Mechanistic approaches to predicting oral drug absorption (Q33432960)

26 July 2017

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title

Mechanistic approaches to predicting oral drug absorption (English)

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26 July 2017

Weili Huang

1

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26 July 2017

Sau Lawrence Lee

series ordinal

2

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26 July 2017

Lawrence X Yu

series ordinal

3

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26 July 2017

language of work or name

English

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publication date

21 April 2009

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26 July 2017

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26 July 2017

11

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26 July 2017

2

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26 July 2017

217-224

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https://scigraph.springernature.com/pub.10.1208/s12248-009-9098-z

26 July 2017

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cites work

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Toward a quantitative approach for the prediction of the fraction of dose absorbed using the absorption potential concept

21 June 2018

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21 June 2018

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Physicochemical characterization of five glyburide powders: a BCS based approach to predict oral absorption

31 October 2018

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31 October 2018

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31 October 2018

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In silico modeling of non-linear drug absorption for the P-gp substrate talinolol and of consequences for the resulting pharmacodynamic effect.

31 October 2018

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Analysis and prediction of absorption behavior for theophylline orally administered as powders based on gastrointestinal-transit-absorption (Gita) model

31 October 2018

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A physiologic model for simulating gastrointestinal flow and drug absorption in rats.

31 October 2018

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Segmental intestinal transporters and metabolic enzymes on intestinal drug absorption.

31 October 2018

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Analysis and prediction of absorption profile including hepatic first-pass metabolism of N-methyltyramine, a potent stimulant of gastrin release present in beer, after oral ingestion in rats by gastrointestinal-transit-absorption model.

31 October 2018

1 reference

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A new physiologically based, segregated-flow model to explain route-dependent intestinal metabolism.

31 October 2018

1 reference

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A compartmental absorption and transit model for estimating oral drug absorption.

31 October 2018

1 reference

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General solution for diffusion-controlled dissolution of spherical particles. 1. Theory.

31 October 2018

1 reference

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5'-Amino acid esters of antiviral nucleosides, acyclovir, and AZT are absorbed by the intestinal PEPT1 peptide transporter.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2691458

A mathematical model of drug absorption.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2691458

Absorption potential: estimating the fraction absorbed for orally administered compounds

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2691458

Predicting fraction dose absorbed in humans using a macroscopic mass balance approach

31 October 2018

1 reference

12 December 2020

On the Mechanism of Absorption of Drugs from the Gastrointestinal Tract

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12 December 2020

Carrier-mediated intestinal absorption of valacyclovir, the L-valyl ester prodrug of acyclovir: 1. Interactions with peptides, organic anions and organic cations in rats

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12 December 2020

P-glycoprotein increases from proximal to distal regions of human small intestine

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12 December 2020

Development of clinical dosage forms for a poorly water soluble drug I: Application of polyethylene glycol-polysorbate 80 solid dispersion carrier system

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12 December 2020

Comparison of human duodenum and Caco-2 gene expression profiles for 12,000 gene sequences tags and correlation with permeability of 26 drugs

1 reference

12 December 2020

Development and validation of a physiology-based model for the prediction of oral absorption in monkeys

1 reference

12 December 2020

Novel experimental parameters to quantify the modulation of absorptive and secretory transport of compounds by P-glycoprotein in cell culture models of intestinal epithelium

1 reference

12 December 2020

Mixing-tank model for predicting dissolution rate control or oral absorption

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12 December 2020

Prediction of oral absorption of griseofulvin, a BCS class II drug, based on GITA model: utilization of a more suitable medium for in-vitro dissolution study

1 reference

12 December 2020

Physicochemical model for dose-dependent drug absorption

1 reference

12 December 2020

Pharmacokinetic simulation of biowaiver criteria: the effects of gastric emptying, dissolution, absorption and elimination rates

1 reference

12 December 2020

Dissolution testing as a prognostic tool for oral drug absorption: dissolution behavior of glibenclamide

1 reference

12 December 2020

Intestinal transport of beta-lactam antibiotics: analysis of the affinity at the H+/peptide symporter (PEPT1), the uptake into Caco-2 cell monolayers and the transepithelial flux

1 reference

12 December 2020

Prediction of the plasma concentration profiles of orally administered drugs in rats on the basis of gastrointestinal transit kinetics and absorbability

1 reference

12 December 2020

Development of predictive pharmacokinetic simulation models for drug discovery

1 reference

12 December 2020

Regional jejunal perfusion, a new in vivo approach to study oral drug absorption in man

1 reference

12 December 2020

10.1208/S12248-009-9098-Z

Identifiers

DOI

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Dimensions Publication ID

26 July 2017

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26 July 2017

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