Critical role for transcriptional repressor Snail2 in transformation by oncogenic RAS in colorectal carcinoma cells (Q33609650)

28 July 2017

Critical role for transcriptional repressor Snail2 in transformation by oncogenic RAS in colorectal carcinoma cells (English)

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28 July 2017

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7

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28 July 2017

1

Y Wang

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28 July 2017

V N Ngo

2

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28 July 2017

M Marani

3

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28 July 2017

Y Yang

4

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28 July 2017

G Wright

5

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28 July 2017

L M Staudt

6

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28 July 2017

language of work or name

English

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publication date

21 June 2010

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28 July 2017

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29

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28 July 2017

33

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28 July 2017

4658-4670

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https://scigraph.springernature.com/pub.10.1038/onc.2010.218

28 July 2017

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cites work

Role of the epithelial-mesenchymal transition regulator Slug in primary human cancers

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https://api.crossref.org/works/10.1038%2FONC.2010.218

Regulation of Snail transcription during epithelial to mesenchymal transition of tumor cells

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shRNA libraries and their use in cancer genetics

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Function of the zinc-finger transcription factor SNAI2 in cancer and development

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.218

Snail and slug play distinct roles during breast carcinoma progression.

31 March 2020

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Autoregulation of E-cadherin expression by cadherin-cadherin interactions: the roles of beta-catenin signaling, Slug, and MAPK

31 March 2020

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31 March 2020

SnapShot: Ras Signaling

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https://api.crossref.org/works/10.1038%2FONC.2010.218

Epidermal Ras blockade demonstrates spatially localized Ras promotion of proliferation and inhibition of differentiation

31 March 2020

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Replacement of normal with mutant alleles in the genome of normal human cells unveils mutation-specific drug responses

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Targeting RAS signalling pathways in cancer therapy

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Use of RNA interference libraries to investigate oncogenic signalling in mammalian cells

31 March 2020

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The melanocyte differentiation program predisposes to metastasis after neoplastic transformation

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Integrating genetic approaches into the discovery of anticancer drugs

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Snail/slug family of repressors: slowly going into the fast lane of development and cancer

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Molecular requirements for epithelial-mesenchymal transition during tumor progression

31 March 2020

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Slug, a highly conserved zinc finger transcriptional repressor, protects hematopoietic progenitor cells from radiation-induced apoptosis in vivo.

31 March 2020

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Utilizing RNA interference to enhance cancer drug discovery

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A molecular signature for Epithelial to Mesenchymal transition in a human colon cancer cell system is revealed by large-scale microarray analysis.

31 March 2020

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The concept of synthetic lethality in the context of anticancer therapy

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Aberrant expression of the transcription factors snail and slug alters the response to genotoxic stress

31 March 2020

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Ras oncogenes: split personalities

31 March 2020

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Snail and slug mediate radioresistance and chemoresistance by antagonizing p53-mediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells

31 March 2020

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Epithelial-mesenchymal transition in development and cancer: role of phosphatidylinositol 3' kinase/AKT pathways

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Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells

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A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene

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A loss-of-function RNA interference screen for molecular targets in cancer

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The snail superfamily of zinc-finger transcription factors

31 March 2020

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TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells

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Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?

31 March 2020

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Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.218

The radioresistance biological function of the SCF/kit signaling pathway is mediated by the zinc-finger transcription factor Slug

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.218

SLUG in cancer development.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.218

Requirement of the Akt/beta-catenin pathway for uterine carcinosarcoma genesis, modulating E-cadherin expression through the transactivation of slug

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.218

E-cadherin is regulated by the transcriptional repressor SLUG during Ras-mediated transformation of intestinal epithelial cells

31 March 2020

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Synthetic lethal interaction between oncogenic KRAS dependency and STK33 suppression in human cancer cells

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IRF4 addiction in multiple myeloma

31 March 2020

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Slug expression is an independent prognostic parameter for poor survival in colorectal carcinoma patients

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.218

Altered growth of human colon cancer cell lines disrupted at activated Ki-ras

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.218

A gene expression signature associated with "K-Ras addiction" reveals regulators of EMT and tumor cell survival

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.218

Complex networks orchestrate epithelial-mesenchymal transitions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.218

Epithelial to mesenchymal transition is a determinant of sensitivity of non-small-cell lung carcinoma cell lines and xenografts to epidermal growth factor receptor inhibition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.218

Slug (SNAI2) down-regulation by RNA interference facilitates apoptosis and inhibits invasive growth in neuroblastoma preclinical models

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.218

p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.218

Raf 1 represses expression of the tight junction protein occludin via activation of the zinc-finger transcription factor slug

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.218

Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.218

Short interfering RNA directed against the SLUG gene increases cell death induction in human melanoma cell lines exposed to cisplatin and fotemustine.

31 March 2020

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12 December 2020

Genetics of natural populations; recombination and variability in populations of Drosophila pseudoobscura.

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12 December 2020

The SLUG zinc-finger protein represses E-cadherin in breast cancer

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12 December 2020

The Slug gene is not essential for mesoderm or neural crest development in mice.

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12 December 2020

Comparative genomics on SNAI1, SNAI2, and SNAI3 orthologs.

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12 December 2020

Identifiers

DOI

10.1038/ONC.2010.218

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Dimensions Publication ID

28 July 2017

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