizosaccharomyces pombe rhp9 gene: a gene required for the DNA damage checkpoint but not the replication checkpoint

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173936

Chk1 is a wee1 kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173936

Fission yeast chk1 protein kinase links the rad checkpoint pathway to cdc2.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173936

Identification and characterization of new elements involved in checkpoint and feedback controls in fission yeast

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173936

Universal control mechanism regulating onset of M-phase

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173936

Molecular genetic analysis of fission yeast Schizosaccharomyces pombe

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173936

DNA repair mutants defining G2 checkpoint pathways in Schizosaccharomyces pombe

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173936

rad-dependent response of the chk1-encoded protein kinase at the DNA damage checkpoint.

14 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001427

14-3-3 protein homologs required for the DNA damage checkpoint in fission yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001427

Cdc25 Mitotic Inducer Targeted by Chk1 DNA Damage Checkpoint Kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001427

A novel genetic screen identifies checkpoint-defective alleles of Schizosaccharomyces pombe chk1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001427

Fission yeast chk1 mutants show distinct responses to different types of DNA damaging treatments

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001427

DNA damage checkpoint maintenance through sustained Chk1 activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001427

A kinase from fission yeast responsible for blocking mitosis in S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001427

Temperature-sensitive lethal mutants in the structural gene for dna ligase in the yeast schizosaccharomyces pombe

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001427

Chk1 is required for spindle checkpoint function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001427

Substrate specificity determinants of the checkpoint protein kinase Chk1

21 January 2018

1 reference

12 December 2020

Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I

1 reference

12 December 2020

Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin

1 reference

12 December 2020

Fission yeast genes involved in coupling mitosis to completion of DNA replication

1 reference

12 December 2020

Thiamine-repressible expression vectors pREP and pRIP for fission yeast

1 reference

12 December 2020

Two new multi-purpose multicopy Schizosaccharomyces pombe shuttle vectors, pSP1 and pSP2

1 reference

12 December 2020

The topoisomerase I poison camptothecin generates a Chk1-dependent DNA damage checkpoint signal in fission yeast

1 reference

12 December 2020

Functional transitions in myosin: role of highly conserved Gly and Glu residues in the active site

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0001427

Identifiers

DOI

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25 July 2017

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25 July 2017

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