The Notch effector Hey1 associates with myogenic target genes to repress myogenesis. (Q33569692)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19917614%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

title

The Notch effector Hey1 associates with myogenic target genes to repress myogenesis (English)

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12 February 2020

1

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12 February 2020

author name string

Shara Kabak

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19917614%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Tom Kadesch

series ordinal

3

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12 February 2020

language of work or name

English

0 references

publication date

16 November 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19917614%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

12 February 2020

published in

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12 February 2020

volume

285

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12 February 2020

issue

2

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12 February 2020

page(s)

1249-1258

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Ski regulates muscle terminal differentiation by transcriptional activation of Myog in a complex with Six1 and Eya3

12 February 2020

cites work

1 reference

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Integrated regulation of Toll-like receptor responses by Notch and interferon-gamma pathways

14 July 2018

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Inhibition of myogenesis by Notch: evidence for multiple pathways

14 July 2018

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A highly conserved molecular switch binds MSY-3 to regulate myogenin repression in postnatal muscle

14 July 2018

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Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochlea

14 July 2018

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The Notch signaling pathway controls the size of the ocular lens by directly suppressing p57Kip2 expression

14 July 2018

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Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch

14 July 2018

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Notch directly regulates Gata3 expression during T helper 2 cell differentiation

14 July 2018

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Detection of in vivo protein-DNA interactions using DamID in mammalian cells

14 July 2018

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RBP-J (Rbpsuh) is essential to maintain muscle progenitor cells and to generate satellite cells

14 July 2018

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Combined loss of Hey1 and HeyL causes congenital heart defects because of impaired epithelial to mesenchymal transition

14 July 2018

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Hesr1 and Hesr2 regulate atrioventricular boundary formation in the developing heart through the repression of Tbx2

14 July 2018

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Premature myogenic differentiation and depletion of progenitor cells cause severe muscle hypotrophy in Delta1 mutants

14 July 2018

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Developmental patterning of the cardiac atrioventricular canal by Notch and Hairy-related transcription factors

14 July 2018

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DamID: mapping of in vivo protein-genome interactions using tethered DNA adenine methyltransferase

14 July 2018

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Interactions between hairy/enhancer of split-related proteins and the pancreatic transcription factor Ptf1-p48 modulate function of the PTF1 transcriptional complex

14 July 2018

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Hey basic helix-loop-helix transcription factors are repressors of GATA4 and GATA6 and restrict expression of the GATA target gene ANF in fetal hearts

14 July 2018

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Mutations in NOTCH1 cause aortic valve disease

14 July 2018

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Hey1, a mediator of notch signaling, is an androgen receptor corepressor

14 July 2018

1 reference

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Mouse hesr1 and hesr2 genes are redundantly required to mediate Notch signaling in the developing cardiovascular system

14 July 2018

1 reference

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Sequences downstream of the bHLH domain of the Xenopus hairy-related transcription factor-1 act as an extended dimerization domain that contributes to the selection of the partners

14 July 2018

1 reference

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The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation

14 July 2018

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14 July 2018

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Transcriptional repression by the bHLH-Orange factor XHRT1 does not involve the C-terminal YRPW motif

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801253

Phosphorylation and alternative pre-mRNA splicing converge to regulate myocyte enhancer factor 2C activity

14 July 2018

1 reference

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Jun blockade of erythropoiesis: role for repression of GATA-1 by HERP2.

14 July 2018

1 reference

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Pbx marks genes for activation by MyoD indicating a role for a homeodomain protein in establishing myogenic potential

14 July 2018

1 reference

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The Notch target genes Hey1 and Hey2 are required for embryonic vascular development

14 July 2018

1 reference

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Identification of p53 regulators by genome-wide functional analysis

14 July 2018

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Epigenomic profiling using microarrays

14 July 2018

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Hey bHLH factors in cardiovascular development.

14 July 2018

1 reference

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MyoD is functionally linked to the silencing of a muscle-specific regulatory gene prior to skeletal myogenesis

14 July 2018

1 reference

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Promoter-specific regulation of MyoD binding and signal transduction cooperate to pattern gene expression

14 July 2018

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HERP1 is a cell type-specific primary target of Notch

14 July 2018

1 reference

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The Mef2c gene is a direct transcriptional target of myogenic bHLH and MEF2 proteins during skeletal muscle development

14 July 2018

1 reference

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HERP, a novel heterodimer partner of HES/E(spl) in Notch signaling

14 July 2018

1 reference

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HERP, a new primary target of Notch regulated by ligand binding

14 July 2018

1 reference

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Regulation of myogenic terminal differentiation by the hairy-related transcription factor CHF2

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801253

Members of the HRT family of basic helix-loop-helix proteins act as transcriptional repressors downstream of Notch signaling

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801253

Regulation of skeletal myogenesis by association of the MEF2 transcription factor with class II histone deacetylases

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801253

The insulin-like growth factor-phosphatidylinositol 3-kinase-Akt signaling pathway regulates myogenin expression in normal myogenic cells but not in rhabdomyosarcoma-derived RD cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801253

Comparative analysis of the human and mouse Hey1 promoter: Hey genes are new Notch target genes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801253

Identification of in vivo DNA targets of chromatin proteins using tethered dam methyltransferase

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801253

HRT1, HRT2, and HRT3: a new subclass of bHLH transcription factors marking specific cardiac, somitic, and pharyngeal arch segments

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801253

Hey genes: a novel subfamily of hairy- and Enhancer of split related genes specifically expressed during mouse embryogenesis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801253

Expression of myogenin during embryogenesis is controlled by Six/sine oculis homeoproteins through a conserved MEF3 binding site

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801253

Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins

14 July 2018

1 reference

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Myogenin gene disruption results in perinatal lethality because of severe muscle defect

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801253

Muscle deficiency and neonatal death in mice with a targeted mutation in the myogenin gene

14 July 2018

1 reference

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B-cell-specific DNA binding by an E47 homodimer

14 July 2018

1 reference

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Analysis of the myogenin promoter reveals an indirect pathway for positive autoregulation mediated by the muscle-specific enhancer factor MEF-2

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801253

A temporal switch from notch to Wnt signaling in muscle stem cells is necessary for normal adult myogenesis.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801253

Transcriptional repression mediated by repositioning of genes to the nuclear lamina

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801253

The Notch-effector HRT1 gene plays a role in glomerular development and patterning of the Xenopus pronephros anlagen.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801253

HESR1/CHF2 suppresses VEGFR2 transcription independent of binding to E-boxes

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801253

mef2c is activated directly by myogenic basic helix-loop-helix proteins during skeletal muscle development in vivo

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801253

The basic helix-loop-helix genes Hesr1/Hey1 and Hesr2/Hey2 regulate maintenance of neural precursor cells in the brain

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801253

The regulation of Notch signaling controls satellite cell activation and cell fate determination in postnatal myogenesis.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801253

31 October 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/19917614

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Notch-mediated restoration of regenerative potential to aged muscle

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19917614

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M109.046441

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19917614%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19917614%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference