Monitoring compound integrity with cytochrome P450 assays and qHTS. (Q33456639)

26 July 2017

Monitoring compound integrity with cytochrome P450 assays and qHTS. (English)

1 reference

26 July 2017

5

1 reference

26 July 2017

6

Christopher P Austin

1 reference

26 July 2017

8

Douglas S Auld

1 reference

26 July 2017

4

Paul Shinn

1 reference

26 July 2017

3

Henrike Veith

1 reference

26 July 2017

1

Ryan MacArthur

1 reference

26 July 2017

William Leister

2

1 reference

PubMed ID

19483146

26 July 2017

James Inglese

series ordinal

7

1 reference

26 July 2017

29 May 2009

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Journal of Biomolecular Screening

26 July 2017

1 reference

26 July 2017

14

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26 July 2017

538-546

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26 July 2017

5

1 reference

Identification of pregnane X receptor ligands using time-resolved fluorescence resonance energy transfer and quantitative high-throughput screening

26 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430136

A robotic platform for quantitative high-throughput screening

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430136

Stability of screening compounds in wet DMSO.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430136

Compound Management for Quantitative High-Throughput Screening

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430136

High-throughput screening assays for the identification of chemical probes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430136

Screening library evolution through automation of solution preparation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430136

Building a pharmacological lexicon: small molecule discovery in academia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430136

Small-molecule screening: it takes a village...

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430136

Quality assessment and analysis of Biogen Idec compound library

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430136

Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430136

Luminogenic cytochrome P450 assays

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430136

In situ DMSO hydration measurements of HTS compound libraries

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430136

Nanoliter dispensing for uHTS using pin tools

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430136

History, evolution, and trends in compound management for high throughput screening

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430136

Studies of the relative stability of TFA adducts vs non-TFA analogues for combinatorial chemistry library members in DMSO in a repository compound collection

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430136

Studies on repository compound stability in DMSO under various conditions

21 June 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057109336954

Investigation of 3 industry-wide applied storage conditions for compound libraries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057109336954

The effect of room-temperature storage on the stability of compounds in DMSO.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057109336954

The effect of freeze/thaw cycles on the stability of compounds in DMSO.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057109336954

Compound library management

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057109336954

High throughput sonication: evaluation for compound solubilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057109336954

Examination of edge effects with different storage conditions of preplated dimethyl sulfoxide nanospots in ChemLib 1,536- and 3,456-well assay-ready plates

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057109336954

Development of a miniaturized 384-well high throughput screen for the detection of substrates of cytochrome P450 2D6 and 3A4 metabolism

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430136

Phase Diagram for the System Water–Dimethylsulphoxide

31 October 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057109336954

The minimum significant ratio: a statistical parameter to characterize the reproducibility of potency estimates from concentration-response assays and estimation by replicate-experiment studies

21 January 2018

1 reference

12 December 2020

Highly miniaturized formats for in vitro drug metabolism assays using vivid fluorescent substrates and recombinant human cytochrome P450 enzymes

1 reference

12 December 2020

Freezing Point Curve of Dimethyl Sulfoxide—Water Solutions

1 reference

12 December 2020

Bioluminescent assays for ADMET

1 reference

12 December 2020

Identifiers

DOI

10.1177/1087057109336954

1 reference

26 July 2017

1 reference

26 July 2017

1 reference

PubMed ID

19483146