Transcriptional repression of Kruppel like factor-2 by the adaptor protein p66shc. (Q33613299)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19696221%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

title

Transcriptional repression of Kruppel like factor-2 by the adaptor protein p66shc (English)

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5 February 2020

6

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5 February 2020

author name string

Ajay Kumar

1

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5 February 2020

Timothy A Hoffman

2

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5 February 2020

Jeremy Dericco

3

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5 February 2020

Asma Naqvi

4

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5 February 2020

Mukesh K Jain

5

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5 February 2020

language of work or name

English

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publication date

20 August 2009

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5 February 2020

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5 February 2020

volume

23

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5 February 2020

issue

12

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5 February 2020

page(s)

4344-4352

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Nuclear respiratory factor 1 controls myocyte enhancer factor 2A transcription to provide a mechanism for coordinate expression of respiratory chain subunits

5 February 2020

cites work

1 reference

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Myocyte enhancer factor 2A is transcriptionally autoregulated

21 June 2018

1 reference

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Sos-mediated activation of rac1 by p66shc

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812051

Activity-dependent regulation of MEF2 transcription factors suppresses excitatory synapse number

21 June 2018

1 reference

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Integration of flow-dependent endothelial phenotypes by Kruppel-like factor 2

21 June 2018

1 reference

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P66shc regulates endothelial NO production and endothelium-dependent vasorelaxation: implications for age-associated vascular dysfunction

21 June 2018

1 reference

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Expression of p66(Shc) protein correlates with proliferation of human prostate cancer cells.

21 June 2018

1 reference

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VEGF-integrin interplay controls tumor growth and vascularization.

21 June 2018

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Kruppel-like factor 2 (KLF2) regulates endothelial thrombotic function

21 June 2018

1 reference

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21 June 2018

Signaling to NF-kappaB

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KLF2 Is a novel transcriptional regulator of endothelial proinflammatory activation

21 June 2018

1 reference

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p66SHC promotes apoptosis and antagonizes mitogenic signaling in T cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812051

Cdk5-Mediated Inhibition of the Protective Effects of Transcription Factor MEF2 in Neurotoxicity-Induced Apoptosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812051

Deletion of the p66Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812051

The Krüppel-like factor KLF2 inhibits peroxisome proliferator-activated receptor-gamma expression and adipogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812051

MEF2: a calcium-dependent regulator of cell division, differentiation and death

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812051

Evolution of Shc functions from nematode to human

21 June 2018

1 reference

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Recent advances towards understanding redox mechanisms in the activation of nuclear factor kappaB.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812051

Big mitogen-activated kinase regulates multiple members of the MEF2 protein family

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812051

Elevated levels of p66 Shc are found in breast cancer cell lines and primary tumors with high metastatic potential

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812051

The p66shc adaptor protein controls oxidative stress response and life span in mammals

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812051

Apoptosis of T cells mediated by Ca2+-induced release of the transcription factor MEF2

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812051

Lung Kruppel-like factor, a zinc finger transcription factor, is essential for normal lung development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812051

Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812051

Requirement of the MADS-box transcription factor MEF2C for vascular development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812051

BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2C

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812051

The LKLF transcription factor is required for normal tunica media formation and blood vessel stabilization during murine embryogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812051

Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812051

Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor-MAP kinase-fos signalling pathway.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812051

Isolation, genomic structure, and expression of human erythroid Krüppel-like factor (EKLF)

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812051

Not all Shc's roads lead to Ras

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812051

Lethal beta-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812051

Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812051

Isolation of a gene encoding a functional zinc finger protein homologous to erythroid Krüppel-like factor: identification of a new multigene family

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812051

Kruppel-like factor 2 as a novel mediator of statin effects in endothelial cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812051

Tumor necrosis factor alpha-mediated reduction of KLF2 is due to inhibition of MEF2 by NF-kappaB and histone deacetylases

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812051

Inhibition of vascular permeability factor/vascular endothelial growth factor-mediated angiogenesis by the Kruppel-like factor KLF2.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812051

The life span determinant p66Shc localizes to mitochondria where it associates with mitochondrial heat shock protein 70 and regulates trans-membrane potential.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812051

A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812051

Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812051

Transcription factors as targets for oxidative signalling during lymphocyte activation.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812051

LKLF: A transcriptional regulator of single-positive T cell quiescence and survival

30 October 2018

1 reference

12 December 2020

Electron Transfer between Cytochrome c and p66Shc Generates Reactive Oxygen Species that Trigger Mitochondrial Apoptosis

1 reference

12 December 2020

KLF2 provokes a gene expression pattern that establishes functional quiescent differentiation of the endothelium

1 reference

12 December 2020

Deletion of p66Shc longevity gene protects against experimental diabetic glomerulopathy by preventing diabetes-induced oxidative stress

1 reference

12 December 2020

p66SHC promotes T cell apoptosis by inducing mitochondrial dysfunction and impaired Ca2+ homeostasis

1 reference

12 December 2020

Identifiers

DOI

10.1096/FJ.09-138743

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19696221%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19696221%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference