Notch2 signaling sensitizes endothelial cells to apoptosis by negatively regulating the key protective molecule survivin. (Q33518506)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20011512%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

title

Notch2 signaling sensitizes endothelial cells to apoptosis by negatively regulating the key protective molecule survivin (English)

1 reference

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15 January 2020

0 references

1 reference

1

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15 January 2020

Sophie Barillé-Nion

7

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15 January 2020

Beatrice Charreau

8

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15 January 2020

author name string

Julie Devalliere

2

1 reference

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15 January 2020

Mathias Chatelais

3

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15 January 2020

Flora Coulon

4

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15 January 2020

Céline Séveno

5

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15 January 2020

Mathilde Romagnoli

6

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15 January 2020

language of work or name

English

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publication date

11 December 2009

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15 January 2020

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15 January 2020

volume

4

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15 January 2020

issue

12

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15 January 2020

page(s)

e8244

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Creative Commons Attribution 4.0 International

15 January 2020

copyright license

start time

11 December 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Impaired Notch4 activity elicits endothelial cell activation and apoptosis: implication for transplant arteriosclerosis

1 reference

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The transcriptional coactivator Maml1 is required for Notch2-mediated marginal zone B-cell development

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Notch2 signaling induces apoptosis and inhibits human MDA-MB-231 xenograft growth

21 June 2018

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Loss of NOTCH2 positively predicts survival in subgroups of human glial brain tumors

21 June 2018

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Significant impact of survivin on myeloma cell growth.

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21 June 2018

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The adaptor molecule Lnk negatively regulates tumor necrosis factor-alpha-dependent VCAM-1 expression in endothelial cells through inhibition of the ERK1 and -2 pathways

21 June 2018

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Targeted therapy by disabling crossroad signaling networks: the survivin paradigm

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Target selectivity of vertebrate notch proteins. Collaboration between discrete domains and CSL-binding site architecture determines activation probability

21 June 2018

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Notch1 and notch2 have opposite effects on embryonal brain tumor growth

21 June 2018

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Notch activation induces endothelial cell cycle arrest and participates in contact inhibition: role of p21Cip1 repression

21 June 2018

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Notch4-induced inhibition of endothelial sprouting requires the ankyrin repeats and involves signaling through RBP-Jkappa

21 June 2018

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Notch4 inhibits endothelial apoptosis via RBP-Jkappa-dependent and -independent pathways

21 June 2018

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Survivin, versatile modulation of cell division and apoptosis in cancer

21 June 2018

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Activated Notch2 potentiates CD8 lineage maturation and promotes the selective development of B1 B cells.

21 June 2018

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The Anti-apoptotic Effect of Notch-1 Requires p56 -dependent, Akt/PKB-mediated Signaling in T Cells

21 June 2018

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The role of Notch in tumorigenesis: oncogene or tumour suppressor?

21 June 2018

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Notch2 is preferentially expressed in mature B cells and indispensable for marginal zone B lineage development

21 June 2018

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Notch signaling in vascular development

21 June 2018

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HES and HERP families: multiple effectors of the Notch signaling pathway

21 June 2018

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Endothelial activation: intracellular signaling pathways

21 June 2018

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Notch2 is involved in the overexpression of CD23 in B-cell chronic lymphocytic leukemia

21 June 2018

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Activated Notch4 inhibits angiogenesis: role of beta 1-integrin activation

21 June 2018

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 June 2018

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21 June 2018

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Notch signaling is essential for vascular morphogenesis in mice

21 June 2018

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21 June 2018

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21 June 2018

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31 October 2018

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31 October 2018

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Regulation of vein graft hyperplasia by survivin, an inhibitor of apoptosis protein.

31 October 2018

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The possible correlation of Notch-1 and Notch-2 with clinical outcome and tumour clinicopathological parameters in human breast cancer.

31 October 2018

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RhoA activation mediates phosphatidylinositol 3-kinase-dependent proliferation of human vascular endothelial cells: an alloimmune mechanism of chronic allograft nephropathy

31 October 2018

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Inhibitor of apoptosis protein survivin regulates vascular injury.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785888

Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785888

Notch signaling inhibits muscle cell differentiation through a CBF1-independent pathway.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785888

IL-11 protects human microvascular endothelium from alloinjury in vivo by induction of survivin expression

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20011512

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inhibition of endothelial cell proliferation by Notch1 signaling is mediated by repressing MAPK and PI3K/Akt pathways and requires MAML1

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20011512

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

1 reference

https://pubmed.ncbi.nlm.nih.gov/20011512

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0008244

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20011512%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20011512%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference