A peek into tropomyosin binding and unfolding on the actin filament (Q33486522)

27 July 2017

title

A peek into tropomyosin binding and unfolding on the actin filament (English)

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27 July 2017

1 reference

Abhishek Singh

1

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27 July 2017

Sarah E Hitchcock-Degregori

series ordinal

2

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27 July 2017

language of work or name

English

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publication date

24 July 2009

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27 July 2017

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27 July 2017

volume

4

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27 July 2017

issue

7

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27 July 2017

page(s)

e6336

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Creative Commons Attribution 4.0 International

27 July 2017

copyright license

start time

24 July 2009

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Structure of the N Terminus of a Nonmuscle α-Tropomyosin in Complex with the C Terminus: Implications for Actin Binding † ‡

21 June 2018

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21 June 2018

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Thermal unfolding of smooth muscle and nonmuscle tropomyosin alpha-homodimers with alternatively spliced exons

21 June 2018

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Structure of the mid-region of tropomyosin: bending and binding sites for actin

21 June 2018

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Regulation of muscle contraction by tropomyosin and troponin: how structure illuminates function

21 June 2018

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Tropomyosin isoforms: divining rods for actin cytoskeleton function

21 June 2018

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Intrinsically unstructured proteins and their functions

21 June 2018

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Effects of two familial hypertrophic cardiomyopathy mutations in alpha-tropomyosin, Asp175Asn and Glu180Gly, on the thermal unfolding of actin-bound tropomyosin

21 June 2018

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21 June 2018

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Defining the minimum size of a hydrophobic cluster in two-stranded alpha-helical coiled-coils: effects on protein stability

21 June 2018

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Local destabilization of the tropomyosin coiled coil gives the molecular flexibility required for actin binding

21 June 2018

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Functions of tropomyosin's periodic repeats

21 June 2018

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Structure and interactions of the carboxyl terminus of striated muscle alpha-tropomyosin: it is important to be flexible

21 June 2018

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The crystal structure of the C-terminal fragment of striated-muscle alpha-tropomyosin reveals a key troponin T recognition site

21 June 2018

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Disease-causing mutations in cardiac troponin T: identification of a critical tropomyosin-binding region

21 June 2018

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Vertebrate tropomyosin: distribution, properties and function

21 June 2018

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Deciphering the design of the tropomyosin molecule

21 June 2018

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Importance of internal regions and the overall length of tropomyosin for actin binding and regulatory function

21 June 2018

1 reference

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Coiled coils: a highly versatile protein folding motif

21 June 2018

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Crystal structure of tropomyosin at 7 Angstroms resolution

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710508

Intramolecular pyrene excimer fluorescence: a probe of proximity and protein conformational change

21 June 2018

1 reference

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Integral repeats and a continuous coiled coil are required for binding of striated muscle tropomyosin to the regulated actin filament

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710508

Requirement of amino-terminal modification for striated muscle alpha-tropomyosin function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710508

Spectroscopic Determination of Tryptophan and Tyrosine in Proteins*

21 June 2018

1 reference

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 June 2018

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Construction of an atomic model for tropomyosin and implications for interactions with actin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710508

Tropomyosin crystal structure and muscle regulation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710508

Alpha-tropomyosin gene organization. Alternative splicing of duplicated isotype-specific exons accounts for the production of smooth and striated muscle isoforms.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710508

The structure of the amino terminus of tropomyosin is critical for binding to actin in the absence and presence of troponin.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710508

Use of T7 RNA polymerase to direct expression of cloned genes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710508

Tropomyosin has discrete actin-binding sites with sevenfold and fourteenfold periodicities

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710508

Intramolecular crosslinking of tropomyosin via disulfide bond formation: evidence for chain register

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710508

The 14-fold periodicity in alpha-tropomyosin and the interaction with actin.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710508

Effects of an interchain disulfide bond on tropomyosin structure: Intrinsic fluorescence and circular dichroism studies

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710508

Close encounters of the third kind: disordered domains and the interactions of proteins.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710508

Conserved Asp-137 imparts flexibility to tropomyosin and affects function

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710508

The second half of the fourth period of tropomyosin is a key region for Ca(2+)-dependent regulation of striated muscle thin filaments.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710508

Stabilizing and destabilizing clusters in the hydrophobic core of long two-stranded alpha-helical coiled-coils

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710508

Mapping the functional domains within the carboxyl terminus of alpha-tropomyosin encoded by the alternatively spliced ninth exon.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710508

Interaction of tropomyosin-troponin with actin filaments.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710508

Sequence repeats in α-tropomyosin

31 October 2018

1 reference

12 December 2020

Analysis of the primary sequence of α-tropomyosin from rabbit skeletal muscle

1 reference

12 December 2020

Equilibrium of the actin-tropomyosin interaction

1 reference

12 December 2020

Fragments of rabbit striated muscle alpha-tropomyosin. II. Binding to troponin-T

1 reference

12 December 2020

Changes in actin lysine reactivities during polymerization detected using a competitive labeling method

1 reference

12 December 2020

Local structural changes in tropomyosin detected by a trypsin-probe method

1 reference

12 December 2020

Fluorescence studies of the conformation of pyrene-labeled tropomyosin: effects of F-actin and myosin subfragment 1

1 reference

12 December 2020

Excimer fluorescence of pyrenyliodoacetamide-labeled tropomyosin: a probe of the state of tropomyosin in reconstituted muscle thin filaments

1 reference

12 December 2020

Cooperative interactions between adjacent troponin-tropomyosin complexes may be transmitted through the actin filament

1 reference

12 December 2020

Thermodynamic analysis of the structural stability of the tetrameric oligomerization domain of p53 tumor suppressor

1 reference

12 December 2020

The structural stability of the co-chaperonin GroES

1 reference

12 December 2020

Dual requirement for flexibility and specificity for binding of the coiled-coil tropomyosin to its target, actin

1 reference

12 December 2020

Solution NMR structure of the junction between tropomyosin molecules: implications for actin binding and regulation

1 reference

12 December 2020

Crystal structures of tropomyosin: flexible coiled-coil

1 reference

12 December 2020

Tropomyosin's periods are quasi-equivalent for actin binding but have specific regulatory functions

1 reference

12 December 2020

Complexes of smooth muscle tropomyosin with F-actin studied by differential scanning calorimetry

1 reference

12 December 2020

Effects of tropomyosin internal deletions on thin filament function

1 reference

12 December 2020

Effects of troponin on thermal unfolding of actin-bound tropomyosin

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0006336

Identifiers

DOI

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27 July 2017

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27 July 2017

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