Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells (Q33510340)

27 July 2017

Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells (English)

1 reference

27 July 2017

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Staphylococcus aureus

1 reference

Juliane Bubeck Wardenburg

inferred from title

author

5

object named as

Juliane Bubeck Wardenburg

1 reference

27 July 2017

Robin R Craven

1

1 reference

27 July 2017

Xi Gao

2

1 reference

27 July 2017

Irving C Allen

3

1 reference

27 July 2017

Denis Gris

4

1 reference

27 July 2017

Erin McElvania-Tekippe

6

1 reference

27 July 2017

Jenny P Ting

7

1 reference

27 July 2017

Joseph A Duncan

8

1 reference

27 July 2017

language of work or name

English

0 references

publication date

14 October 2009

1 reference

27 July 2017

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27 July 2017

4

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27 July 2017

10

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27 July 2017

e7446

1 reference

Creative Commons Attribution 4.0 International

27 July 2017

start time

14 October 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Membrane bound monomer of Staphylococcal alpha-hemolysin induces caspase activation and apoptotic cell death despite initiation of membrane repair pathway

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Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome

21 June 2018

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Anti-alpha-hemolysin monoclonal antibodies mediate protection against Staphylococcus aureus pneumonia

21 June 2018

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The inflammasomes: guardians of the body

21 June 2018

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The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

21 June 2018

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The role of virulence determinants in community-associated MRSA pathogenesis

21 June 2018

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The NLR gene family: a standard nomenclature

21 June 2018

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Vaccine protection against Staphylococcus aureus pneumonia

21 June 2018

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Poring over pores: alpha-hemolysin and Panton-Valentine leukocidin in Staphylococcus aureus pneumonia

21 June 2018

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Microbial pathogen-induced necrotic cell death mediated by the inflammasome components CIAS1/cryopyrin/NLRP3 and ASC.

21 June 2018

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Staphylococcus aureus Panton-Valentine leukocidin causes necrotizing pneumonia

21 June 2018

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Disease-associated mutations in CIAS1 induce cathepsin B-dependent rapid cell death of human THP-1 monocytic cells

21 June 2018

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Surface proteins and exotoxins are required for the pathogenesis of Staphylococcus aureus pneumonia

21 June 2018

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Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA

21 June 2018

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Cutting edge: ASC mediates the induction of multiple cytokines by Porphyromonas gingivalis via caspase-1-dependent and -independent pathways

21 June 2018

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Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1

21 June 2018

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CATERPILLERs, pyrin and hereditary immunological disorders

21 June 2018

1 reference

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Cryopyrin activates the inflammasome in response to toxins and ATP

21 June 2018

1 reference

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Gout-associated uric acid crystals activate the NALP3 inflammasome

21 June 2018

1 reference

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Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

21 June 2018

1 reference

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Severe community-onset pneumonia in healthy adults caused by methicillin-resistant Staphylococcus aureus carrying the Panton-Valentine leukocidin genes

21 June 2018

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NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder

21 June 2018

1 reference

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Cryopyrin-induced interleukin 1beta secretion in monocytic cells: enhanced activity of disease-associated mutants and requirement for ASC

21 June 2018

1 reference

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De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseases

21 June 2018

1 reference

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The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

21 June 2018

1 reference

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Mediator generation and signaling events in alveolar epithelial cells attacked by S. aureus alpha-toxin.

21 June 2018

1 reference

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alpha-Toxin is a mediator of Staphylococcus aureus-induced cell death and activates caspases via the intrinsic death pathway independently of death receptor signaling

21 June 2018

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Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome

21 June 2018

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Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components

21 June 2018

1 reference

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Alpha-toxin damages the air-blood barrier of the lung in a rat model of Staphylococcus aureus-induced pneumonia.

21 June 2018

1 reference

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Cutting edge: recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2

21 June 2018

1 reference

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Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2

21 June 2018

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Possible virulence factors of Staphylococcus aureus in a mouse septic model

21 June 2018

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Alpha-toxin and gamma-toxin jointly promote Staphylococcus aureus virulence in murine septic arthritis.

21 June 2018

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Channel-forming leucotoxins from Staphylococcus aureus cause severe inflammatory reactions in a rabbit eye model

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758589

Human endothelial cell activation and mediator release in response to the bacterial exotoxins Escherichia coli hemolysin and staphylococcal alpha-toxin.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758589

Site-directed mutagenesis of the alpha-toxin gene of Staphylococcus aureus: role of histidines in toxin activity in vitro and in a murine model

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758589

Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758589

Virulence of protein A-deficient and alpha-toxin-deficient mutants of Staphylococcus aureus isolated by allele replacement

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758589

Release of interleukin-1 beta associated with potent cytocidal action of staphylococcal alpha-toxin on human monocytes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758589

Roles of alpha-toxin and beta-toxin in virulence of Staphylococcus aureus for the mouse mammary gland

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758589

Staphylococcal alpha-toxin-induced vascular leakage in isolated perfused rabbit lungs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758589

Methicillin-ResistantS. aureusInfections among Patients in the Emergency Department

21 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0007446

Necrotizing fasciitis caused by community-associated methicillin-resistant Staphylococcus aureus in Los Angeles

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0007446

Natural history of community-acquired methicillin-resistant Staphylococcus aureus colonization and infection in soldiers

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0007446

Community-associated MRSA--resistance and virulence converge

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0007446

Pore-forming bacterial toxins potently induce release of nitric oxide in porcine endothelial cells.

21 January 2018

1 reference

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Staphylococcus aureus alpha-toxin induces apoptosis in peripheral blood mononuclear cells: role of endogenous tumour necrosis factor-alpha and the mitochondrial death pathway

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0007446

Staphylococcus aureus alpha-toxin-induced cell death: predominant necrosis despite apoptotic caspase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0007446

Disease-associated CIAS1 mutations induce monocyte death, revealing low-level mosaicism in mutation-negative cryopyrin-associated periodic syndrome patients

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19826485

12 December 2020

inferred from PubMed ID database lookup

Staphylococcal alpha-toxin synergistically enhances inflammation caused by bacterial components

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19826485

12 December 2020

inferred from PubMed ID database lookup

Stimulation of PAF-synthesis in pulmonary artery endothelial cells by Staphylococcus aureus alpha-toxin

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19826485

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1371/JOURNAL.PONE.0007446

1 reference

27 July 2017

0 references

1 reference

27 July 2017

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