Repression of RNA polymerase II elongation in vivo is critically dependent on the C-terminus of Spt5. (Q33501748)

27 July 2017

title

Repression of RNA polymerase II elongation in vivo is critically dependent on the C-terminus of Spt5. (English)

1 reference

27 July 2017

Hui Chen

1

1 reference

27 July 2017

Xavier Contreras

2

1 reference

27 July 2017

Yuki Yamaguchi

3

1 reference

27 July 2017

Hiroshi Handa

4

1 reference

27 July 2017

B Matija Peterlin

5

1 reference

27 July 2017

Su Guo

6

1 reference

27 July 2017

language of work or name

English

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publication date

9 September 2009

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27 July 2017

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27 July 2017

volume

4

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27 July 2017

issue

9

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27 July 2017

page(s)

e6918

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Creative Commons Attribution 4.0 International

27 July 2017

copyright license

start time

9 September 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Identification of Spt5 target genes in zebrafish development reveals its dual activity in vivo

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NELF-mediated stalling of Pol II can enhance gene expression by blocking promoter-proximal nucleosome assembly

21 June 2018

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NELF and GAGA factor are linked to promoter-proximal pausing at many genes in Drosophila

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735033

RNA polymerase is poised for activation across the genome

21 June 2018

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RNA polymerase stalling at developmental control genes in the Drosophila melanogaster embryo

21 June 2018

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AIRE recruits P-TEFb for transcriptional elongation of target genes in medullary thymic epithelial cells

21 June 2018

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A chromatin landmark and transcription initiation at most promoters in human cells

21 June 2018

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Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

21 June 2018

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Properties of RNA polymerase II elongation complexes before and after the P-TEFb-mediated transition into productive elongation.

21 June 2018

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Breaking barriers to transcription elongation

21 June 2018

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Controlling the elongation phase of transcription with P-TEFb

21 June 2018

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NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation

21 June 2018

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A negative elongation factor for human RNA polymerase II inhibits the anti-arrest transcript-cleavage factor TFIIS.

21 June 2018

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Zebrafish foggy/spt 5 is required for migration of facial branchiomotor neurons but not for their survival.

21 June 2018

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Npl3 is an antagonist of mRNA 3' end formation by RNA polymerase II.

21 June 2018

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A new paradigm in eukaryotic biology: HIV Tat and the control of transcriptional elongation

21 June 2018

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Modulating HIV-1 replication by RNA interference directed against human transcription elongation factor SPT5

21 June 2018

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Elongation by RNA polymerase II: the short and long of it

21 June 2018

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Locus-specific requirements for Spt5 in transcriptional activation and repression in Drosophila

21 June 2018

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The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote

21 June 2018

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Heat shock gene expression and function during zebrafish embryogenesis

21 June 2018

1 reference

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Regulation of RNA polymerase II transcription by sequence-specific DNA binding factors

21 June 2018

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Dynamics of human immunodeficiency virus transcription: P-TEFb phosphorylates RD and dissociates negative effectors from the transactivation response element

21 June 2018

1 reference

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In Vivo Evidence that Defects in the Transcriptional Elongation Factors RPB2, TFIIS, and SPT5 Enhance Upstream Poly(A) Site Utilization

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735033

NELF and DSIF cause promoter proximal pausing on the hsp70 promoter in Drosophila

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735033

Dual roles for Spt5 in pre-mRNA processing and transcription elongation revealed by identification of Spt5-associated proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735033

CDK-9/cyclin T (P-TEFb) is required in two postinitiation pathways for transcription in the C. elegans embryo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735033

Phosphorylation of the RNA polymerase II carboxyl-terminal domain by CDK9 is directly responsible for human immunodeficiency virus type 1 Tat-activated transcriptional elongation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735033

The elongation factors Pandora/Spt6 and Foggy/Spt5 promote transcription in the zebrafish embryo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735033

The peptidyl-prolyl isomerase Pin1 interacts with hSpt5 phosphorylated by Cdk9

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735033

A highly purified RNA polymerase II elongation control system

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735033

Positive transcription elongation factor B phosphorylates hSPT5 and RNA polymerase II carboxyl-terminal domain independently of cyclin-dependent kinase-activating kinase.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735033

High-resolution localization of Drosophila Spt5 and Spt6 at heat shock genes in vivo: roles in promoter proximal pausing and transcription elongation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735033

Spt5 and spt6 are associated with active transcription and have characteristics of general elongation factors in D. melanogaster

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735033

Transcription elongation and human disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735033

Domains in the SPT5 protein that modulate its transcriptional regulatory properties

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735033

Laser-induced gene expression in specific cells of transgenic zebrafish

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735033

Development of noradrenergic neurons in the zebrafish hindbrain requires BMP, FGF8, and the homeodomain protein soulless/Phox2a

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735033

Transcription elongation factor hSPT5 stimulates mRNA capping

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735033

NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735033

Structure and function of the human transcription elongation factor DSIF

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735033

Evidence that P-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription in vitro

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735033

Role of the human homolog of the yeast transcription factor SPT5 in HIV-1 Tat-activation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735033

DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735033

Stages of embryonic development of the zebrafish

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735033

RNA polymerase II interacts with the promoter region of the noninduced hsp70 gene in Drosophila melanogaster cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735033

Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene product

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735033

SPT5, an essential gene important for normal transcription in Saccharomyces cerevisiae, encodes an acidic nuclear protein with a carboxy-terminal repeat

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735033

Promoter melting and TFIID complexes on Drosophila genes in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735033

Characterization of the Schizosaccharomyces pombe Cdk9/Pch1 protein kinase: Spt5 phosphorylation, autophosphorylation, and mutational analysis

21 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0006918

P-TEFb-mediated phosphorylation of hSpt5 C-terminal repeats is critical for processive transcription elongation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0006918

A regulator of transcriptional elongation controls vertebrate neuronal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0006918

Interactions between fission yeast mRNA capping enzymes and elongation factor Spt5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0006918

Exploring functional relationships between components of the gene expression machinery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0006918

Molecular and genetic characterization of SPT4, a gene important for transcription initiation in Saccharomyces cerevisiae

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735033

10.1371/JOURNAL.PONE.0006918

31 October 2018

Identifiers

DOI

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27 July 2017

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1 reference

27 July 2017

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