Isoproterenol-induced FKBP12.6/12 downregulation is modulated by ETA and ETB receptors and reversed by argirhein, a derivative of rhein (Q33565656)

28 July 2017

title

Isoproterenol-induced FKBP12.6/12 downregulation is modulated by ETA and ETB receptors and reversed by argirhein, a derivative of rhein (English)

1 reference

28 July 2017

Tao Xi

3

0 references

author name string

Guo-lin Zhang

1

1 reference

28 July 2017

De-zai Dai

2

1 reference

28 July 2017

Xiao-dong Cong

4

1 reference

28 July 2017

Yun Zhang

5

1 reference

28 July 2017

Yin Dai

6

1 reference

28 July 2017

publication date

1 February 2011

1 reference

Acta Pharmacologica Sinica

28 July 2017

published in

1 reference

28 July 2017

volume

32

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28 July 2017

issue

2

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28 July 2017

page(s)

223-229

1 reference

Characterization of a novel mutation in the cardiac ryanodine receptor that results in catecholaminergic polymorphic ventricular tachycardia

28 July 2017

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Endothelin receptor antagonist CPU0213 and vitamin E reverse downregulation of FKBP12.6 and SERCA2a: a role of hyperphosphorylation of PKCepsilon

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Upregulation of leptin pathway correlates with abnormal expression of SERCA2a, phospholamban and the endothelin pathway in heart failure and reversal by CPU86017.

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21 June 2018

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FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death

21 June 2018

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21 June 2018

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21 January 2018

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Downregulated FKBP12.6 expression and upregulated endothelin signaling contribute to elevated diastolic calcium and arrhythmogenesis in rat cardiomyopathy produced by l-thyroxin

21 January 2018

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21 January 2018

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Diacerhein downregulate proinflammatory cytokines expression and decrease the autoimmune diabetes frequency in nonobese diabetic (NOD) mice.

21 January 2018

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The separate roles of endothelin receptors participate in remodeling of matrix metalloproteinase and connexin 43 of cardiac fibroblasts in maladaptive response to isoproterenol

21 January 2018

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Reversal of isoproterenol-induced downregulation of phospholamban and FKBP12.6 by CPU0213-mediated antagonism of endothelin receptors

21 January 2018

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Endothelin receptors, localized in sympathetic nerve terminals of the heart, modulate norepinephrine release and reperfusion arrhythmias

21 January 2018

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Rhein improves renal lesion and ameliorates dyslipidemia in db/db mice with diabetic nephropathy

21 January 2018

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Combined therapy of rhein and benazepril on the treatment of diabetic nephropathy in db/db mice

21 January 2018

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Rhein, the metabolite of diacerhein, reduces the proliferation of osteoarthritic chondrocytes and synoviocytes without inducing apoptosis

21 January 2018

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Inflammatory factors that contribute to upregulation of ERG and cardiac arrhythmias are suppressed by CPU86017, a class III antiarrhythmic agent

21 January 2018

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21 January 2018

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Stress-induced cardiac insufficiency relating to abnormal leptin and FKBP12.6 is ameliorated by CPU0213, an endothelin receptor antagonist, which is not affected by the CYP3A suppressing effect of erythromycin.

21 January 2018

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Rhein, a diacerhein-derived metabolite, modulates the expression of matrix degrading enzymes and the cell proliferation of articular chondrocytes by inhibiting ERK and JNK-AP-1 dependent pathways.

31 October 2018

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Rhein inhibits liver fibrosis induced by carbon tetrachloride in rats.

31 October 2018

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Up-regulated inflammatory factors endothelin, NFkappaB, TNFalpha and iNOS involved in exaggerated cardiac arrhythmias in l-thyroxine-induced cardiomyopathy are suppressed by darusentan in rats

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21293474

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Arrhythmogenic cardiomyopathy in a patient with Noonan syndrome

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21293474

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/APS.2010.177

1 reference

Dimensions Publication ID

28 July 2017

0 references

1 reference

28 July 2017

1 reference