A phase I study of two dosing schedules of volasertib (BI 6727), an intravenous polo-like kinase inhibitor, in patients with advanced solid malignancies. (Q33414793)

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English	A phase I study of two dosing schedules of volasertib (BI 6727), an intravenous polo-like kinase inhibitor, in patients with advanced solid malignancies.	scientific article

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15 March 2020

A phase I study of two dosing schedules of volasertib (BI 6727), an intravenous polo-like kinase inhibitor, in patients with advanced solid malignancies (English)

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15 March 2020

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15 March 2020

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15 March 2020

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15 March 2020

James Chih-Hsin Yang

13

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15 March 2020

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C-C Lin

1

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15 March 2020

W-C Su

2

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15 March 2020

C-J Yen

3

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15 March 2020

W-P Su

5

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15 March 2020

Y-S Lu

7

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15 March 2020

D C-L Huang

9

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15 March 2020

H Fritsch

10

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15 March 2020

F Voss

11

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15 March 2020

T Taube

12

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15 March 2020

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22 April 2014

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15 March 2020

British Journal of Cancer

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15 March 2020

110

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15 March 2020

10

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15 March 2020

2434-2440

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15 March 2020

An open-label, single-arm, phase 2 trial of the Polo-like kinase inhibitor volasertib (BI 6727) in patients with locally advanced or metastatic urothelial cancer

1 reference

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21 June 2018

Phase i study of the Plk1 inhibitor BI 2536 administered intravenously on three consecutive days in advanced solid tumours

1 reference

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21 June 2018

NMS-P937, an orally available, specific small-molecule polo-like kinase 1 inhibitor with antitumor activity in solid and hematologic malignancies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021529

21 June 2018

TAK-960, a novel, orally available, selective inhibitor of polo-like kinase 1, shows broad-spectrum preclinical antitumor activity in multiple dosing regimens

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021529

21 June 2018

A phase I, dose-escalation study of the novel Polo-like kinase inhibitor volasertib (BI 6727) in patients with advanced solid tumours

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021529

21 June 2018

Polo-like kinase 1 inhibitors and their potential role in anticancer therapy, with a focus on NSCLC.

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21 June 2018

Phase I study of GSK461364, a specific and competitive Polo-like kinase 1 inhibitor, in patients with advanced solid malignancies

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21 June 2018

Multifaceted polo-like kinases: drug targets and antitargets for cancer therapy

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21 June 2018

BI 6727, a Polo-like kinase inhibitor with improved pharmacokinetic profile and broad antitumor activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021529

21 June 2018

Polo-like kinase (Plk)1 depletion induces apoptosis in cancer cells

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21 June 2018

New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada

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21 June 2018

A phase I pharmacokinetic study of HMN-214, a novel oral stilbene derivative with polo-like kinase-1-interacting properties, in patients with advanced solid tumors.

1 reference

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21 January 2018

An open-label, phase I study of the polo-like kinase-1 inhibitor, BI 2536, in patients with advanced solid tumors.

1 reference

https://api.crossref.org/works/10.1038%2FBJC.2014.195

21 January 2018

Phase I dose escalation and pharmacokinetic study of BI 2536, a novel Polo-like kinase 1 inhibitor, in patients with advanced solid tumors.

1 reference

https://api.crossref.org/works/10.1038%2FBJC.2014.195

21 January 2018

Polo‐like kinase 1 (PLK1) is overexpressed in primary colorectal cancers

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https://api.crossref.org/works/10.1038%2FBJC.2014.195

21 January 2018

Nonparametric Estimation from Incomplete Observations

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21 January 2018

Effect of RNA silencing of polo-like kinase-1 (PLK1) on apoptosis and spindle formation in human cancer cells

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12 December 2020

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10.1038/BJC.2014.195

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Europe PubMed Central

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15 March 2020

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15 March 2020

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15 March 2020

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