Critical involvement of the ATM-dependent DNA damage response in the apoptotic demise of HIV-1-elicited syncytia (Q33344436)

26 July 2017

Critical involvement of the ATM-dependent DNA damage response in the apoptotic demise of HIV-1-elicited syncytia (English)

1 reference

26 July 2017

0 references

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21

Guido Kroemer

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Hugues de Thé

18

Hugues de Thé

0 references

Alessandra Amendola

Alessandra Amendola

9

0 references

Jean-Luc Perfettini

Jean-Luc Perfettini

1

0 references

José R Regueiro

José R Regueiro

17

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Giuseppe Novelli

Giuseppe Novelli

12

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Magdalena Chechlinska

Magdalena Chechlinska

15

0 references

Jan Siwicki

14

Jan Konrad Siwicki

1 reference

26 July 2017

20

Mauro Piacentini

1 reference

26 July 2017

Roberta Nardacci

2

1 reference

26 July 2017

Mehdi Bourouba

3

1 reference

26 July 2017

Frédéric Subra

4

1 reference

26 July 2017

Laurent Gros

5

1 reference

26 July 2017

Claire Séror

6

1 reference

26 July 2017

Gwenola Manic

7

1 reference

26 July 2017

Filippo Rosselli

8

1 reference

26 July 2017

Peggy Masdehors

10

1 reference

26 July 2017

Luciana Chessa

11

1 reference

26 July 2017

David M Ojcius

13

1 reference

26 July 2017

Christian Auclair

16

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26 July 2017

Marie-Lise Gougeon

19

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26 July 2017

language of work or name

English

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publication date

18 June 2008

1 reference

26 July 2017

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26 July 2017

3

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26 July 2017

e2458

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26 July 2017

6

1 reference

Creative Commons Attribution 4.0 International

26 July 2017

start time

18 June 2008

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

gammaH2AX foci form preferentially in euchromatin after ionising-radiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

Rapid activation of ATM on DNA flanking double-strand breaks

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

Image-based modeling reveals dynamic redistribution of DNA damage into nuclear sub-domains

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

Distinct domains in Nbs1 regulate irradiation-induced checkpoints and apoptosis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

Characterization of cell death pathways in human immunodeficiency virus-associated encephalitis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models

14 July 2018

1 reference

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p53-A pro-apoptotic signal transducer involved in AIDS

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

Inhibition of HIV-1 replication by caffeine and caffeine-related methylxanthines

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

Retroviral DNA integration and the DNA damage response

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

Mechanisms of apoptosis induction by the HIV-1 envelope

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

Essential role of p53 phosphorylation by p38 MAPK in apoptosis induction by the HIV-1 envelope

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

The neuropathogenesis of AIDS

14 July 2018

1 reference

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Human immunodeficiency virus type 1 Vpr-mediated G2 arrest requires Rad17 and Hus1 and induces nuclear BRCA1 and gamma-H2AX focus formation.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

Progressive multifocal leukencephalopathy in patients on highly active antiretroviral therapy: survival and risk factors of death

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

PML nuclear bodies: dynamic sensors of DNA damage and cellular stress

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

The changing face of the HIV epidemic in western Europe: what are the implications for public health policies?

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

NF-kappaB and p53 are the dominant apoptosis-inducing transcription factors elicited by the HIV-1 envelope

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

Induction of ATF3 by ionizing radiation is mediated via a signaling pathway that includes ATM, Nibrin1, stress-induced MAPkinases and ATF-2.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

Telomere maintenance and cell cycle regulation in spontaneously immortalized T-cell lines from Nijmegen breakage syndrome patients.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

Apoptosis as an HIV strategy to escape immune attack

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

Vpr R77Q is associated with long-term nonprogressive HIV infection and impaired induction of apoptosis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

Activation of the ATR-mediated DNA damage response by the HIV-1 viral protein R.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

The ATR-independent DNA replication checkpoint

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

Evidence that the retroviral DNA integration process triggers an ATR-dependent DNA damage response

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

Relevance of viral phenotype in the early AIDS outcome of pediatric HIV-1 primary infection

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

ATM mediates phosphorylation at multiple p53 sites, including Ser(46), in response to ionizing radiation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

Human immunodeficiency virus 1 envelope glycoprotein complex-induced apoptosis involves mammalian target of rapamycin/FKBP12-rapamycin-associated protein-mediated p53 phosphorylation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

ATM phosphorylates histone H2AX in response to DNA double-strand breaks

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

Mechanisms of HIV-associated lymphocyte apoptosis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

Involvement of the MKK6-p38gamma cascade in gamma-radiation-induced cell cycle arrest

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

Envelope glycoprotein determinants of increased fusogenicity in a pathogenic simian-human immunodeficiency virus (SHIV-KB9) passaged in vivo

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

Human immunodeficiency virus type 1 pathogenesis in SCID-hu mice correlates with syncytium-inducing phenotype and viral replication

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

In vivo HIV-1 infection of CD45RA(+)CD4(+) T cells is established primarily by syncytium-inducing variants and correlates with the rate of CD4(+) T cell decline

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

ATM associates with and phosphorylates p53: mapping the region of interaction

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

Enhanced phosphorylation of p53 by ATM in response to DNA damage

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

Vpr stimulates viral expression and induces cell killing in human immunodeficiency virus type 1-infected dividing Jurkat T cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

Cellular localization of human immunodeficiency virus infection within the brains of acquired immune deficiency syndrome patients

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

Highly active antiretroviral therapy and human immunodeficiency virus encephalitis

14 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002458

Apoptosis of syncytia induced by the HIV-1-envelope glycoprotein complex: influence of cell shape and size.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002458

The glial response to CNS HIV infection includes p53 activation and increased expression of p53 target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002458

DNA damage-mediated apoptosis induced by selenium compounds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002458

Suppression of HIV-1 infection by a small molecule inhibitor of the ATM kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002458

Two-step activation of ATM by DNA and the Mre11-Rad50-Nbs1 complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002458

Membrane and transmembrane signaling in Herpesvirus saimiri-transformed human CD4(+) and CD8(+) T lymphocytes is ATM-independent.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002458

HIV associated neurodegeneration requires p53 in neurons and microglia.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423469

Syncytium formation amplifies apoptotic signals: a new view on apoptosis in HIV infection in vitro

31 October 2018

1 reference

12 December 2020

Apoptosis in HIV infection

1 reference

12 December 2020

Genotoxicity and mitochondrial damage in human lymphocytic cells chronically exposed to 3'-azido-2',3'-dideoxythymidine

1 reference

12 December 2020

To kill or be killed: how HIV exhausts the immune system

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0002458

Identifiers

DOI

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26 July 2017

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26 July 2017

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