Putative tumour-suppressor gene DAB2 is frequently down regulated by promoter hypermethylation in nasopharyngeal carcinoma (Q33594982)

28 July 2017

title

Putative tumour-suppressor gene DAB2 is frequently down regulated by promoter hypermethylation in nasopharyngeal carcinoma (English)

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28 July 2017

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Michael W Chan

8

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Kwok Wai Lo

object named as

Kwok W Lo

10

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Anthony Wing-Hung Chan

object named as

Anthony W Chan

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Ka F To

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28 July 2017

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Joanna H Tong

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28 July 2017

3

Shuk L Chau

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28 July 2017

Raymond Wai-Ming Lung

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object named as

Raymond W Lung

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28 July 2017

David C Ng

2

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28 July 2017

Ken K So

4

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28 July 2017

Patrick P Leung

5

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28 July 2017

Tin L Lee

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28 July 2017

language of work or name

English

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publication date

3 June 2010

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28 July 2017

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28 July 2017

volume

10

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28 July 2017

page(s)

253

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C-Fos elimination compensates for disabled-2 requirement in mouse extraembryonic endoderm development

28 July 2017

cites work

1 reference

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Methylation of protocadherin 10, a novel tumor suppressor, is associated with poor prognosis in patients with gastric cancer.

28 July 2018

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Epstein-Barr virus and gastric carcinoma: virus-host interactions leading to carcinoma

28 July 2018

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Nasopharyngeal carcinoma--review of the molecular mechanisms of tumorigenesis

28 July 2018

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The inhibitory effects of Disabled-2 (Dab2) on Wnt signaling are mediated through Axin

28 July 2018

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Activation of DNA methyltransferase 1 by EBV LMP1 Involves c-Jun NH(2)-terminal kinase signaling

28 July 2018

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Frequent loss of Dab2 protein and infrequent promoter hypermethylation in breast cancer.

28 July 2018

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Loss of disabled-2 expression is an early event in esophageal squamous tumorigenesis

28 July 2018

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The role of DOC-2/DAB2 in modulating androgen receptor-mediated cell growth via the nongenomic c-Src-mediated pathway in normal prostatic epithelium and cancer

28 July 2018

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Synergistic induction of DOC-2/DAB2 gene expression in transitional cell carcinoma in the presence of GATA6 and histone deacetylase inhibitor.

28 July 2018

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Disabled-2 (Dab2) mediates transforming growth factor beta (TGFbeta)-stimulated fibronectin synthesis through TGFbeta-activated kinase 1 and activation of the JNK pathway

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891638

Silencing of the retinoid response gene TIG1 by promoter hypermethylation in nasopharyngeal carcinoma

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891638

Focus on nasopharyngeal carcinoma

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891638

RASSF1A is a target tumor suppressor from 3p21.3 in nasopharyngeal carcinoma

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891638

GATA-4 and GATA-5 transcription factor genes and potential downstream antitumor target genes are epigenetically silenced in colorectal and gastric cancer

28 July 2018

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Cell cycle-dependent phosphorylation of Disabled-2 by cdc2

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891638

Regulation of the Wnt signaling pathway by disabled-2 (Dab2)

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891638

Molecular cytogenetic characterization of nasopharyngeal carcinoma cell lines and xenografts by comparative genomic hybridization and spectral karyotyping

28 July 2018

1 reference

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Characterization of a novel negative regulator (DOC-2/DAB2) of c-Src in normal prostatic epithelium and cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891638

Establishment of two immortalized nasopharyngeal epithelial cell lines using SV40 large T and HPV16E6/E7 viral oncogenes.

28 July 2018

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

28 July 2018

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The mechanism of growth-inhibitory effect of DOC-2/DAB2 in prostate cancer. Characterization of a novel GTPase-activating protein associated with N-terminal domain of DOC-2/DAB2

28 July 2018

1 reference

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The inhibitory role of DOC-2/DAB2 in growth factor receptor-mediated signal cascade. DOC-2/DAB2-mediated inhibition of ERK phosphorylation via binding to Grb2

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891638

High frequency of promoter hypermethylation of RASSF1A in nasopharyngeal carcinoma

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891638

Disabled-2 colocalizes with the LDLR in clathrin-coated pits and interacts with AP-2

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891638

Structure, sequence, and promoter analysis of human disabled-2 gene (DAB2).

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891638

High resolution allelotype of microdissected primary nasopharyngeal carcinoma.

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891638

The polo-box-dependent induction of ectopic septal structures by a mammalian polo kinase, plk, in Saccharomyces cerevisiae

28 July 2018

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Disabled-2 inactivation is an early step in ovarian tumorigenicity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891638

Regulation of rat DOC-2 gene during castration-induced rat ventral prostate degeneration and its growth inhibitory function in human prostatic carcinoma cells

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891638

DOC-2, a candidate tumor suppressor gene in human epithelial ovarian cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891638

Cloning of a novel phosphoprotein regulated by colony-stimulating factor 1 shares a domain with the Drosophila disabled gene product.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891638

Disabled-2 (Dab2) is an SH3 domain-binding partner of Grb2

28 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-253

Myosin VI binds to and localises with Dab2, potentially linking receptor-mediated endocytosis and the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-253

Disabled-2 (Dab2) is required for transforming growth factor beta-induced epithelial to mesenchymal transition (EMT)

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-253

DOC-2/hDab2, a candidate tumor suppressor gene involved in the development of gestational trophoblastic diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-253

Epigenetic inactivation of TSLC1 gene in nasopharyngeal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-253

Epigenetic inactivation of the deleted in lung and esophageal cancer 1 gene in nasopharyngeal carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-253

Quantitative Epstein-Barr virus DNA analysis and detection of gene promoter hypermethylation in nasopharyngeal (NP) brushing samples from patients with NP carcinoma

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891638

Down-Regulation of DOC-2 in Colorectal Cancer Points to Its Role as a Tumor Suppressor in This Malignancy

30 October 2018

2 references

https://api.crossref.org/works/10.1186%2F1471-2407-10-253

21 January 2018

12 December 2020

Disabled-2 exerts its tumor suppressor activity by uncoupling c-Fos expression and MAP kinase activation

1 reference

PubMed

12 December 2020

Detection of recurrent chromosomal gains and losses in primary nasopharyngeal carcinoma by comparative genomic hybridisation

1 reference

PubMed

12 December 2020

Decreased DOC-2/DAB2 expression in urothelial carcinoma of the bladder

1 reference

PubMed

12 December 2020

Identifiers

DOI

10.1186/1471-2407-10-253

1 reference

Dimensions Publication ID

28 July 2017

0 references

1 reference

28 July 2017

1 reference