Citrus auraptene suppresses cyclin D1 and significantly delays N-methyl nitrosourea induced mammary carcinogenesis in female Sprague-Dawley rats (Q33488368)

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English	Citrus auraptene suppresses cyclin D1 and significantly delays N-methyl nitrosourea induced mammary carcinogenesis in female Sprague-Dawley rats	scientific article

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3 February 2020

Citrus auraptene suppresses cyclin D1 and significantly delays N-methyl nitrosourea induced mammary carcinogenesis in female Sprague-Dawley rats (English)

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3 February 2020

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ChEBI release 2020-05-28

Trifoliate orange

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Atalantia monophylla

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2H-1-Benzopyran-2-one, 7-[[(2E)-3,7-dimethyl-2,6-octadienyl]oxy]-

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1 reference

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Citrus wilsonii

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1 reference

7

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3 February 2020

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Prasad Krishnan

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3 February 2020

Karen J Yan

2

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3 February 2020

David Windler

3

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3 February 2020

Jesse Tubbs

4

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3 February 2020

Robert Grand

5

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3 February 2020

Benjamin D L Li

6

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3 February 2020

Jerry McLarty

8

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3 February 2020

Heather E Kleiner-Hancock

9

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3 February 2020

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29 July 2009

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3 February 2020

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https://bmccancer.biomedcentral.com/counter/pdf/10.1186/1471-2407-9-259

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19 March 2024

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Europe PubMed Central

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3 February 2020

9

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3 February 2020

259

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3 February 2020

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19 March 2024

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access restriction status

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Comparison of citrus coumarins on carcinogen-detoxifying enzymes in Nrf2 knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724550

21 June 2018

Tissue microarray analysis of eIF4E and its downstream effector proteins in human breast cancer

1 reference

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21 June 2018

Citrus compounds inhibit inflammation- and obesity-related colon carcinogenesis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724550

21 June 2018

Effects of naturally occurring coumarins on hepatic drug-metabolizing enzymes in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724550

21 June 2018

Protective effects of citrus nobiletin and auraptene in transgenic rats developing adenocarcinoma of the prostate (TRAP) and human prostate carcinoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724550

21 June 2018

Citrus auraptene targets translation of MMP-7 (matrilysin) via ERK1/2-dependent and mTOR-independent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724550

21 June 2018

Cancer-preventive anti-oxidants that attenuate free radical generation by inflammatory cells

1 reference

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21 June 2018

Naturally occurring coumarins inhibit 7,12-dimethylbenz[a]anthracene DNA adduct formation in mouse mammary gland

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724550

21 June 2018

Studies on coumarins and coumarin-related compounds to determine their therapeutic role in the treatment of cancer

1 reference

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21 June 2018

Cancer chemoprevention with dietary phytochemicals

1 reference

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21 June 2018

Further investigation of the modifying effect of various chemopreventive agents on apoptosis and cell proliferation in human colon cancer cells

1 reference

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21 June 2018

Oral administration of the citrus coumarin, isopimpinellin, blocks DNA adduct formation and skin tumor initiation by 7,12-dimethylbenz[a]anthracene in SENCAR mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724550

21 June 2018

Oral administration of naturally occurring coumarins leads to altered phase I and II enzyme activities and reduced DNA adduct formation by polycyclic aromatic hydrocarbons in various tissues of SENCAR mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724550

21 June 2018

Citrus auraptene inhibits chemically induced colonic aberrant crypt foci in male F344 rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724550

21 June 2018

Auraptene, a citrus coumarin, inhibits 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion in ICR mouse skin, possibly through suppression of superoxide generation in leukocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724550

21 June 2018

Preclinical efficacy evaluation of potential chemopreventive agents in animal carcinogenesis models: methods and results from the NCI Chemoprevention Drug Development Program.

1 reference

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21 June 2018

Comparative study of human and rat mammary tumorigenesis.

1 reference

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21 June 2018

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724550

21 June 2018

Apoptogenic activity of auraptene of Zanthoxylum schinifolium toward human acute leukemia Jurkat T cells is associated with ER stress-mediated caspase-8 activation that stimulates mitochondria-dependent or -independent caspase cascade.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-9-259

21 January 2018

Chemoprevention of 4-nitroquinoline 1-oxide-induced oral carcinogenesis by citrus auraptene in rats

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-9-259

21 January 2018

Dietary supplementation of the citrus antioxidant auraptene inhibits N,N-diethylnitrosamine-induced rat hepatocarcinogenesis

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-9-259

21 January 2018

Citrus auraptene suppresses azoxymethane-induced colonic preneoplastic lesions in C57BL/KsJ-db/db mice.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-9-259

21 January 2018

Dietary administration with prenyloxycoumarins, auraptene and collinin, inhibits colitis-related colon carcinogenesis in mice

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-9-259

21 January 2018

Auraptene decreases the activity of matrix metalloproteinases in dextran sulfate sodium-induced ulcerative colitis in ICR mice.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-9-259

21 January 2018

Rapid and convenient method for preparing aurapten-enriched product from hassaku peel oil: implications for cancer-preventive food additives

1 reference

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21 January 2018

Metabolism and absorption of auraptene (7-geranyloxylcoumarin) in male SD rats: comparison with 7-ethoxycoumarin

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-9-259

21 January 2018

Suppression of beta-catenin mutation by dietary exposure of auraptene, a citrus antioxidant, in N,N-diethylnitrosamine-induced hepatocellular carcinomas in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724550

31 October 2018

Citrus auraptene exerts dose-dependent chemopreventive activity in rat large bowel tumorigenesis: the inhibition correlates with suppression of cell proliferation and lipid peroxidation and with induction of phase II drug-metabolizing enzymes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724550

31 October 2018

Zingiberaceous and citrus constituents, 1'-acetoxychavicol acetate, zerumbone, auraptene, and nobiletin, suppress lipopolysaccharide-induced cyclooxygenase-2 expression in RAW264.7 murine macrophages through different modes of action

1 reference

https://pubmed.ncbi.nlm.nih.gov/19640308

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Studies on chemical constituents from fruits of Paliurus ramosissimus]

1 reference

https://pubmed.ncbi.nlm.nih.gov/19640308

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis by dietary feeding of auraptene

1 reference

https://pubmed.ncbi.nlm.nih.gov/19640308

12 December 2020

based on heuristic

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10.1186/1471-2407-9-259

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3 February 2020

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3 February 2020

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3 February 2020

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