CTLA-4 activation of phosphatidylinositol 3-kinase (PI 3-K) and protein kinase B (PKB/AKT) sustains T-cell anergy without cell death (Q33389175)

26 July 2017

CTLA-4 activation of phosphatidylinositol 3-kinase (PI 3-K) and protein kinase B (PKB/AKT) sustains T-cell anergy without cell death (English)

1 reference

26 July 2017

1 reference

4

Christopher E Rudd

1 reference

26 July 2017

Helga Schneider

1

1 reference

26 July 2017

Elke Valk

series ordinal

2

1 reference

26 July 2017

Rufina Leung

series ordinal

3

1 reference

26 July 2017

language of work or name

English

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publication date

4 December 2008

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26 July 2017

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26 July 2017

3

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26 July 2017

12

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26 July 2017

e3842

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Creative Commons Attribution 4.0 International

26 July 2017

start time

4 December 2008

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

PP2A regulates BCL-2 phosphorylation and proteasome-mediated degradation at the endoplasmic reticulum

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Pim kinases phosphorylate multiple sites on Bad and promote 14-3-3 binding and dissociation from Bcl-XL

21 June 2018

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CD152 (CTLA-4) determines the unequal resistance of Th1 and Th2 cells against activation-induced cell death by a mechanism requiring PI3 kinase function.

21 June 2018

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Unifying concepts in CD28, ICOS and CTLA4 co-receptor signalling

21 June 2018

1 reference

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The control of T cell activation vs. tolerance

21 June 2018

1 reference

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Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy.

21 June 2018

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Cutting edge: CTLA-4 (CD152) differentially regulates mitogen-activated protein kinases (extracellular signal-regulated kinase and c-Jun N-terminal kinase) in CD4+ T cells from receptor/ligand-deficient mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585791

Molecular mechanism for the regulation of protein kinase B/Akt by hydrophobic motif phosphorylation

21 June 2018

1 reference

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Protein kinase C and AKT/protein kinase B in CD4+ T-lymphocytes: new partners in TCR/CD28 signal integration

21 June 2018

1 reference

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GSK3 takes centre stage more than 20 years after its discovery

21 June 2018

1 reference

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CTLA-4 blockade of antigen-induced cell death

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585791

CTLA-4 up-regulation plays a role in tolerance mediated by CD45.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585791

The CD28 and CTLA-4 receptors associate with the serine/threonine phosphatase PP2A.

21 June 2018

1 reference

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Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation

21 June 2018

1 reference

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Cellular survival: a play in three Akts

21 June 2018

1 reference

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Apoptosis signaling in lymphocytes.

21 June 2018

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Molecular basis of T cell inactivation by CTLA-4

21 June 2018

1 reference

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Mechanism of activation and function of protein kinase B.

21 June 2018

1 reference

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The emerging role of CTLA-4 as an immune attenuator

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585791

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585791

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585791

Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585791

CTLA-4 binding to the lipid kinase phosphatidylinositol 3-kinase in T cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585791

CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585791

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585791

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585791

Distinct roles for CD28 and cytotoxic T lymphocyte-associated molecule-4 receptors during T cell activation?

21 June 2018

1 reference

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Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

21 June 2018

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Differential regulation of activation-induced cell death in individual human T cell clones.

21 June 2018

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Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003842

T cell tolerance and autoimmunity

21 January 2018

1 reference

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Polarization of naive CD4+ T cells toward the Th1 subset by CTLA-4 costimulation

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585791

Cytolytic T lymphocyte-associated antigen-4 and the TCR zeta/CD3 complex, but not CD28, interact with clathrin adaptor complexes AP-1 and AP-2

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585791

Blocking T-cell costimulation to prevent transplant rejection

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585791

Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585791

Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptors

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585791

The selective and inducible activation of endogenous PI 3-kinase in PC12 cells results in efficient NGF-mediated survival but defective neurite outgrowth

31 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003842

10.1371/JOURNAL.PONE.0003842

21 January 2018

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DOI

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26 July 2017

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26 July 2017

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