Positive feedback between transcriptional and kinase suppression in nematodes with extraordinary longevity and stress resistance (Q33428996)

26 July 2017

title

Positive feedback between transcriptional and kinase suppression in nematodes with extraordinary longevity and stress resistance (English)

1 reference

26 July 2017

Cagdaş Tazearslan

1

1 reference

26 July 2017

Srinivas Ayyadevara

series ordinal

2

1 reference

26 July 2017

Puneet Bharill

series ordinal

3

1 reference

26 July 2017

Robert J Shmookler Reis

series ordinal

4

1 reference

26 July 2017

language of work or name

1 reference

10 April 2009

1 reference

26 July 2017

1 reference

26 July 2017

volume

5

1 reference

26 July 2017

issue

4

1 reference

26 July 2017

page(s)

e1000452

1 reference

Creative Commons CC0 License

26 July 2017

copyright license

start time

10 April 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

0 references

cites work

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Tissue entrainment by feedback regulation of insulin gene expression in the endoderm of Caenorhabditis elegans

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Gene activities that mediate increased life span of C. elegans insulin-like signaling mutants

14 July 2018

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Remarkable longevity and stress resistance of nematode PI3K-null mutants

14 July 2018

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An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans

14 July 2018

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The C. elegans TGF-beta Dauer pathway regulates longevity via insulin signaling

14 July 2018

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Evolutionary conservation of regulated longevity assurance mechanisms

14 July 2018

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Two neurons mediate diet-restriction-induced longevity in C. elegans

14 July 2018

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14 July 2018

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14 July 2018

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Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans

14 July 2018

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p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans

14 July 2018

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Signalling through Class I PI3Ks in mammalian cells

14 July 2018

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Activated AKT/PKB signaling in C. elegans uncouples temporally distinct outputs of DAF-2/insulin-like signaling

14 July 2018

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The search for DAF-16/FOXO transcriptional targets: approaches and discoveries.

14 July 2018

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Quantitative trait loci define genes and pathways underlying genetic variation in longevity

14 July 2018

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Dual role of transcription factor FoxO1 in controlling hepatic insulin sensitivity and lipid metabolism

14 July 2018

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Effects of sex and insulin/insulin-like growth factor-1 signaling on performance in an associative learning paradigm in Caenorhabditis elegans

14 July 2018

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Long-term starvation and ageing induce AGE-1/PI 3-kinase-dependent translocation of DAF-16/FOXO to the cytoplasm

14 July 2018

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Inhibition of germline proliferation during C. elegans dauer development requires PTEN, LKB1 and AMPK signalling

14 July 2018

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Factors that control the tissue-specific transcription of the gene for phosphoenolpyruvate carboxykinase-C

14 July 2018

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Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans

14 July 2018

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JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16.

14 July 2018

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The plasticity of aging: insights from long-lived mutants

14 July 2018

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Broad spectrum detoxification: the major longevity assurance process regulated by insulin/IGF-1 signaling?

14 July 2018

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The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans

14 July 2018

1 reference

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Shared transcriptional signature in Caenorhabditis elegans Dauer larvae and long-lived daf-2 mutants implicates detoxification system in longevity assurance

14 July 2018

1 reference

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Preferential inhibition of Akt and killing of Akt-dependent cancer cells by rationally designed phosphatidylinositol ether lipid analogues

14 July 2018

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C. elegans SGK-1 is the critical component in the Akt/PKB kinase complex to control stress response and life span

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions

14 July 2018

1 reference

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SKN-1 links C. elegans mesendodermal specification to a conserved oxidative stress response

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

Genome-wide RNAi screening in Caenorhabditis elegans

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

Genetic loci modulating fitness and life span in Caenorhabditis elegans: categorical trait interval mapping in CL2a x Bergerac-BO recombinant-inbred worms.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

Insulin receptor substrate and p55 orthologous adaptor proteins function in the Caenorhabditis elegans daf-2/insulin-like signaling pathway

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

Membrane transport in Caenorhabditis elegans: an essential role for VPS34 at the nuclear membrane

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

Stress resistance as a determinate of C. elegans lifespan

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

Extending the lifespan of long-lived mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

Regulation of DAF-2 receptor signaling by human insulin and ins-1, a member of the unusually large and diverse C. elegans insulin gene family

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

Genetic mapping of quantitative trait loci governing longevity of Caenorhabditis elegans in recombinant-inbred progeny of a Bergerac-BO x RC301 interstrain cross

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

Diverse Caenorhabditis elegans genes that are upregulated in dauer larvae also show elevated transcript levels in long-lived, aged, or starved adults

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

The PTEN tumor suppressor homolog in Caenorhabditis elegans regulates longevity and dauer formation in an insulin receptor-like signaling pathway

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

An insulin-like signaling pathway affects both longevity and reproduction in Caenorhabditis elegans.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

Genetic analysis of the roles of daf-28 and age-1 in regulating Caenorhabditis elegans dauer formation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

The age-1 and daf-2 genes function in a common pathway to control the lifespan of Caenorhabditis elegans

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

Longevity-determining genes in Caenorhabditis elegans: chromosomal mapping of multiple noninteractive loci.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

A C. elegans mutant that lives twice as long as wild type

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

Genes that regulate both development and longevity in Caenorhabditis elegans

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

Temporal patterns of gene expression in the antenna of the adult Drosophila melanogaster

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

Interacting genes in nematode dauer larva formation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

A method for the isolation of longevity mutants in the nematode Caenorhabditis elegans and initial results

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

Three mutants that extend both mean and maximum life span of the nematode, Caenorhabditis elegans, define the age-1 gene.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

Non-ageing developmental variant of Caenorhabditis elegans

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2661368

Activation of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate

14 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000452

Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF-16.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000452

DAF-16 target genes that control C. elegans life-span and metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000452

SMK-1, an essential regulator of DAF-16-mediated longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000452

C. elegans 14-3-3 proteins regulate life span and interact with SIR-2.1 and DAF-16/FOXO.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000452

Molecular cloning and characterization of a new insulin/IGF-like peptide of the nematode Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000452

Aging networks in Caenorhabditis elegans: AMP-activated protein kinase (aak-2) links multiple aging and metabolism pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000452

DAF-16-dependent and independent expression targets of DAF-2 insulin receptor-like pathway in Caenorhabditis elegans include FKBPs

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000452

Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000452

daf-16 protects the nematode Caenorhabditis elegans during food deprivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000452

Lifespan and stress resistance of Caenorhabditis elegans are increased by expression of glutathione transferases capable of metabolizing the lipid peroxidation product 4-hydroxynonenal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000452

The p38 signal transduction pathway participates in the oxidative stress-mediated translocation of DAF-16 to Caenorhabditis elegans nuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000452

LET-60 RAS modulates effects of insulin/IGF-1 signaling on development and aging in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000452

PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000452

C. elegans SIR-2.1 interacts with 14-3-3 proteins to activate DAF-16 and extend life span

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000452

Overlapping and distinct functions for a Caenorhabditis elegans SIR2 and DAF-16/FOXO.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000452

Transcriptional targets of DAF-16 insulin signaling pathway protect C. elegans from extreme hypertonic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000452

Mutagenic effects of 4-hydroxynonenal triacetate, a chemically protected form of the lipid peroxidation product 4-hydroxynonenal, as assayed in L5178Y/Tk+/- mouse lymphoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000452

Increased life-span of age-1 mutants in Caenorhabditis elegans and lower Gompertz rate of aging

21 January 2018

1 reference

12 December 2020

Enrichment of regulatory motifs upstream of predicted DAF-16 targets

1 reference

12 December 2020

Testing evolutionary theories of aging

1 reference

12 December 2020

PtdIns(3,4,5)P3 gets its message across

1 reference

12 December 2020

Fitness cost of extended lifespan in Caenorhabditis elegans

1 reference

12 December 2020

10.1371/JOURNAL.PGEN.1000452

Identifiers

DOI

1 reference

26 July 2017

1 reference

26 July 2017

1 reference