Mapping pathological phenotypes in a mouse model of CDKL5 disorder (Q33623490)

28 July 2017

title

Mapping pathological phenotypes in a mouse model of CDKL5 disorder (English)

1 reference

CDKL5 deficiency disorder

28 July 2017

main subject

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Dominika Farley

10

0 references

Yang Zhan

Yang Zhan

2

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Enrico Castroflorio

Enrico Castroflorio

4

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Alexei L. Vyssotski

Alexei L Vyssotski

9

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Elisabetta Ciani

Elisabetta Ciani

11

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Maurizio Giustetto

Maurizio Giustetto

13

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Tommaso Pizzorusso

Tommaso Pizzorusso

12

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author name string

Elena Amendola

1

1 reference

28 July 2017

Camilla Mattucci

3

1 reference

28 July 2017

Eleonora Calcagno

5

1 reference

28 July 2017

Claudia Fuchs

6

1 reference

28 July 2017

Giuseppina Lonetti

7

1 reference

28 July 2017

Davide Silingardi

8

1 reference

28 July 2017

Cornelius T Gross

14

1 reference

28 July 2017

language of work or name

English

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publication date

16 May 2014

1 reference

28 July 2017

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28 July 2017

volume

9

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28 July 2017

issue

5

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28 July 2017

page(s)

e91613

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Creative Commons Attribution 4.0 International

28 July 2017

copyright license

start time

16 May 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4023934/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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1 reference

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The CDKL5 disorder is an independent clinical entity associated with early-onset encephalopathy

21 June 2018

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MeCP2 mutation results in compartment-specific reductions in dendritic branching and spine density in layer 5 motor cortical neurons of YFP-H mice

21 June 2018

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21 June 2018

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CDKL5, a protein associated with rett syndrome, regulates neuronal morphogenesis via Rac1 signaling

21 June 2018

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CDKL5 influences RNA splicing activity by its association to the nuclear speckle molecular machinery

21 June 2018

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21 June 2018

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Key clinical features to identify girls with CDKL5 mutations

21 June 2018

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CDKL5 expression is modulated during neuronal development and its subcellular distribution is tightly regulated by the C-terminal tail

21 June 2018

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RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation

21 June 2018

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21 June 2018

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Brain-specific phosphorylation of MeCP2 regulates activity-dependent Bdnf transcription, dendritic growth, and spine maturation

21 June 2018

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21 June 2018

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Mecp2 deficiency is associated with learning and cognitive deficits and altered gene activity in the hippocampal region of mice

21 June 2018

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21 June 2018

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CDKL5 belongs to the same molecular pathway of MeCP2 and it is responsible for the early-onset seizure variant of Rett syndrome

21 June 2018

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A focused and efficient genetic screening strategy in the mouse: identification of mutations that disrupt cortical development

21 June 2018

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S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway

21 June 2018

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21 June 2018

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21 June 2018

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21 January 2018

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21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/24838000

12 December 2020

inferred from PubMed ID database lookup

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Identifiers

DOI

10.1371/JOURNAL.PONE.0091613

1 reference

28 July 2017

0 references

1 reference

28 July 2017

1 reference