Disabled-2 exerts its tumor suppressor activity by uncoupling c-Fos expression and MAP kinase activation (Q73896123)

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7 November 2019

title

Disabled-2 exerts its tumor suppressor activity by uncoupling c-Fos expression and MAP kinase activation (English)

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7 November 2019

author name string

He J

series ordinal

1

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7 November 2019

Smith ER

series ordinal

2

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7 November 2019

Xu XX

series ordinal

3

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7 November 2019

language of work or name

English

0 references

publication date

18 May 2001

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Journal of Biological Chemistry

7 November 2019

published in

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7 November 2019

volume

276

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7 November 2019

issue

29

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7 November 2019

page(s)

26814-26818

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The pathway to signal achievement

7 November 2019

cites work

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Sequential protein kinase reactions controlling cell growth and differentiation

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Signal transduction--a conserved pathway from the membrane to the nucleus

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

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Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

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Ligand and protein kinase C downmodulate the colony-stimulating factor 1 receptor by independent mechanisms

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Negative Feedback Regulation and Desensitization of Insulin- and Epidermal Growth Factor-stimulated p21ras Activation

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Signal transduction from the extracellular matrix--a role for the focal adhesion protein-tyrosine kinase FAK.

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Aberrant function of the Ras signal transduction pathway in human breast cancer

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Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation

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Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling

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ERK activation induces phosphorylation of Elk-1 at multiple S/T-P motifs to high stoichiometry

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The Elk-1 ETS-domain transcription factor contains a mitogen-activated protein kinase targeting motif.

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The mechanism of phosphorylation-inducible activation of the ETS-domain transcription factor Elk-1.

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Phosphoproteome dynamics reveal novel ERK1/2 MAP kinase substrates with broad spectrum of functions

21 January 2018

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Integration of MAP kinase signal transduction pathways at the serum response element

21 January 2018

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DOC-2, a candidate tumor suppressor gene in human epithelial ovarian cancer

21 January 2018

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Disabled-2 inactivation is an early step in ovarian tumorigenicity

21 January 2018

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Dosage-sensitive modifiers of Drosophila abl tyrosine kinase function: prospero, a regulator of axonal outgrowth, and disabled, a novel tyrosine kinase substrate.

21 January 2018

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Cloning of a novel phosphoprotein regulated by colony-stimulating factor 1 shares a domain with the Drosophila disabled gene product.

21 January 2018

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Disabled-2 (Dab2) is an SH3 domain-binding partner of Grb2

21 January 2018

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Restoration of positioning control following Disabled-2 expression in ovarian and breast tumor cells

21 January 2018

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Regulation of rat DOC-2 gene during castration-induced rat ventral prostate degeneration and its growth inhibitory function in human prostatic carcinoma cells

21 January 2018

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The kinase suppressor of Ras (KSR) modulates growth factor and Ras signaling by uncoupling Elk-1 phosphorylation from MAP kinase activation

21 January 2018

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The calcium/calmodulin-dependent protein phosphatase calcineurin is the major Elk-1 phosphatase

21 January 2018

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Stimulation of Elk1 transcriptional activity by mitogen-activated protein kinases is negatively regulated by protein phosphatase 2B (calcineurin).

21 January 2018

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Gab2, a new pleckstrin homology domain-containing adapter protein, acts to uncouple signaling from ERK kinase to Elk-1

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M101820200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11359772%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

1 reference