Vav3 oncogene activates estrogen receptor and its overexpression may be involved in human breast cancer (Q33339736)

25 July 2017

Vav3 oncogene activates estrogen receptor and its overexpression may be involved in human breast cancer (English)

1 reference

25 July 2017

1 reference

1 reference

1 reference

Jinsong Zhang

4

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author name string

Kiwon Lee

1

1 reference

25 July 2017

Yin Liu

2

1 reference

25 July 2017

Jun Qin Mo

3

1 reference

25 July 2017

Zhongyun Dong

5

1 reference

25 July 2017

Shan Lu

6

1 reference

25 July 2017

language of work or name

English

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publication date

2 June 2008

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25 July 2017

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25 July 2017

8

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25 July 2017

158

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https://scigraph.springernature.com/pub.10.1186/1471-2407-8-158

25 July 2017

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Long-term treatment with tamoxifen facilitates translocation of estrogen receptor alpha out of the nucleus and enhances its interaction with EGFR in MCF-7 breast cancer cells

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Phosphorylation of MNAR promotes estrogen activation of phosphatidylinositol 3-kinase

21 June 2018

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Vav3, a Rho GTPase guanine nucleotide exchange factor, increases during progression to androgen independence in prostate cancer cells and potentiates androgen receptor transcriptional activity

21 June 2018

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AND-34 activates phosphatidylinositol 3-kinase and induces anti-estrogen resistance in a SH2 and GDP exchange factor-like domain-dependent manner.

21 June 2018

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E protein silencing by the leukemogenic AML1-ETO fusion protein

21 June 2018

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Endocrine-responsive breast cancer and strategies for combating resistance

21 June 2018

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Mechanism of epidermal growth factor regulation of Vav2, a guanine nucleotide exchange factor for Rac

21 June 2018

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Structural determinants for the biological activity of Vav proteins.

21 June 2018

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Vav1 is a component of transcriptionally active complexes.

21 June 2018

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The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK pathway through the integral subunit GPS2

21 June 2018

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Distinct role of phosphatidylinositol 3-kinase and Rho family GTPases in Vav3-induced cell transformation, cell motility, and morphological changes

21 June 2018

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The role of genetic abnormalities of PTEN and the phosphatidylinositol 3-kinase pathway in breast and ovarian tumorigenesis, prognosis, and therapy

21 June 2018

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Vav proteins, adaptors and cell signaling.

21 June 2018

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Estrogen receptor and breast cancer

21 June 2018

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Vav3 mediates receptor protein tyrosine kinase signaling, regulates GTPase activity, modulates cell morphology, and induces cell transformation

21 June 2018

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Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation

21 June 2018

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Vav family proteins couple to diverse cell surface receptors

21 June 2018

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21 June 2018

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Tyrosine phosphorylation mediates both activation and downmodulation of the biological activity of Vav

21 June 2018

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Regulatory and signaling properties of the Vav family

21 June 2018

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Molecular mechanisms of androgen-independent growth of human prostate cancer LNCaP-AI cells

21 June 2018

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Biological and regulatory properties of Vav-3, a new member of the Vav family of oncoproteins

21 June 2018

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From HER2/Neu signal cascade to androgen receptor and its coactivators: a novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells

21 June 2018

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The coactivator TIF2 contains three nuclear receptor-binding motifs and mediates transactivation through CBP binding-dependent and -independent pathways

21 June 2018

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vav, a novel human oncogene derived from a locus ubiquitously expressed in hematopoietic cells

21 June 2018

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Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease

21 June 2018

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Akt1 ablation inhibits, whereas Akt2 ablation accelerates, the development of mammary adenocarcinomas in mouse mammary tumor virus (MMTV)-ErbB2/neu and MMTV-polyoma middle T transgenic mice

21 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2F1471-2407-8-158

PIK3CA mutations in breast cancer are associated with poor outcome

21 January 2018

1 reference

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Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2430719

Mice expressing myrAKT1 in the mammary gland develop carcinogen-induced ER-positive mammary tumors that mimic human breast cancer

31 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2F1471-2407-8-158

Ligand-independent recruitment of SRC-1 to estrogen receptor beta through phosphorylation of activation function AF-1

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18518979

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Gene amplification and expression of the steroid receptor coactivator SRC3 (AIB1) in sporadic breast and endometrial carcinomas

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18518979

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1471-2407-8-158

1 reference

Dimensions Publication ID

25 July 2017

0 references

1 reference

25 July 2017

1 reference