Optimization and validation of two miniaturized glucocerebrosidase enzyme assays for high throughput screening (Q33392239)

26 July 2017

title

Optimization and validation of two miniaturized glucocerebrosidase enzyme assays for high throughput screening (English)

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26 July 2017

2

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26 July 2017

Ajit Jadhav

4

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Christopher P Austin

8

object named as

Christopher P Austin

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26 July 2017

3

Ozlem Goker-Alpan

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26 July 2017

Daniel J Urban

1

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26 July 2017

Mary E Lamarca

5

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26 July 2017

James Inglese

6

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26 July 2017

Ellen Sidransky

7

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26 July 2017

language of work or name

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1 December 2008

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Combinatorial Chemistry & High Throughput Screening

26 July 2017

published in

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26 July 2017

volume

11

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26 July 2017

issue

10

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26 July 2017

page(s)

817-824

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Gaucher disease: mutation and polymorphism spectrum in the glucocerebrosidase gene (GBA).

26 July 2017

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Three classes of glucocerebrosidase inhibitors identified by quantitative high-throughput screening are chaperone leads for Gaucher disease

21 June 2018

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High-throughput screening assays for the identification of chemical probes

21 June 2018

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21 June 2018

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21 June 2018

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Structure of acid beta-glucosidase with pharmacological chaperone provides insight into Gaucher disease

21 June 2018

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Therapy for Gaucher disease: don't stop thinking about tomorrow

21 June 2018

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Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries

21 June 2018

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Therapeutic strategies to ameliorate lysosomal storage disorders--a focus on Gaucher disease

21 June 2018

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State-dependent compound inhibition of Nav1.2 sodium channels using the FLIPR Vm dye: on-target and off-target effects of diverse pharmacological agents

21 June 2018

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Miglustat (NB-DNJ) works as a chaperone for mutated acid beta-glucosidase in cells transfected with several Gaucher disease mutations

21 June 2018

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Gaucher disease: complexity in a "simple" disorder

21 June 2018

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A contradictory treatment for lysosomal storage disorders: inhibitors enhance mutant enzyme activity

21 June 2018

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Chemical chaperones increase the cellular activity of N370S beta -glucosidase: a therapeutic strategy for Gaucher disease

21 June 2018

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A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

21 June 2018

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Gaucher's disease: past, present and future

21 June 2018

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A flow cytometric assay for lysosomal glucocerebrosidase

21 June 2018

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Interaction of activating protein and surfactants with human liver hexosaminidase A and GM2 ganglioside

21 June 2018

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An improved method excluding hemoglobin interferences for lysosomal hydrolase assays using colorimetric synthetic substrates, 2-(N-hexadecanoylamino)-4-nitrophenol derivatives

21 June 2018

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6,7-Dichloroquinoxaline-2,3-dione is a competitive antagonist specific to strychnine-insensitive [3H]glycine binding sites on the N-methyl-D-aspartate receptor complex

21 June 2018

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Alpha-glucosidase activity in human leucocytes: Choice of lymphocytes for the diagnosis of Pompe's disease and the carrier state

21 June 2018

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Substrate specificities of the two genetically distinct human brain β-galactosidases

21 June 2018

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Human leukocyte acid hydrolases: Characterization of eleven lysosomal enzymes and study of reaction conditions for their automated analysis

21 June 2018

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X-ray structure of human acid-beta-glucosidase covalently bound to conduritol-B-epoxide. Implications for Gaucher disease

21 June 2018

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An in situ study of beta-glucosidase activity in normal and Gaucher fibroblasts with fluorogenic probes

31 October 2018

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Ebselen is a specific inhibitor of LTB4-mediated migration of human neutrophils.

31 October 2018

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Intracellular transport of acid beta-glucosidase and lysosome-associated membrane proteins is affected in Gaucher's disease (G202R mutation)

31 October 2018

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12 December 2020

A microassay for Gaucher's disease

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12 December 2020

Differentiation of beta-glucocerebrosidase from beta-glucosidase in human tissues using sodium taurocholate

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12 December 2020

beta-Glucosidase assays in the diagnosis of Gaucher's disease

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12 December 2020

Effects of ebselen and probucol on oxidative modifications of lipid and protein of low density lipoprotein induced by free radicals

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12 December 2020

Reversible inhibitors of beta-glucosidase

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12 December 2020

ER retention and degradation as the molecular basis underlying Gaucher disease heterogeneity

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12 December 2020

Expression of cytosolic beta-glucosidase in guinea pig liver cells

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12 December 2020

10.2174/138620708786734244

Identifiers

DOI

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26 July 2017

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26 July 2017

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