Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex. (Q34312488)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

title

Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

author name string

J I-Ju Leu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Patrick Dumont

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Michael Hafey

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Donna L George

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

publication date

11 April 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

volume

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

page(s)

443-450

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/ncb1123

27 December 2019

exact match

0 references

cites work

Mechanisms of p53-dependent apoptosis

1 reference

7 January 2021

Live or let die: the cell's response to p53

1 reference

7 January 2021

Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling

1 reference

7 January 2021

p53 has a direct apoptogenic role at the mitochondria

1 reference

7 January 2021

The codon 72 polymorphic variants of p53 have markedly different apoptotic potential

1 reference

7 January 2021

Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription

1 reference

7 January 2021

Is p53 polymorphism maintained by natural selection?

1 reference

7 January 2021

The Bcl2 family: regulators of the cellular life-or-death switch

1 reference

7 January 2021

Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a.

1 reference

7 January 2021

Two domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repression

1 reference

7 January 2021

Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

1 reference

7 January 2021

VDAC2 inhibits BAK activation and mitochondrial apoptosis

1 reference

7 January 2021

Cell damage-induced conformational changes of the pro-apoptotic protein Bak in vivo precede the onset of apoptosis

1 reference

7 January 2021

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

1 reference

7 January 2021

DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells

1 reference

7 January 2021

BCL-2 Selectively Interacts with the BID-induced Open Conformer of BAK, Inhibiting BAK Auto-oligomerization

1 reference

7 January 2021

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

1 reference

7 January 2021

BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

1 reference

7 January 2021

Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation

1 reference

7 January 2021

MCL-1, a member of the BLC-2 family, is induced rapidly in response to signals for cell differentiation or death, but not to signals for cell proliferation

1 reference

7 January 2021

MCL-1S, a splicing variant of the antiapoptotic BCL-2 family member MCL-1, encodes a proapoptotic protein possessing only the BH3 domain

1 reference

7 January 2021

MCL1 provides a window on the role of the BCL2 family in cell proliferation, differentiation and tumorigenesis

1 reference

7 January 2021

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

1 reference

7 January 2021

A transactivation-deficient mouse model provides insights into Trp53 regulation and function

1 reference

7 January 2021

Isolation and subfractionation of mitochondria from animal cells and tissue culture lines

1 reference

7 January 2021

Efficient folding of proteins with multiple disulfide bonds in the Escherichia coli cytoplasm

1 reference

7 January 2021

Bax in murine thymus is a soluble monomeric protein that displays differential detergent-induced conformations

1 reference

7 January 2021

Identifiers

DOI

10.1038/NCB1123

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

27 December 2019

0 references

1 reference