LET-60 RAS modulates effects of insulin/IGF-1 signaling on development and aging in Caenorhabditis elegans (Q46704659)

24 December 2017

title

LET-60 RAS modulates effects of insulin/IGF-1 signaling on development and aging in Caenorhabditis elegans (English)

1 reference

24 December 2017

main subject

Caenorhabditis elegans

0 references

1 reference

3

1 reference

24 December 2017

Manoj Nanji

series ordinal

1

object named as

Manoj Nanji

1 reference

24 December 2017

author name string

Neil A Hopper

series ordinal

2

1 reference

24 December 2017

publication date

1 October 2005

1 reference

24 December 2017

published in

Aging Cell

1 reference

24 December 2017

volume

4

1 reference

24 December 2017

issue

5

1 reference

24 December 2017

page(s)

235-245

1 reference

24 December 2017

TheC. elegansG-protein-coupled receptor SRA-13 inhibits RAS/MAPK signalling during olfaction and vulval development

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

Fibroblast growth factor signaling in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

Caenorhabditis elegans SOS-1 is necessary for multiple RAS-mediated developmental signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

C. elegans cell-signalling gene sem-5 encodes a protein with SH2 and SH3 domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

Regulation of the Forkhead transcription factor AFX by Ral-dependent phosphorylation of threonines 447 and 451

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

Enhanced insulin signaling via Shc in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

A simple method for maintaining large, aging populations of Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

Interpreting interactions between treatments that slow aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

Regulation of the insulin-like developmental pathway of Caenorhabditis elegans by a homolog of the PTEN tumor suppressor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

let-60, a gene that specifies cell fates during C. elegans vulval induction, encodes a ras protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

C. elegans SGK-1 is the critical component in the Akt/PKB kinase complex to control stress response and life span

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

The Ras-MAPK pathway is important for olfaction in Caenorhabditis elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

The oncogenic RAS2(val19) mutation locks respiration, independently of PKA, in a mode prone to generate ROS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

The plasticity of aging: insights from long-lived mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

A C. elegans mutant that lives twice as long as wild type

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

The activation of phosphatidylinositol 3-kinase by Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

Direct control of the Forkhead transcription factor AFX by protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

Impaired Shc, Ras, and MAPK activation but normal Akt activation in FL5.12 cells expressing an insulin-like growth factor I receptor mutated at tyrosines 1250 and 1251.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

Ras: the other pro-aging pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

Evolution of Shc functions from nematode to human

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

Ras activation by insulin and epidermal growth factor through enhanced exchange of guanine nucleotides on p21ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

The PTEN tumor suppressor homolog in Caenorhabditis elegans regulates longevity and dauer formation in an insulin receptor-like signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

The C. elegans PTEN homolog, DAF-18, acts in the insulin receptor-like metabolic signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

Cell signaling by receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

Genetics of RAS signaling in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

Insulin receptor substrate and p55 orthologous adaptor proteins function in the Caenorhabditis elegans daf-2/insulin-like signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

Ras caught in another affair: the exchange factors for Ral.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

Ras is required for a limited number of cell fates and not for general proliferation in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

Phosphorylation and regulation of Raf by Akt (protein kinase B)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2005.00166.X

10.1111/J.1474-9726.2005.00166.X

21 January 2018

Identifiers

DOI

1 reference

24 December 2017

PubMed ID

16164423

1 reference

24 December 2017