Animals as models of age-related macular degeneration: an imperfect measure of the truth (Q33552165)

28 July 2017

1 reference

title

Animals as models of age-related macular degeneration: an imperfect measure of the truth (English)

1 reference

28 July 2017

1 reference

C J Zeiss

1

1 reference

PubMed ID

20382825

28 July 2017

language of work or name

1 reference

9 April 2010

1 reference

28 July 2017

1 reference

28 July 2017

47

1 reference

28 July 2017

396-413

1 reference

28 July 2017

3

1 reference

A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Stargardt macular dystrophy

28 July 2017

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

An animal model of age-related macular degeneration in senescent Ccl-2- or Ccr-2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

A role for local inflammation in the formation of drusen in the aging eye.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Pigment epithelium-derived factor (PEDF) and vascular endothelial growth factor (VEGF) in aged human choroid and eyes with age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Bruch's membrane change with age

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Polarized vascular endothelial growth factor secretion by human retinal pigment epithelium and localization of vascular endothelial growth factor receptors on the inner choriocapillaris. Evidence for a trophic paracrine relation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Immunotherapy for choroidal neovascularization in a laser-induced mouse model simulating exudative (wet) macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

HTRA1 variant confers similar risks to geographic atrophy and neovascular age-related macular degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Gene therapy for ocular neovascularization

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Ccl2/Cx3cr1-deficient mice: an animal model for age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Intravitreal triamcinolone acetonide inhibits choroidal neovascularization in a laser-treated rat model

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Complement factor H deficiency in aged mice causes retinal abnormalities and visual dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

The squirrel monkey: characterization of a new-world primate model of experimental choroidal neovascularization and comparison with the macaque.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Anastomotic vessels remain viable after photodynamic therapy in primate models of choroidal neovascularization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Macular disease in related rhesus monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

HTRA1 promoter polymorphism in wet age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Evidence for association between multiple complement pathway genes and AMD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Macular degeneration in a patient with aceruloplasminemia, a disease associated with retinal iron overload

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Quantitative image analysis of laser-induced choroidal neovascularization in rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Complement factor H polymorphism and age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Macular degeneration in rhesus monkey (Macaca mulatta)

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Degenerative Changes in Maculas of Rhesus Monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Cigarette smoke-related oxidants and the development of sub-RPE deposits in an experimental animal model of dry AMD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Antioxidant supplements to prevent or slow down the progression of AMD: a systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Variation near complement factor I is associated with risk of advanced AMD

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Rhesus monkeys and humans share common susceptibility genes for age-related macular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Chronic cigarette smoke causes oxidative damage and apoptosis to retinal pigmented epithelial cells in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

The role of human HtrA1 in arthritic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Chemokines, a family of chemotactic cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Ceruloplasmin/hephaestin knockout mice model morphologic and molecular features of AMD

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Disruption of ceruloplasmin and hephaestin in mice causes retinal iron overload and retinal degeneration with features of age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Complement factor H variant increases the risk of age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Expression of VLDLR in the retina and evolution of subretinal neovascularization in the knockout mouse model's retinal angiomatous proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

A common CFH haplotype, with deletion of CFHR1 and CFHR3, is associated with lower risk of age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Drusen, choroidal neovascularization, and retinal pigment epithelium dysfunction in SOD1-deficient mice: a model of age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Susceptibility genes for age-related maculopathy on chromosome 10q26

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Complement activation and inflammatory processes in Drusen formation and age related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Individuals homozygous for the age-related macular degeneration risk-conferring variant of complement factor H have elevated levels of CRP in the choroid

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

SOD2 knockdown mouse model of early AMD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Lipofuscin accumulation, abnormal electrophysiology, and photoreceptor degeneration in mutant ELOVL4 transgenic mice: a model for macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Overview of progress in the epidemiology of age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

The epidemiology of age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Complement factor H polymorphism in age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

The APO(*)E3-Leiden mouse as an animal model for basal laminar deposit

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

LOC387715/HTRA1 variants in polypoidal choroidal vasculopathy and age-related macular degeneration in a Japanese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Clinicopathological correlation of deep retinal vascular anomalous complex in age related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Small molecule RPE65 antagonists limit the visual cycle and prevent lipofuscin formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Apolipoprotein E allele-dependent pathogenesis: a model for age-related retinal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Variation in complement factor 3 is associated with risk of age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Mutations in RPE65 cause Leber's congenital amaurosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Biosynthesis of a major lipofuscin fluorophore in mice and humans with ABCR-mediated retinal and macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Fibulin-5/DANCE is essential for elastogenesis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Drusen complement components C3a and C5a promote choroidal neovascularization

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

HtrA1 serine protease inhibits signaling mediated by Tgfbeta family proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Increased expression of VEGF in retinal pigmented epithelial cells is not sufficient to cause choroidal neovascularization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Immunopathological aspects of age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Translational mini-review series on complement factor H: renal diseases associated with complement factor H: novel insights from humans and animals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Progressive age-related changes similar to age-related macular degeneration in a transgenic mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Inflammation in dry age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

The human complement factor H: functional roles, genetic variations and disease associations

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Immunological protein expression profile in Ccl2/Cx3cr1 deficient mice with lesions similar to age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Increased expression of vascular endothelial growth factor associated with accumulation of lipids in Bruch's membrane of LDL receptor knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Subretinal neovascularization after argon laser photocoagulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Subretinal neovascularization. Natural history of an experimental model

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Intrachoroidal neovascularization in transgenic mice overexpressing vascular endothelial growth factor in the retinal pigment epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Association between C-reactive protein and age-related macular degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Dietary fat and risk for advanced age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Investigation of laser-induced choroidal neovascularization in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Regulation of complement activation by C-reactive protein: targeting of the inhibitory activity of C4b-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

A2E, a byproduct of the visual cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

The retinal pigment epithelium in visual function

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Association between apolipoprotein E polymorphisms and age-related macular degeneration: A HuGE review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Contribution of VEGF and PEDF to choroidal angiogenesis: a need for balanced expressions

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Deficiency of the Cockayne syndrome B (CSB) gene aggravates the genomic instability caused by endogenous oxidative DNA base damage in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Early-onset macular degeneration with drusen in a cynomolgus monkey (Macaca fascicularis) pedigree: exclusion of 13 candidate genes and loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Blood pressure, atherosclerosis, and the incidence of age-related maculopathy: the Rotterdam Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Inhibitors of vascular endothelial growth factor (VEGF) in the management of neovascular age-related macular degeneration: a review of current practice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Biomarkers of cardiovascular disease as risk factors for age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Autophagy and exosomes in the aged retinal pigment epithelium: possible relevance to drusen formation and age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Insights into the function of Rim protein in photoreceptors and etiology of Stargardt's disease from the phenotype in abcr knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Lipofuscin and Macular Degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Toll-like receptor 3 and geographic atrophy in age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Complement C3 variant and the risk of age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Current concepts in the pathogenesis of age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Proliferation of microglia, but not photoreceptors, in the outer nuclear layer of the rd-1 mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Toll-like receptor 4 deficiency causes pulmonary emphysema.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

Complement and diseases: defective alternative pathway control results in kidney and eye diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

The R345W mutation in EFEMP1 is pathogenic and causes AMD-like deposits in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985809359598

21 January 2018

Identifiers

DOI

10.1177/0300985809359598

1 reference

28 July 2017

1 reference

PubMed ID

20382825