HIV-induced type I interferon and tryptophan catabolism drive T cell dysfunction despite phenotypic activation (Q33359564)

26 July 2017

HIV-induced type I interferon and tryptophan catabolism drive T cell dysfunction despite phenotypic activation (English)

1 reference

26 July 2017

Adriano Boasso

1

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author name string

Andrew W Hardy

2

1 reference

26 July 2017

Stephanie A Anderson

3

1 reference

26 July 2017

Matthew J Dolan

4

1 reference

26 July 2017

Gene M Shearer

5

1 reference

26 July 2017

language of work or name

English

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publication date

13 August 2008

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26 July 2017

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26 July 2017

3

1 reference

26 July 2017

e2961

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26 July 2017

8

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Creative Commons CC0 License

26 July 2017

start time

13 August 2008

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April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

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cites work

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HIV-1-driven regulatory T-cell accumulation in lymphoid tissues is associated with disease progression in HIV/AIDS.

21 June 2018

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Differential expression of IFN-alpha and TRAIL/DR5 in lymphoid tissue of progressor versus nonprogressor HIV-1-infected patients.

21 June 2018

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Studies of HIV-associated immune responses in lymphoid compartments

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Perturbations of cell cycle control in T cells contribute to the different outcomes of simian immunodeficiency virus infection in rhesus macaques and sooty mangabeys

21 June 2018

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HIV-infected cells are major inducers of plasmacytoid dendritic cell interferon production, maturation, and migration

21 June 2018

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Endocytosis of HIV-1 activates plasmacytoid dendritic cells via Toll-like receptor-viral RNA interactions

21 June 2018

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Regulation of TNF-related apoptosis-inducing ligand on primary CD4+ T cells by HIV-1: role of type I IFN-producing plasmacytoid dendritic cells

21 June 2018

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Indoleamine 2,3 dioxygenase and regulation of T cell immunity

21 June 2018

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21 June 2018

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CD4+ T-cell depletion in HIV infection: killed by friendly fire?

21 June 2018

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CD4+ T-cell death induced by infectious and noninfectious HIV-1: role of type 1 interferon-dependent, TRAIL/DR5-mediated apoptosis

21 June 2018

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Plasmacytoid dendritic cell precursors/type I interferon-producing cells sense viral infection by Toll-like receptor (TLR) 7 and TLR9.

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Tryptophan catabolism and T cell responses.

21 June 2018

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Cell-cycle dysregulation in the immunopathogenesis of AIDS.

21 June 2018

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B lymphocyte dysfunctions in HIV infection

21 June 2018

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Immune activation and CD8+ T-cell differentiation towards senescence in HIV-1 infection

21 June 2018

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Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration

21 June 2018

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The relationship between simian immunodeficiency virus RNA levels and the mRNA levels of alpha/beta interferons (IFN-alpha/beta) and IFN-alpha/beta-inducible Mx in lymphoid tissues of rhesus macaques during acute and chronic infection

21 June 2018

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Exogenous interleukin-2 administration corrects the cell cycle perturbation of lymphocytes from human immunodeficiency virus-infected individuals

21 June 2018

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Deregulation of the expression of the fractalkine/fractalkine receptor complex in HIV-1-infected patients

21 June 2018

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Dressed to kill? A review of why antiviral CD8 T lymphocytes fail to prevent progressive immunodeficiency in HIV-1 infection

21 June 2018

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Induction of indoleamine 2,3-dioxygenase in primary human macrophages by HIV-1.

21 June 2018

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Human immunodeficiency virus-specific circulating CD8 T lymphocytes have down-modulated CD3zeta and CD28, key signaling molecules for T-cell activation

21 June 2018

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CD38+CD8+ T cells as a marker of poor response to therapy in HIV-infected individuals

21 June 2018

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Induction of indolamine 2,3-dioxygenase in primary human macrophages by human immunodeficiency virus type 1 is strain dependent

21 June 2018

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Activation of CD8 T cells normalizes and correlates with the level of infectious provirus in tonsils during highly active antiretroviral therapy in early HIV-1 infection

21 June 2018

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Cluster of differentiation antigen 4 (CD4) endocytosis and adaptor complex binding require activation of the CD4 endocytosis signal by serine phosphorylation

21 June 2018

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Shorter survival in advanced human immunodeficiency virus type 1 infection is more closely associated with T lymphocyte activation than with plasma virus burden or virus chemokine coreceptor usage.

21 June 2018

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Lack of p56lck expression correlates with CD4 endocytosis in primary lymphoid and myeloid cells

21 June 2018

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Inactivation of human immunodeficiency virus type 1 infectivity with preservation of conformational and functional integrity of virion surface proteins.

21 June 2018

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Quantitation of human immunodeficiency virus type 1 infection kinetics

21 June 2018

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High levels of HIV-1 in plasma during all stages of infection determined by competitive PCR

21 June 2018

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Chronic activation of the immune system in HIV infection: contribution to T cell apoptosis and V beta selective T cell anergy.

21 June 2018

1 reference

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Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2491901

The role of the cell cycle in HIV-1 infection

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2491901

T cell apoptosis as a consequence of chronic activation of the immune system in HIV infection.

21 June 2018

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Acquired immunodeficiency syndrome (AIDS).

21 June 2018

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Detection of three distinct patterns of T helper cell dysfunction in asymptomatic, human immunodeficiency virus-seropositive patients. Independence of CD4+ cell numbers and clinical staging

21 June 2018

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Immunology of the human immunodeficiency virus infection

21 June 2018

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In vitro T cell function, delayed-type hypersensitivity skin testing, and CD4+ T cell subset phenotyping independently predict survival time in patients infected with human immunodeficiency virus

21 June 2018

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CD4 T cell depletion is linked directly to immune activation in the pathogenesis of HIV-1 and HIV-2 but only indirectly to the viral load.

21 January 2018

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CD8+ T cells specific for EBV, cytomegalovirus, and influenza virus are activated during primary HIV infection.

21 January 2018

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The prevalence of regulatory T cells in lymphoid tissue is correlated with viral load in HIV-infected patients.

21 January 2018

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GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase.

21 January 2018

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Impact of class A, B and C CpG-oligodeoxynucleotides on in vitro activation of innate immune cells in human immunodeficiency virus-1 infected individuals.

21 January 2018

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In vitro treatment of human monocytes/macrophages with myristoylated recombinant Nef of human immunodeficiency virus type 1 leads to the activation of mitogen-activated protein kinases, IkappaB kinases, and interferon regulatory factor 3 and to the r

21 January 2018

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Quinolinic acid is produced by macrophages stimulated by platelet activating factor, Nef and Tat.

21 January 2018

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Mucosal but not peripheral FOXP3+ regulatory T cells are highly increased in untreated HIV infection and normalize after suppressive HAART.

21 January 2018

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Premature induction of an immunosuppressive regulatory T cell response during acute simian immunodeficiency virus infection

21 January 2018

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21 January 2018

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The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor zeta-chain and induce a regulatory phenotype in naive T cells

21 January 2018

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31 October 2018

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Lack of chronic immune activation in HIV-infected chimpanzees correlates with the resistance of T cells to Fas/Apo-1 (CD95)-induced apoptosis and preservation of a T helper 1 phenotype

31 October 2018

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Elevated levels of CD38+ CD8+ T cells in HIV infection add to the prognostic value of low CD4+ T cell levels: results of 6 years of follow-up. The Los Angeles Center, Multicenter AIDS Cohort Study

31 October 2018

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Immunologic and virologic evaluation after influenza vaccination of HIV-1-infected patients

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Natural history of HIV-1 infection

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12 December 2020

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Indirect mechanisms of HIV pathogenesis: how does HIV kill T cells?

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Elevated CD38 antigen expression on CD8+ T cells is a stronger marker for the risk of chronic HIV disease progression to AIDS and death in the Multicenter AIDS Cohort Study than CD4+ cell count, soluble immune activation markers, or combinations of

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Plasmacytoid dendritic cell precursors induce allogeneic T-cell hyporesponsiveness and prolong heart graft survival

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B7-H1 up-regulation on myeloid dendritic cells significantly suppresses T cell immune function in patients with chronic hepatitis B

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Parallel loss of myeloid and plasmacytoid dendritic cells from blood and lymphoid tissue in simian AIDS

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12 December 2020

10.1371/JOURNAL.PONE.0002961

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26 July 2017

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1 reference

26 July 2017

1 reference