Antitumor and antiangiogenic effect of the dual EGFR and HER-2 tyrosine kinase inhibitor lapatinib in a lung cancer model (Q33575434)

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2 February 2020

title

Antitumor and antiangiogenic effect of the dual EGFR and HER-2 tyrosine kinase inhibitor lapatinib in a lung cancer model (English)

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2 February 2020

main subject

angiogenesis inhibitor

1 reference

1 reference

1

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2 February 2020

Paul A Nguewa

2

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2 February 2020

Miriam Redrado

6

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2 February 2020

María Collantes

8

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2 February 2020

Iván Peñuelas

9

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2 February 2020

Alfonso Calvo

11

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2 February 2020

author name string

Ricardo Parrondo

3

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2 February 2020

Carlos Perez-Stable

4

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2 February 2020

Irene Manrique

5

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2 February 2020

Raul Catena

7

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2 February 2020

Juan Antonio Díaz-González

10

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2 February 2020

language of work or name

English

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publication date

11 May 2010

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2 February 2020

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2 February 2020

volume

10

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2 February 2020

page(s)

188

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https://scigraph.springernature.com/pub.10.1186/1471-2407-10-188

2 February 2020

exact match

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cites work

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Assessment of epidermal growth factor receptor (EGFR, ErbB1) and HER2 (ErbB2) protein expression levels and response to lapatinib (Tykerb, GW572016) in an expanded panel of human normal and tumour cell lines

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Erlotinib, an effective epidermal growth factor receptor tyrosine kinase inhibitor, induces p27KIP1 up-regulation and nuclear translocation in association with cell growth inhibition and G1/S phase arrest in human non-small-cell lung cancer cell lin

21 June 2018

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Cyclin A but not cyclin D1 is essential for c-myc-modulated cell-cycle progression

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Activity of the dual kinase inhibitor lapatinib (GW572016) against HER-2-overexpressing and trastuzumab-treated breast cancer cells

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Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer)

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The epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 selectively potentiates radiation response of human tumors in nude mice, with a marked improvement in therapeutic index.

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12 December 2020

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12 December 2020

Circulating endothelial cells as a marker of endothelial damage in allogeneic hematopoietic stem cell transplantation

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Overexpression of the epidermal growth factor receptor and its ligand transforming growth factor alpha is frequent in resectable non-small cell lung cancer but does not predict tumor progression

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Identifiers

DOI

10.1186/1471-2407-10-188

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20459769%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

2 February 2020

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2 February 2020

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