E2F1 and E2F2 determine thresholds for antigen-induced T-cell proliferation and suppress tumorigenesis. (Q33551291)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11713289%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

title

E2F1 and E2F2 determine thresholds for antigen-induced T-cell proliferation and suppress tumorigenesis (English)

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3 December 2019

2

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3 December 2019

James Degregori

10

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3 December 2019

author name string

J W Zhu

1

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3 December 2019

L Gore

3

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3 December 2019

M Thompson

4

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3 December 2019

H Yang

5

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3 December 2019

Y Fujiwara

6

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3 December 2019

R D Cardiff

7

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3 December 2019

M Greenberg

8

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3 December 2019

S H Orkin

9

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3 December 2019

language of work or name

English

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publication date

1 December 2001

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Molecular and Cellular Biology

3 December 2019

published in

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3 December 2019

volume

21

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3 December 2019

page(s)

8547-8564

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issue

24

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The Rb/E2F pathway and cancer

3 December 2019

cites work

1 reference

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E2F3 contributes both to the inappropriate proliferation and to the apoptosis arising in Rb mutant embryos

21 June 2018

1 reference

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Role of the p53-homologue p73 in E2F1-induced apoptosis

21 June 2018

1 reference

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Role for the p53 homologue p73 in E2F-1-induced apoptosis

21 June 2018

1 reference

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E2F4 and E2F5 play an essential role in pocket protein-mediated G1 control

21 June 2018

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21 June 2018

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Loss of E2F4 activity leads to abnormal development of multiple cellular lineages

21 June 2018

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E2F4 is essential for normal erythrocyte maturation and neonatal viability

21 June 2018

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Limited overlapping roles of P15(INK4b) and P18(INK4c) cell cycle inhibitors in proliferation and tumorigenesis

21 June 2018

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E2f3 is critical for normal cellular proliferation

21 June 2018

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Immunology: improving on nature in the twenty-first century

21 June 2018

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Cbl-b regulates the CD28 dependence of T-cell activation.

21 June 2018

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CDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phase

21 June 2018

1 reference

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B cell development: signal transduction by antigen receptors and their surrogates.

21 June 2018

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Evidence for a rare prostate cancer-susceptibility locus at chromosome 1p36.

21 June 2018

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Key roles for E2F1 in signaling p53-dependent apoptosis and in cell division within developing tumors.

21 June 2018

1 reference

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CDK inhibitors p18(INK4c) and p27(Kip1) mediate two separate pathways to collaboratively suppress pituitary tumorigenesis

21 June 2018

1 reference

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Three-dimensional segregation of supramolecular activation clusters in T cells

21 June 2018

1 reference

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Helper T cell differentiation is controlled by the cell cycle

21 June 2018

1 reference

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The regulation of E2F by pRB-family proteins

21 June 2018

1 reference

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Cell division regulates the T cell cytokine repertoire, revealing a mechanism underlying immune class regulation

21 June 2018

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Positive versus negative signaling by lymphocyte antigen receptors

21 June 2018

1 reference

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A specific, nonproliferative role for E2F-5 in choroid plexus function revealed by gene targeting

21 June 2018

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p130 is dispensable in peripheral T lymphocytes: evidence for functional compensation by p107 and pRB.

21 June 2018

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Mutations of the Drosophila dDP, dE2F, and cyclin E genes reveal distinct roles for the E2F-DP transcription factor and cyclin E during the G1-S transition.

21 June 2018

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Mutations in Drosophila DP and E2F distinguish G1-S progression from an associated transcriptional program

21 June 2018

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Distinct roles for E2F proteins in cell growth control and apoptosis

21 June 2018

1 reference

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Cutting apart V(D)J recombination

21 June 2018

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E2F-4 switches from p130 to p107 and pRB in response to cell cycle reentry

21 June 2018

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Determination of lymphocyte division by flow cytometry

21 June 2018

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Oncogenic capacity of the E2F1 gene

21 June 2018

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Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo

21 June 2018

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RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

21 June 2018

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A common E2F-1 and p73 pathway mediates cell death induced by TCR activation.

21 June 2018

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The cell cycle inhibitor p21 controls T-cell proliferation and sex-linked lupus development.

31 October 2018

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Mechanisms of peripheral T cell tolerance

31 October 2018

1 reference

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Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection.

31 October 2018

1 reference

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Ikaros sets thresholds for T cell activation and regulates chromosome propagation

31 October 2018

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12 December 2020

Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b

1 reference

12 December 2020

E2F-1 functions in mice to promote apoptosis and suppress proliferation

1 reference

12 December 2020

Tumor induction and tissue atrophy in mice lacking E2F-1

1 reference

12 December 2020

Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/-)mice

1 reference

12 December 2020

Myc requires distinct E2F activities to induce S phase and apoptosis

1 reference

12 December 2020

A receptor/cytoskeletal movement triggered by costimulation during T cell activation

1 reference

12 December 2020

Molecular genetic analysis of familial neuroblastoma

1 reference

12 December 2020

Mutation of E2F2 in Mice Causes Enhanced T Lymphocyte Proliferation, Leading to the Development of Autoimmunity

1 reference

12 December 2020

A role for E2F1 in the induction of ARF, p53, and apoptosis during thymic negative selection

1 reference

12 December 2020

Deregulated expression of E2F1 induces hyperplasia and cooperates with ras in skin tumor development

1 reference

12 December 2020

Generation of normal lymphocyte populations by Rb-deficient embryonic stem cells

1 reference

12 December 2020

A role for E2F1 in the induction of apoptosis during thymic negative selection

1 reference

12 December 2020

Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos

1 reference

12 December 2020

10.1128/MCB.21.24.8547-8564.2001

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11713289%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

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3 December 2019

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