Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection (Q33476165)

27 July 2017

title

Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection (English)

1 reference

27 July 2017

20

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Vincent Quivy

6

Vincent Quivy

1 reference

27 July 2017

27

Carine Van Lint

0 references

Allan Guiguen

4

Allan Guiguen

1 reference

27 July 2017

17

Yvan de Launoit

1 reference

27 July 2017

12

Emmanuelle Veithen

0 references

Arsène Burny

19

Arsène Burny

0 references

Georges Herbein

22

Georges Herbein

1 reference

27 July 2017

21

Stéphane De Wit

1 reference

27 July 2017

26

Nathan Clumeck

1 reference

27 July 2017

Yves Collette

24

0 references

Michel Moutschen

Michel Moutschen

18

0 references

Olivier Lambotte

25

Olivier Lambotte

1 reference

27 July 2017

23

Olivier Rohr

1 reference

27 July 2017

Sophie Reuse

1

1 reference

27 July 2017

Miriam Calao

2

1 reference

27 July 2017

Kabamba Kabeya

3

1 reference

27 July 2017

Jean-Stéphane Gatot

5

1 reference

27 July 2017

Caroline Vanhulle

7

1 reference

27 July 2017

Aurélia Lamine

8

1 reference

27 July 2017

Dolores Vaira

9

1 reference

27 July 2017

Dominique Demonte

10

1 reference

27 July 2017

Valérie Martinelli

11

1 reference

27 July 2017

Thomas Cherrier

13

1 reference

27 July 2017

Véronique Avettand

14

1 reference

27 July 2017

Solène Poutrel

15

1 reference

27 July 2017

Jacques Piette

16

1 reference

27 July 2017

language of work or name

English

0 references

publication date

30 June 2009

1 reference

27 July 2017

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27 July 2017

volume

4

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27 July 2017

issue

6

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27 July 2017

page(s)

e6093

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Creative Commons Attribution 4.0 International

27 July 2017

copyright license

start time

30 June 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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28 July 2018

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Variability in content of the anti-AIDS drug candidate prostratin in Samoan populations of Homalanthus nutans.

28 July 2018

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Valproic acid without intensified antiviral therapy has limited impact on persistent HIV infection of resting CD4+ T cells

28 July 2018

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Practical synthesis of prostratin, DPP, and their analogs, adjuvant leads against latent HIV

28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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Vorinostat: a new oral histone deacetylase inhibitor approved for cutaneous T-cell lymphoma

28 July 2018

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Structural ramification for acetyl-lysine recognition by the bromodomain of human BRG1 protein, a central ATPase of the SWI/SNF remodeling complex

28 July 2018

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Chromatin-associated regulation of HIV-1 transcription: implications for the development of therapeutic strategies

28 July 2018

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MS-275, a potent orally available inhibitor of histone deacetylases--the development of an anticancer agent

28 July 2018

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Discovery and development of SAHA as an anticancer agent

28 July 2018

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HIV genetic diversity: biological and public health consequences.

28 July 2018

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Recruitment of chromatin-modifying enzymes by CTIP2 promotes HIV-1 transcriptional silencing

28 July 2018

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Experimental approaches to the study of HIV-1 latency

28 July 2018

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High-frequency epigenetic repression and silencing of retroviruses can be antagonized by histone deacetylase inhibitors and transcriptional activators, but uniform reactivation in cell clones is restricted by additional mechanisms

28 July 2018

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Effects of prostratin on Cyclin T1/P-TEFb function and the gene expression profile in primary resting CD4+ T cells

28 July 2018

1 reference

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Transcriptional repression of human immunodeficiency virus type 1 by AP-4

28 July 2018

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Epigenetic therapy of cancer: past, present and future

28 July 2018

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Prostratin as a new therapeutic agent targeting HIV viral reservoirs

28 July 2018

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NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

SWI/SNF complex is essential for NRSF-mediated suppression of neuronal genes in human nonsmall cell lung carcinoma cell lines

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Molecular mechanisms of HIV-1 proviral latency

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Depletion of latent HIV-1 infection in vivo: a proof-of-concept study

28 July 2018

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Mechanisms of HIV receptor and co-receptor down-regulation by prostratin: role of conventional and novel PKC isoforms

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Dual role of prostratin in inhibition of infection and reactivation of human immunodeficiency virus from latency in primary blood lymphocytes and lymphoid tissue

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Administration of HDAC inhibitors to reactivate HIV-1 expression in latent cellular reservoirs: implications for the development of therapeutic strategies

28 July 2018

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Coaxing HIV-1 from resting CD4 T cells: histone deacetylase inhibition allows latent viral expression

28 July 2018

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Potent and selective inhibition of HIV and SIV by prostratin interacting with viral entry

28 July 2018

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Recruitment of SWI/SNF to the human immunodeficiency virus type 1 promoter

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Regulation of HIV-1 gene expression by histone acetylation and factor recruitment at the LTR promoter

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Potentiation of tumor necrosis factor-induced NF-kappa B activation by deacetylase inhibitors is associated with a delayed cytoplasmic reappearance of I kappa B alpha

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

HIV reproducibly establishes a latent infection after acute infection of T cells in vitro.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Histone deacetylases (HDACs): characterization of the classical HDAC family

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Synergistic activation of human immunodeficiency virus type 1 promoter activity by NF-kappaB and inhibitors of deacetylases: potential perspectives for the development of therapeutic strategies

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Counterregulation of chromatin deacetylation and histone deacetylase occupancy at the integrated promoter of human immunodeficiency virus type 1 (HIV-1) by the HIV-1 repressor YY1 and HIV-1 activator Tat

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

The challenge of viral reservoirs in HIV-1 infection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Histone deacetylase inhibitors as new cancer drugs

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

The site of HIV-1 integration in the human genome determines basal transcriptional activity and response to Tat transactivation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Ordered recruitment of chromatin modifying and general transcription factors to the IFN-beta promoter

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Mechanisms of action of valproate: a commentatory

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Functional differences between the long terminal repeat transcriptional promoters of human immunodeficiency virus type 1 subtypes A through G.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Actions of sodium valproate on the central nervous system.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

HIV-1 tat transcriptional activity is regulated by acetylation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Purified histone acetyltransferase complexes stimulate HIV-1 transcription from preassembled nucleosomal arrays

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Transcriptional activation of the integrated chromatin-associated human immunodeficiency virus type 1 promoter

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Mutations in the tat gene are responsible for human immunodeficiency virus type 1 postintegration latency in the U1 cell line

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Histone acetyltransferases regulate HIV-1 enhancer activity in vitro

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

HIV-1 latency due to the site of proviral integration

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Chromatin disruption in the promoter of human immunodeficiency virus type 1 during transcriptional activation.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Activation of primary human T-lymphocytes through CD2 plus CD28 adhesion molecules induces long-term nuclear expression of NF-kappa B.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Induction of fetal hemoglobin production in subjects with sickle cell anemia by oral sodium phenylbutyrate

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Cytokine-induced expression of HIV-1 in a chronically infected promonocyte cell line.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

DNase I-hypersensitive sites are associated with both long terminal repeats and with the intragenic enhancer of integrated human immunodeficiency virus type 1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

A nonpromoting phorbol from the samoan medicinal plant Homalanthus nutans inhibits cell killing by HIV-1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Suberoylanilide hydroxamic acid reactivates HIV from latently infected cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

A pervasive role of histone acetyltransferases and deacetylases in an NF-kappaB-signaling code

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Prolonged valproic acid treatment does not reduce the size of latent HIV reservoir

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Hexamethylbisacetamide and disruption of human immunodeficiency virus type 1 latency in CD4(+) T cells

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Confronting proviral HIV infection

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Decay of the HIV reservoir in patients receiving antiretroviral therapy for extended periods: implications for eradication of virus

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Stability of the latent reservoir for HIV-1 in patients receiving valproic acid

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Latency: the hidden HIV-1 challenge

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Prostratin induces HIV activation and downregulates HIV receptors in peripheral blood lymphocytes

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Prostratin antagonizes HIV latency by activating NF-kappaB.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Expression of latent HAART-persistent HIV type 1 induced by novel cellular activating agents

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

The lymphocyte HIV reservoir in patients on long-term HAART is a memory of virus evolution

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Molecular Characterization, Reactivation, and Depletion of Latent HIV

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Activation of latent HIV-1 expression by the potent anti-tumor promoter 12-deoxyphorbol 13-phenylacetate

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Histone deacetylase inhibitors potently repress CXCR4 chemokine receptor expression and function in acute lymphoblastic leukaemia

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Targeted derepression of the human immunodeficiency virus type 1 long terminal repeat by pyrrole-imidazole polyamides

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Effects of prostratin on T-cell activation and human immunodeficiency virus latency

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Prostratin: activation of latent HIV-1 expression suggests a potential inductive adjuvant therapy for HAART.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Inhibitor of histone deacetylation, depsipeptide (FR901228), in the treatment of peripheral and cutaneous T-cell lymphoma: a case report

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Promoter targeting of chromatin-modifying complexes.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Suppression of HIV replication in the resting CD4+ T cell reservoir by autologous CD8+ T cells: implications for the development of therapeutic strategies

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Crucial role of the amino-terminal tyrosine residue 42 and the carboxyl-terminal PEST domain of I kappa B alpha in NF-kappa B activation by an oxidative stress

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Antireplicative and anticytopathic activities of prostratin, a non-tumor-promoting phorbol ester, against human immunodeficiency virus (HIV).

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Triggering CD 28 molecules synergize with CD 2 (T 11.1 and T 11.2)-mediated T cell activation.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699633

Oral sodium phenylbutyrate therapy in homozygous beta thalassemia: a clinical trial

31 October 2018

1 reference

12 December 2020

Superinduction of IL-8 in T cells by HIV-1 Tat protein is mediated through NF-kappaB factors

1 reference

12 December 2020

Re-emergence of HIV after stopping therapy

1 reference

12 December 2020

The role of T3 surface molecules in the activation of human T cells: a two-stimulus requirement for IL 2 production reflects events occurring at a pre-translational level

1 reference

12 December 2020

The CD2 and CD28 adhesion molecules induce long-term autocrine proliferation of CD4+ T cells

1 reference

12 December 2020

No change to HIV-1 latency with valproate therapy

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0006093

Identifiers

DOI

1 reference

27 July 2017

0 references

1 reference

27 July 2017

1 reference