The study of xenobiotic-metabolizing enzymes and their role in toxicity in vivo using targeted gene disruption (Q33533990)

27 July 2017

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title

The study of xenobiotic-metabolizing enzymes and their role in toxicity in vivo using targeted gene disruption (English)

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27 July 2017

Gonzalez FJ

1

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27 July 2017

language of work or name

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1 December 1998

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27 July 2017

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27 July 2017

volume

102-103

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27 July 2017

page(s)

161-166

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Acetaminophen hepatotoxicity

27 July 2017

cites work

1 reference

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7 January 2021

Targeted disruption of retinoic acid receptor alpha (RAR alpha) and RAR gamma results in receptor-specific alterations in retinoic acid-mediated differentiation and retinoic acid metabolism

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7 January 2021

Role of cytochrome P4501A2 in chemical carcinogenesis: implications for human variability in expression and enzyme activity.

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Cytochromes P450 expression systems

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7 January 2021

Evolution of the P450 gene superfamily: animal-plant 'warfare', molecular drive and human genetic differences in drug oxidation

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7 January 2021

Biotransformation of caffeine, paraxanthine, theobromine and theophylline by cDNA-expressed human CYP1A2 and CYP2E1

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7 January 2021

Comparisons of catalytic selectivity of cytochrome P450 subfamily enzymes from different species

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7 January 2021

Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects

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Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

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7 January 2021

Role of CYP2E1 in the hepatotoxicity of acetaminophen

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7 January 2021

Cyp1a2(-/-) null mutant mice develop normally but show deficient drug metabolism

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Cytochrome P-4502E1: its physiological and pathological role

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Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT.

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7 January 2021

Disruption of the DT diaphorase (NQO1) gene in mice leads to increased menadione toxicity.

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7 January 2021

Acetaminophen activation by human liver cytochromes P450IIE1 and P450IA2

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7 January 2021

Chemoprotection against cancer by phase 2 enzyme induction

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Characterization of a polymorphism in NAD(P)H: quinone oxidoreductase (DT-diaphorase).

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7 January 2021

Protection against acetaminophen toxicity in CYP1A2 and CYP2E1 double-null mice

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7 January 2021

10.1016/S0378-4274(98)00302-6

Identifiers

DOI

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27 July 2017

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