Interferon gamma attenuates insulin signaling, lipid storage, and differentiation in human adipocytes via activation of the JAK/STAT pathway. (Q33553780)

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English	Interferon gamma attenuates insulin signaling, lipid storage, and differentiation in human adipocytes via activation of the JAK/STAT pathway.	scientific article

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Interferon gamma attenuates insulin signaling, lipid storage, and differentiation in human adipocytes via activation of the JAK/STAT pathway (English)

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Fiona C McGillicuddy

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Muredach P. Reilly

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Elise H Chiquoine

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Christine C Hinkle

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Roy J Kim

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Emer M Smyth

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23 September 2009

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Journal of Biological Chemistry

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31936-31944

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8 February 2020

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

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Interferon-gamma, a Th1 cytokine, regulates fat inflammation: a role for adaptive immunity in obesity

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Interferon regulatory factors are transcriptional regulators of adipogenesis

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Adipokines: the missing link between insulin resistance and obesity.

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Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects

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SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2

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Role of peroxisome proliferator-activated receptor-gamma in maintenance of the characteristics of mature 3T3-L1 adipocytes

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21 June 2018

SOCS-3 inhibits insulin signaling and is up-regulated in response to tumor necrosis factor-alpha in the adipose tissue of obese mice

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1 reference

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12 December 2020

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8 February 2020

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