The algal hepatoxoxin okadaic acid is a substrate for human cytochromes CYP3A4 and CYP3A5. (Q33620648)

28 July 2017

title

The algal hepatoxoxin okadaic acid is a substrate for human cytochromes CYP3A4 and CYP3A5. (English)

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28 July 2017

Fujiang Guo

1

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28 July 2017

Tianying An

series ordinal

2

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28 July 2017

Kathleen S Rein

series ordinal

3

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28 July 2017

language of work or name

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20 August 2009

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28 July 2017

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28 July 2017

volume

55

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28 July 2017

issue

2-3

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28 July 2017

page(s)

325-332

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The cytotoxicity and genotoxicity of okadaic acid are cell-line dependent

28 July 2017

cites work

1 reference

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Characterization of fatty acid esters of okadaic acid and related toxins in blue mussels (Mytilus edulis) from Norway

21 June 2018

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Structure of protein phosphatase 2A core enzyme bound to tumor-inducing toxins

21 June 2018

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Microcystin-LR and okadaic acid-induced cellular effects: a dualistic response.

21 June 2018

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Aneugenic potential of okadaic acid revealed by the micronucleus assay combined with the FISH technique in CHO-K1 cells.

21 June 2018

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Okadaic acid: the archetypal serine/threonine protein phosphatase inhibitor

21 June 2018

1 reference

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Okadaic acid treatment induces DNA adduct formation in BHK21 C13 fibroblasts and HESV keratinocytes

21 June 2018

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Tumor promotion by inhibitors of protein phosphatases 1 and 2A: the okadaic acid class of compounds

21 June 2018

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Okadaic acid, a protein phosphatase inhibitor, induces sister-chromatid exchanges depending on the presence of bromodeoxyuridine

21 June 2018

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Mass spectrometric analysis of the marine lipophilic biotoxins pectenotoxin-2 and okadaic acid by four different types of mass spectrometers

21 June 2018

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Overview of key phytoplankton toxins and their recent occurrence in the North and Baltic Seas.

30 October 2018

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Testosterone 1 beta-hydroxylation by human cytochrome P450 3A4.

30 October 2018

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Marine toxin okadaic acid induces aneuploidy in CHO-K1 cells in presence of rat liver postmitochondrial fraction, revealed by cytokinesis-block micronucleus assay coupled to FISH.

30 October 2018

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Enantioselectivity of inhibition of cytochrome P450 3A4 (CYP3A4) by ketoconazole: Testosterone and methadone as substrates

30 October 2018

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Contribution of individual cytochrome P450 isozymes to the O-demethylation of the psychotropic beta-carboline alkaloids harmaline and harmine.

30 October 2018

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Micronucleus induction in mussels exposed to okadaic acid.

30 October 2018

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Regioselective metabolism of taxoids by human CYP3A4 and 2C8: structure-activity relationship

30 October 2018

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Investigation of the distribution and excretion of okadaic acid in mice using immunostaining method

30 October 2018

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Esterification of DSP toxins by Portuguese bivalves from the Northwest coast determined by LC-MS--a widespread phenomenon

30 October 2018

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A protein phosphatase 2A inhibition assay for a fast and sensitive assessment of okadaic acid contamination in mussels.

30 October 2018

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Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P-450IIE1

30 October 2018

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12 December 2020

Effects of the tumour promoter okadaic acid on intracellular protein phosphorylation and metabolism

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12 December 2020

Highly sensitive assay of okadaic acid using protein phosphatase and paranitrophenyl phosphate

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12 December 2020

Fast determination of low-level cytochrome P-450 1A1 activity by high-performance liquid chromatography with fluorescence or visible absorbance detection

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12 December 2020

Different contributions of cytochrome P450 2C19 and 3A4 in the oxidation of omeprazole by human liver microsomes: effects of contents of these two forms in individual human samples

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12 December 2020

Variations in the distribution of okadaic acid in organs and biological fluids of mice related to diarrhoeic syndrome

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12 December 2020

Esters of okadaic acid and dinophysistoxin-2 in Portuguese bivalves related to human poisonings

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12 December 2020

Identification and characterization of DTX-5c and 7-hydroxymethyl-2-methylene-octa-4,7-dienyl okadaate from Prorocentrum belizeanum cultures by LC-MS

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12 December 2020

Detection of new 7-O-acyl derivatives of diarrhetic shellfish poisoning toxins by liquid chromatography-mass spectrometry

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12 December 2020

10.1016/J.TOXICON.2009.08.007

Identifiers

DOI

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28 July 2017

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28 July 2017

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