Immunostimulatory properties of phosphorothioate CpG DNA containing both 3'-5'- and 2'-5'-internucleotide linkages (Q33601167)

28 July 2017

title

Immunostimulatory properties of phosphorothioate CpG DNA containing both 3'-5'- and 2'-5'-internucleotide linkages (English)

1 reference

28 July 2017

Dong Yu

1

1 reference

28 July 2017

Ekambar R Kandimalla

2

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28 July 2017

Qiuyan Zhao

3

1 reference

28 July 2017

Yanping Cong

4

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28 July 2017

Sudhir Agrawal

5

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28 July 2017

language of work or name

English

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publication date

1 April 2002

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28 July 2017

published in

Nucleic Acids Research

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28 July 2017

volume

30

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28 July 2017

issue

7

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28 July 2017

page(s)

1613-1619

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Antisense and/or immunostimulatory oligonucleotide therapeutics

28 July 2017

cites work

1 reference

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Cutting edge: Role of Toll-like receptor 9 in CpG DNA-induced activation of human cells

21 June 2018

1 reference

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Chemistry and biochemistry of 2',5'-oligoadenylate-based antisense strategy

21 June 2018

1 reference

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Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition

21 June 2018

1 reference

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Non-specific antiviral activity of antisense molecules targeted to the E1 region of human papillomavirus

21 June 2018

1 reference

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Human peripheral blood cells differentially recognize and respond to two distinct CPG motifs

21 June 2018

1 reference

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DNA-PKcs is required for activation of innate immunity by immunostimulatory DNA.

21 June 2018

1 reference

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A Toll-like receptor recognizes bacterial DNA

21 June 2018

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Conjugation of immunostimulatory DNA to the short ragweed allergen amb a 1 enhances its immunogenicity and reduces its allergenicity

21 June 2018

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Antisense therapeutics: is it as simple as complementary base recognition?

21 June 2018

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Delineation of a CpG phosphorothioate oligodeoxynucleotide for activating primate immune responses in vitro and in vivo

21 June 2018

1 reference

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Site of chemical modifications in CpG containing phosphorothioate oligodeoxynucleotide modulates its immunostimulatory activity

21 June 2018

1 reference

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Effects of phosphorothioate oligodeoxyribonucleotide and oligoribonucleotides on human complement and coagulation

21 June 2018

1 reference

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CpG oligodeoxynucleotides trigger protective and curative Th1 responses in lethal murine leishmaniasis.

21 June 2018

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2',5'-linked oligo-3'-deoxyribonucleoside phosphorothioate chimeras: thermal stability and antisense inhibition of gene expression

21 June 2018

1 reference

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Mixed backbone antisense oligonucleotides: design, biochemical and biological properties of oligonucleotides containing 2'-5'-ribo- and 3'-5'-deoxyribonucleotide segments

21 June 2018

1 reference

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CpG motifs in bacterial DNA trigger direct B-cell activation

21 June 2018

1 reference

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Oligoribonucleotides containing 2′,5′-phosphodiester linkages exhibit binding selectivity for 3′,5′-RNA over 3′,5′-ssDNA

21 June 2018

1 reference

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(2'-5')-Oligo-3'-deoxynucleotides: selective binding to single-stranded RNA but not DNA.

21 June 2018

1 reference

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NK- and CD8(+) T cell-mediated eradication of established tumors by peritumoral injection of CpG-containing oligodeoxynucleotides.

21 June 2018

1 reference

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Divergent therapeutic and immunologic effects of oligodeoxynucleotides with distinct CpG motifs.

30 October 2018

1 reference

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Immunization of woodchucks (Marmota monax) with hepatitis delta virus DNA vaccine

30 October 2018

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Antimetastatic effect of CpG DNA mediated by type I IFN.

30 October 2018

1 reference

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NMR structure of a 2',5' RNA favors A type duplex with compact C2'endo nucleotide repeat

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=101845

Effect of chemical modifications of cytosine and guanine in a CpG-motif of oligonucleotides: structure-immunostimulatory activity relationships

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=101845

Vaccination with DNA containing tat coding sequences and unmethylated CpG motifs protects cynomolgus monkeys upon infection with simian/human immunodeficiency virus (SHIV89.6P).

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=101845

Regulation of murine airway eosinophilia and Th2 cells by antigen-conjugated CpG oligodeoxynucleotides as a novel antigen-specific immunomodulator.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=101845

CpG DNA overcomes hyporesponsiveness to hepatitis B vaccine in orangutans

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=101845

Synthetic oligonucleotides with particular base sequences from the cDNA encoding proteins of Mycobacterium bovis BCG induce interferons and activate natural killer cells

30 October 2018

1 reference

12 December 2020

Effect of different chemically modified oligodeoxynucleotides on immune stimulation

1 reference

12 December 2020

Pattern and kinetics of cytokine production following administration of phosphorothioate oligonucleotides in mice

1 reference

12 December 2020

Immunostimulatory activity of CpG containing phosphorothioate oligodeoxynucleotide is modulated by modification of a single deoxynucleoside

1 reference

12 December 2020

Modulation of immunostimulatory activity of CpG oligonucleotides by site-specific deletion of nucleobases

1 reference

12 December 2020

Immunostimulatory activity of CpG oligonucleotides containing non-ionic methylphosphonate linkages

1 reference

12 December 2020

Stereochemistry of 2',5' nucleic acids and their constituents

1 reference

12 December 2020

Immune stimulation by an antisense oligomer complementary to the rev gene of HIV-1

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/30.7.1613

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28 July 2017

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28 July 2017

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