Distinct functions of POT1 at telomeres (Q33339823)

25 July 2017

title

Distinct functions of POT1 at telomeres (English)

1 reference

25 July 2017

author name string

Katharine S Barrientos

1

1 reference

25 July 2017

Megan F Kendellen

2

1 reference

25 July 2017

Brian D Freibaum

3

1 reference

25 July 2017

Blaine N Armbruster

4

1 reference

25 July 2017

Katherine T Etheridge

5

1 reference

25 July 2017

Christopher M Counter

6

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25 July 2017

language of work or name

English

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publication date

2 June 2008

1 reference

Molecular and Cellular Biology

25 July 2017

published in

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25 July 2017

volume

28

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25 July 2017

issue

17

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25 July 2017

page(s)

5251-5264

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Telomere dysfunction and cell survival: roles for distinct TIN2-containing complexes

25 July 2017

cites work

1 reference

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Functional diversity of human protection of telomeres 1 isoforms in telomere protection and cellular senescence

14 July 2018

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Dysfunctional telomeres activate an ATM-ATR-dependent DNA damage response to suppress tumorigenesis

14 July 2018

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Protection of telomeres by a conserved Stn1-Ten1 complex

14 July 2018

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Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1.

14 July 2018

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Telomere protection by mammalian Pot1 requires interaction with Tpp1

14 July 2018

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Telomere maintenance through spatial control of telomeric proteins

14 July 2018

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RPA-like proteins mediate yeast telomere function

14 July 2018

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The POT1-TPP1 telomere complex is a telomerase processivity factor

14 July 2018

1 reference

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TPP1 is a homologue of ciliate TEBP-beta and interacts with POT1 to recruit telomerase

14 July 2018

1 reference

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POT1b protects telomeres from end-to-end chromosomal fusions and aberrant homologous recombination

14 July 2018

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Vertebrate POT1 restricts G-overhang length and prevents activation of a telomeric DNA damage checkpoint but is dispensable for overhang protection

14 July 2018

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A critical role for TPP1 and TIN2 interaction in high-order telomeric complex assembly

14 July 2018

1 reference

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Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres

14 July 2018

1 reference

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Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres

14 July 2018

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A comprehensive structure-function analysis of Arabidopsis SNI1 defines essential regions and transcriptional repressor activity

14 July 2018

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A genetically defined normal human somatic cell system to study ras oncogenesis in vivo and in vitro

14 July 2018

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POT1 protects telomeres from a transient DNA damage response and determines how human chromosomes end

14 July 2018

1 reference

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Human telomeres maintain their overhang length at senescence

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

POT1 and TRF2 cooperate to maintain telomeric integrity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

Extended DNA binding site in Pot1 broadens sequence specificity to allow recognition of heterogeneous fission yeast telomeres

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

Loss of hPot1 function leads to telomere instability and a cut-like phenotype

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

Human Rif1 protein binds aberrant telomeres and aligns along anaphase midzone microtubules

14 July 2018

1 reference

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Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection

14 July 2018

1 reference

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Telosome, a mammalian telomere-associated complex formed by multiple telomeric proteins

14 July 2018

1 reference

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A dynamic molecular link between the telomere length regulator TRF1 and the chromosome end protector TRF2

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

TIN2 binds TRF1 and TRF2 simultaneously and stabilizes the TRF2 complex on telomeres

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

TIN2 mediates functions of TRF2 at human telomeres

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

PTOP interacts with POT1 and regulates its localization to telomeres

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

Rescue of an hTERT mutant defective in telomere elongation by fusion with hPot1

14 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

DNA binding features of human POT1: a nonamer 5'-TAGGGTTAG-3' minimal binding site, sequence specificity, and internal binding to multimeric sites

14 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

DNA damage foci at dysfunctional telomeres

14 July 2018

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Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

POT1 as a terminal transducer of TRF1 telomere length control

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

Putative Telomere-Recruiting Domain in the Catalytic Subunit of Human Telomerase

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

Human Pot1 (protection of telomeres) protein: cytolocalization, gene structure, and alternative splicing

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

Distinct requirements for Ras oncogenesis in human versus mouse cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

N-terminal domains of the human telomerase catalytic subunit required for enzyme activity in vivo

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

Pot1, the putative telomere end-binding protein in fission yeast and humans

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

Synergistic coupling of histone H3 phosphorylation and acetylation in response to epidermal growth factor stimulation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

Control of human telomere length by TRF1 and TRF2

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

TIN2, a new regulator of telomere length in human cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

Mammalian telomeres end in a large duplex loop

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

Crystal structure of the Oxytricha nova telomere end binding protein complexed with single strand DNA

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

TRF2 Protects Human Telomeres from End-to-End Fusions

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

Control of telomere length by the human telomeric protein TRF1

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

Cdc13p: a single-strand telomeric DNA-binding protein with a dual role in yeast telomere maintenance

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

Oxytricha telomere-binding protein: DNA-dependent dimerization of the alpha and beta subunits

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

Identical short peptide sequences in unrelated proteins can have different conformations: a testing ground for theories of immune recognition.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

A series of mammalian expression vectors and characterisation of their expression of a reporter gene in stably and transiently transfected cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

Cloning and expression of genes for the Oxytricha telomere-binding protein: specific subunit interactions in the telomeric complex

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

Homology among telomeric end-protection proteins

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519730

31 October 2018

Identifiers

DOI

10.1128/MCB.00048-08

1 reference

25 July 2017

1 reference

25 July 2017

1 reference