Gene medicine for cancer treatment: commercially available medicine and accumulated clinical data in China (Q33516121)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19920899%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

review article

1 reference

title

Gene medicine for cancer treatment: commercially available medicine and accumulated clinical data in China (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19920899%20AND%20SRC:MED&resulttype=core&format=json

People's Republic of China

12 February 2020

main subject

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2

Hideaki Shimada

1 reference

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12 February 2020

author name string

Guangyu Ma

1

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12 February 2020

Kenzo Hiroshima

3

1 reference

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12 February 2020

Yuji Tada

4

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12 February 2020

Nobuo Suzuki

5

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12 February 2020

Masatoshi Tagawa

6

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12 February 2020

language of work or name

English

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publication date

6 February 2009

1 reference

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Drug Design, Development and Therapy

12 February 2020

published in

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12 February 2020

volume

2

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12 February 2020

page(s)

115-122

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Administration of PUMA adenovirus increases the sensitivity of esophageal cancer cells to anticancer drugs

12 February 2020

cites work

1 reference

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Current ideas about applications of heat shock proteins in vaccine design and immunotherapy

14 July 2018

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p53 promotes adenoviral replication and increases late viral gene expression

14 July 2018

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The effect of adenovirus expressing wild-type p53 on 5-fluorouracil chemosensitivity is related to p53 status in pancreatic cancer cell lines

14 July 2018

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Use of replicating oncolytic adenoviruses in combination therapy for cancer

14 July 2018

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Cooperative effect of adenoviral p53 gene therapy and standard chemotherapy in ovarian cancer cells independent of the endogenous p53 status

14 July 2018

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P53 down-regulates matrix metalloproteinase-1 by targeting the communications between AP-1 and the basal transcription complex

14 July 2018

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Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex.

14 July 2018

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The tumor suppressor p53 down-regulates glucose transporters GLUT1 and GLUT4 gene expression

14 July 2018

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Identification of Tcf-4 as a transcriptional target of p53 signalling

14 July 2018

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Down-regulation of sphingosine kinase-1 by DNA damage: dependence on proteases and p53.

14 July 2018

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Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

14 July 2018

1 reference

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Recombinant adenovirus p53 agent injection combined with radiotherapy in treatment of nasopharyngeal carcinoma: a phase II clinical trial

14 July 2018

1 reference

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Treatment of head and neck squamous cell carcinoma by recombinant adenovirus-p53 combined with radiotherapy: a phase II clinical trial of 42 cases

14 July 2018

1 reference

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Adenovirus-mediated wild-type p53 radiosensitizes human tumor cells by suppressing DNA repair capacity

14 July 2018

1 reference

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A broadly applicable, personalized heat shock protein-mediated oncolytic tumor vaccine

14 July 2018

1 reference

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Isolation of Temperature-sensitive p53 Mutations from a Comprehensive Missense Mutation Library

14 July 2018

1 reference

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Studies on the use of viruses in the treatment of carcinoma of the cervix

14 July 2018

1 reference

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Why did p53 gene therapy fail in ovarian cancer?

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761194

NKG2D ligands: unconventional MHC class I‐like molecules exploited by viruses and cancer

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761194

Pilot trial of intravenous infusion of a replication-selective adenovirus (ONYX-015) in combination with chemotherapy or IL-2 treatment in refractory cancer patients

14 July 2018

1 reference

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PAC1 phosphatase is a transcription target of p53 in signalling apoptosis and growth suppression

14 July 2018

1 reference

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p53AIP1 regulates the mitochondrial apoptotic pathway.

14 July 2018

1 reference

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p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas

14 July 2018

1 reference

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Introduction of mutant p53 into a wild-type p53-expressing glioma cell line confers sensitivity to Ad-p53-induced apoptosis

14 July 2018

1 reference

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Multidrug resistance (MDR) in cancer. Mechanisms, reversal using modulators of MDR and the role of MDR modulators in influencing the pharmacokinetics of anticancer drugs

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761194

Endogenous p53 gene status predicts the response of human squamous cell carcinomas to wild-type p53.

14 July 2018

1 reference

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Tissue and cell-specific expression of the p53-target genes: bax, fas, mdm2 and waf1/p21, before and following ionising irradiation in mice

14 July 2018

1 reference

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Adenovirus-mediated p53 gene transfer in sequence with cisplatin to tumors of patients with non-small-cell lung cancer

14 July 2018

1 reference

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p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs

14 July 2018

1 reference

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Cytotoxic effects of adenovirus-mediated wild-type p53 protein expression in normal and tumor mammary epithelial cells

14 July 2018

1 reference

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Replication of ONYX-015, a potential anticancer adenovirus, is independent of p53 status in tumor cells.

14 July 2018

1 reference

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Effects of p53-expressing adenovirus on the chemosensitivity and differentiation of anaplastic thyroid cancer cells

14 July 2018

1 reference

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Adenovirus-mediated p53 gene transfer in patients with advanced recurrent head and neck squamous cell carcinoma

14 July 2018

1 reference

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An adenovirus mutant that replicates selectively in p53-deficient human tumor cells

14 July 2018

1 reference

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Inhibition of p53 transactivation required for transformation by adenovirus early 1B protein

14 July 2018

1 reference

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Heat shock phenocopies E1B-55K late functions and selectively sensitizes refractory tumor cells to ONYX-015 oncolytic viral therapy

14 July 2018

1 reference

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Tumor-specific intravenous gene delivery using oncolytic adenoviruses

31 October 2018

1 reference

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Repeated intravesical instillations of an adenoviral vector in patients with locally advanced bladder cancer: a phase I study of p53 gene therapy

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761194

Hepatic arterial infusion of a replication-selective oncolytic adenovirus (dl1520): phase II viral, immunologic, and clinical endpoints

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761194

A phase I trial of CV706, a replication-competent, PSA selective oncolytic adenovirus, for the treatment of locally recurrent prostate cancer following radiation therapy

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761194

Adenovirus-mediated wild-type p53 gene transfer in patients receiving chemotherapy for advanced non-small-cell lung cancer: results of a multicenter phase II study

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761194

Administration of wild-type p53 adenoviral vector synergistically enhances the cytotoxicity of anti-cancer drugs in human lung cancer cells irrespective of the status of p53 gene

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761194

In vivo antitumor activity of ONYX-015 is influenced by p53 status and is augmented by radiotherapy

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761194

A phase I/II study of hepatic artery infusion with wtp53-CMV-Ad in metastatic malignant liver tumours

31 October 2018

1 reference

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p53 and brain tumors: from gene mutations to gene therapy

31 October 2018

1 reference

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In vitro evaluation of a p53-expressing adenovirus as an anti-cancer drug

31 October 2018

1 reference

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[Abscopal effect on metastatic tumor induced by oncolytic virus of H101 combining with local heating]

31 October 2018

1 reference

12 December 2020

Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1

1 reference

12 December 2020

Central role of p53 on regulation of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) expression in mammary carcinoma

1 reference

12 December 2020

Adenoviral delivery of p53 gene suppresses expression of collagenase-3 (MMP-13) in squamous carcinoma cells

1 reference

12 December 2020

1 reference

12 December 2020

Cellular and humoral immune responses to adenovirus and p53 protein antigens in patients following intratumoral injection of an adenovirus vector expressing wild-type. P53 (Ad-p53)

1 reference

12 December 2020

Adenovirus-mediated p53 gene transfer in advanced non-small-cell lung cancer

1 reference

12 December 2020

[Phase III randomized clinical trial of intratumoral injection of E1B gene-deleted adenovirus (H101) combined with cisplatin-based chemotherapy in treating squamous cell cancer of head and neck or esophagus]

1 reference

12 December 2020

Can China bring its own pipeline to the market?

1 reference

12 December 2020

CD200 is a novel p53-target gene involved in apoptosis-associated immune tolerance

1 reference

12 December 2020

Wild-Type p53 Gene Transfer Inhibits Invasion and Reduces Matrix Metalloproteinase-2 Levels in p53-Mutated Human Melanoma Cells

1 reference

12 December 2020

Identifiers

DOI

10.2147/DDDT.S3535

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19920899%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19920899%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

PubMed publication ID

19920899

1 reference