Anti-tumor activity of olaparib, a poly (ADP-ribose) polymerase (PARP) inhibitor, in cultured endometrial carcinoma cells (Q33557916)

28 July 2017

Anti-tumor activity of olaparib, a poly (ADP-ribose) polymerase (PARP) inhibitor, in cultured endometrial carcinoma cells (English)

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28 July 2017

endometrial carcinoma

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1 reference

Kazunori Nagasaka

14

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Osamu Wada-Hiraike

object named as

Osamu Wada-Hiraike

4

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Yuji Ikeda

3

object named as

Yuji Ikeda

1 reference

28 July 2017

1

Aki Miyasaka

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28 July 2017

2

Katsutoshi Oda

1 reference

28 July 2017

5

Tomoko Kashiyama

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28 July 2017

11

Kenbun Sone

1 reference

28 July 2017

16

Takahide Arimoto

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28 July 2017

17

Shunsuke Nakagawa

1 reference

28 July 2017

18

Hiroyuki Kuramoto

1 reference

28 July 2017

21

Kei Kawana

1 reference

28 July 2017

22

Yutaka Osuga

1 reference

28 July 2017

23

Tomoyuki Fujii

1 reference

28 July 2017

Atsushi Enomoto

6

1 reference

28 July 2017

Noriko Hosoya

7

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28 July 2017

Takahiro Koso

8

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28 July 2017

Tomohiko Fukuda

9

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28 July 2017

Kanako Inaba

10

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28 July 2017

Yuriko Uehara

12

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28 July 2017

Reiko Kurikawa

13

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28 July 2017

Yoko Matsumoto

15

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28 July 2017

Kiyoshi Miyagawa

19

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28 July 2017

Tetsu Yano

20

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28 July 2017

language of work or name

English

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publication date

13 March 2014

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28 July 2017

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28 July 2017

14

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28 July 2017

179

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https://scigraph.springernature.com/pub.10.1186/1471-2407-14-179

28 July 2017

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cites work

Olaparib: a promising PARP inhibitor in ovarian cancer therapy

1 reference

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PARP inhibition sensitizes to low dose-rate radiation TMPRSS2-ERG fusion gene-expressing and PTEN-deficient prostate cancer cells

21 June 2018

1 reference

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RAD51C-deficient cancer cells are highly sensitive to the PARP inhibitor olaparib

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007824

Synergistic effect of olaparib with combination of cisplatin on PTEN-deficient lung cancer cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007824

Differential anti-proliferative activities of poly(ADP-ribose) polymerase (PARP) inhibitors in triple-negative breast cancer cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007824

Genotype-dependent efficacy of a dual PI3K/mTOR inhibitor, NVP-BEZ235, and an mTOR inhibitor, RAD001, in endometrial carcinomas

21 June 2018

1 reference

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21 June 2018

Cancer statistics, 2012

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PTEN deletion in prostate cancer cells does not associate with loss of RAD51 function: implications for radiotherapy and chemotherapy

21 June 2018

1 reference

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PARP inhibitors in BRCA gene-mutated ovarian cancer and beyond

21 June 2018

1 reference

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Synthetic lethality of PARP inhibition in cancers lacking BRCA1 and BRCA2 mutations

21 June 2018

1 reference

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Multifunctional transcription factor TFII-I is an activator of BRCA1 function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007824

PTEN deficiency in endometrioid endometrial adenocarcinomas predicts sensitivity to PARP inhibitors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007824

PTEN loss compromises homologous recombination repair in astrocytes: implications for glioblastoma therapy with temozolomide or poly(ADP-ribose) polymerase inhibitors.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007824

ATM deficiency sensitizes mantle cell lymphoma cells to poly(ADP-ribose) polymerase-1 inhibitors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007824

Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007824

PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007824

Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007824

The oncogenic mutation in the pleckstrin homology domain of AKT1 in endometrial carcinomas

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007824

PIK3CA cooperates with other phosphatidylinositol 3'-kinase pathway mutations to effect oncogenic transformation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007824

4-[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one: a novel bioavailable inhibitor of poly(ADP-ribose) polymerase-1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007824

Mechanism of eukaryotic homologous recombination

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007824

Essential role for nuclear PTEN in maintaining chromosomal integrity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007824

High frequency of coexistent mutations of PIK3CA and PTEN genes in endometrial carcinoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007824

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007824

Lack of PTEN sequesters CHK1 and initiates genetic instability.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007824

Rad51 recombinase and recombination mediators

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007824

Analysis of microsatellite instability and loss of heterozygosity in uterine endometrial adenocarcinoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007824

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

21 June 2018

1 reference

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Establishment and characterization of human endometrial cancer cell lines

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007824

The yield of DNA double-strand breaks produced intracellularly by ionizing radiation: a review

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007824

Role of poly(ADP-ribose) formation in DNA repair

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007824

Ablation of PARP-1 does not interfere with the repair of DNA double-strand breaks, but compromises the reactivation of stalled replication forks

21 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2F1471-2407-14-179

Genome-wide single nucleotide polymorphism arrays as a diagnostic tool in patients with synchronous endometrial and ovarian cancer.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2F1471-2407-14-179

PTEN methylation is associated with advanced stage and microsatellite instability in endometrial carcinoma

21 January 2018

1 reference

12 December 2020

K-ras activation in premalignant and malignant epithelial lesions of the human uterus

1 reference

12 December 2020

Allelic loss of sequences from the long arm of chromosome 10 and replication errors in endometrial cancers

1 reference

12 December 2020

PTEN loss inhibits CHK1 to cause double stranded-DNA breaks in cells

1 reference

12 December 2020

Exploiting the DNA Repair Defect in BRCA Mutant Cells in the Design of New Therapeutic Strategies for Cancer

1 reference

12 December 2020

Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly(ADP-ribose) polymerase inhibition

1 reference

12 December 2020

Treatment with olaparib in a patient with PTEN-deficient endometrioid endometrial cancer

1 reference

12 December 2020

Identifiers

DOI

10.1186/1471-2407-14-179

1 reference

Dimensions Publication ID

28 July 2017

1 reference

https://scigraph.springernature.com/pub.10.1186/1471-2407-14-179

9 September 2019

1 reference

28 July 2017

1 reference