Plant sterols cause macrothrombocytopenia in a mouse model of sitosterolemia. (Q33378034)

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31 December 2019

title

Plant sterols cause macrothrombocytopenia in a mouse model of sitosterolemia (English)

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31 December 2019

main subject

Giant platelet disorder

1 reference

1

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31 December 2019

Vincent Walter Bloks

3

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31 December 2019

author name string

A Lyndsay Drayer

2

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31 December 2019

Nel Blom

4

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31 December 2019

Sandra G Olthof

5

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31 December 2019

Pieter J J Sauer

6

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31 December 2019

Gerald de Haan

7

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31 December 2019

Ido P Kema

8

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31 December 2019

Edo Vellenga

9

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31 December 2019

Folkert Kuipers

10

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31 December 2019

language of work or name

English

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publication date

21 December 2007

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Journal of Biological Chemistry

31 December 2019

published in

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31 December 2019

volume

283

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31 December 2019

issue

10

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31 December 2019

page(s)

6281-6287

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Identification of plant sterols in plasma and red blood cells of man and experimental animals

31 December 2019

cites work

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Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion

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Expression and regulation of the sterol half-transporter genes ABCG5 and ABCG8 in rats

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Specific gene expression of ATP-binding cassette transporters and nuclear hormone receptors in rat liver parenchymal, endothelial, and Kupffer cells

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Two genes that map to the STSL locus cause sitosterolemia: genomic structure and spectrum of mutations involving sterolin-1 and sterolin-2, encoded by ABCG5 and ABCG8, respectively

21 January 2018

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Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters

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Beta-sitosterolemia and xanthomatosis. A newly described lipid storage disease in two sisters

21 January 2018

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Phytosterolaemia, xanthomatosis and premature atherosclerotic arterial disease: a case with high plant sterol absorption, impaired sterol elimination and low cholesterol synthesis

21 January 2018

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β-Sitosterolemia and Xanthomatosis

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Phytosterolaemia in three unrelated South African families

21 January 2018

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Stomatocytic haemolysis and macrothrombocytopenia (Mediterranean stomatocytosis/macrothrombocytopenia) is the haematological presentation of phytosterolaemia

21 January 2018

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Sitosterolemia in ABC-transporter G5-deficient mice is aggravated on activation of the liver-X receptor.

21 January 2018

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Mathematical modeling of the osmotic fragility of rabbit red blood cells.

21 January 2018

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Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles

21 January 2018

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Increased fecal neutral sterol loss upon liver X receptor activation is independent of biliary sterol secretion in mice.

21 January 2018

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Increased hepatobiliary and fecal cholesterol excretion upon activation of the liver X receptor is independent of ABCA1.

21 January 2018

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Ultrastructural study shows morphologic features of apoptosis and para-apoptosis in megakaryocytes from patients with idiopathic thrombocytopenic purpura

21 January 2018

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The molecular and cellular biology of thrombopoietin: the primary regulator of platelet production

21 January 2018

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Ezetimibe effectively reduces plasma plant sterols in patients with sitosterolemia

21 January 2018

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Intestinal cholesterol absorption inhibitor ezetimibe added to cholestyramine for sitosterolemia and xanthomatosis.

21 January 2018

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Ezetimibe normalizes metabolic defects in mice lacking ABCG5 and ABCG8.

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Reduction of Serum Cholesterol with Sitostanol-Ester Margarine in a Mildly Hypercholesterolemic Population

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Comparison of the intestinal uptake of cholesterol, plant sterols, and stanols in mice

21 January 2018

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Niemann-Pick C1 Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis

21 January 2018

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Compared with Acyl-CoA:cholesterol O-acyltransferase (ACAT) 1 and lecithin:cholesterol acyltransferase, ACAT2 displays the greatest capacity to differentiate cholesterol from sitosterol

21 January 2018

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Common sequence variations in ABCG8 are related to plant sterol metabolism in healthy volunteers

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Identifiers

DOI

10.1074/JBC.M706689200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18156627%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference