Absence of alpha-synuclein affects dopamine metabolism and synaptic markers in the striatum of aging mice (Q33394700)

26 July 2017

title

Absence of alpha-synuclein affects dopamine metabolism and synaptic markers in the striatum of aging mice (English)

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26 July 2017

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Paul A Jones

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Vladimir Buchman

object named as

Vladimir L Buchman

6

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Steven J Millership

object named as

Steven Millership

3

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author name string

Abdelmojib Al-Wandi

1

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26 July 2017

Natalia Ninkina

2

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26 July 2017

Sally J M Williamson

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26 July 2017

publication date

20 December 2008

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26 July 2017

published in

Neurobiology of Aging

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26 July 2017

volume

31

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26 July 2017

issue

5

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26 July 2017

page(s)

796-804

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Whole genome expression analyses of single- and double-knock-out mice implicate partially overlapping functions of alpha- and gamma-synuclein.

26 July 2017

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Developmental loss and resistance to MPTP toxicity of dopaminergic neurones in substantia nigra pars compacta of gamma-synuclein, alpha-synuclein and double alpha/gamma-synuclein null mutant mice

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Beta-synuclein displays an antiapoptotic p53-dependent phenotype and protects neurons from 6-hydroxydopamine-induced caspase 3 activation: cross-talk with alpha-synuclein and implication for Parkinson's disease

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Age-associated increases of alpha-synuclein in monkeys and humans are associated with nigrostriatal dopamine depletion: Is this the target for Parkinson's disease?

31 October 2018

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31 October 2018

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31 October 2018

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31 October 2018

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Mice lacking alpha-synuclein have an attenuated loss of striatal dopamine following prolonged chronic MPTP administration

31 October 2018

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Clearance of alpha-synuclein oligomeric intermediates via the lysosomal degradation pathway.

31 October 2018

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Role of alpha-synuclein in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice

31 October 2018

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α-Synuclein Is Degraded by Both Autophagy and the Proteasome

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146702

Golgi fragmentation occurs in the cells with prefibrillar alpha-synuclein aggregates and precedes the formation of fibrillar inclusion

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146702

Vesicle permeabilization by protofibrillar alpha-synuclein is sensitive to Parkinson's disease-linked mutations and occurs by a pore-like mechanism.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146702

Vesicle permeabilization by protofibrillar alpha-synuclein: implications for the pathogenesis and treatment of Parkinson's disease

31 October 2018

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Pathologic and biochemical studies of juvenile parkinsonism linked to chromosome 6q.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146702

Localization of phosphoneuroprotein 14 (PNP 14) and its mRNA expression in rat brain determined by immunocytochemistry and in situ hybridization

31 October 2018

1 reference

12 December 2020

Increased caudate dopamine turnover may contribute to the recovery of motor function in marmosets treated with the dopaminergic neurotoxin MPTP

1 reference

12 December 2020

Time course of adaptations in dopamine biosynthesis, metabolism, and release following nigrostriatal lesions: implications for behavioral recovery from brain injury

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12 December 2020

Peripheral sensory neurons survive in the absence of alpha- and gamma-synucleins

1 reference

12 December 2020

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12 December 2020

Estimation of nuclear population from microtome sections

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12 December 2020

Beta-synuclein inhibits formation of alpha-synuclein protofibrils: a possible therapeutic strategy against Parkinson's disease

1 reference

12 December 2020

10.1016/J.NEUROBIOLAGING.2008.11.001

Identifiers

DOI

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26 July 2017

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26 July 2017

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