Peptides and Pseudopeptides as SIRT6 Deacetylation Inhibitors (Q33630602)

24900419

28 July 2017

title

Peptides and Pseudopeptides as SIRT6 Deacetylation Inhibitors (English)

1 reference

28 July 2017

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900419%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Tuomo Laitinen

series ordinal

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900419%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Antti Poso

series ordinal

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900419%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Maija K Lahtela-Kakkonen

series ordinal

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900419%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

2

Minna Rahnasto-Rilla

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900419%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

3

Päivi H Kiviranta

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900419%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

4

Tero Huhtiniemi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900419%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

7

Elina Jarho

1 reference

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7 June 2020

language of work or name

1 reference

23 October 2012

1 reference

24900419

ACS Medicinal Chemistry Letters

28 July 2017

published in

1 reference

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7 June 2020

volume

3

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7 June 2020

issue

12

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900419%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

page(s)

969-974

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900419%20AND%20SRC:MED&resulttype=core&format=json

Are sirtuins viable targets for improving healthspan and lifespan?

7 June 2020

cites work

1 reference

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The sirtuin SIRT6 regulates lifespan in male mice

21 June 2018

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Sirtuin 6 protects cardiomyocytes from hypertrophy in vitro via inhibition of NF-κB-dependent transcriptional activity

21 June 2018

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Repairing split ends: SIRT6, mono-ADP ribosylation and DNA repair.

21 June 2018

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Structure-based development of novel sirtuin inhibitors

21 June 2018

1 reference

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Synthesis and characterization of SIRT6 protein coated magnetic beads: identification of a novel inhibitor of SIRT6 deacetylase from medicinal plant extracts

21 June 2018

1 reference

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SIRT6 promotes DNA repair under stress by activating PARP1

21 June 2018

1 reference

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Medicinal chemistry of sirtuin inhibitors

21 June 2018

1 reference

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Structure and biochemical functions of SIRT6.

21 June 2018

1 reference

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SIRT6 Deficiency Results in Severe Hypoglycemia by Enhancing Both Basal and Insulin-stimulated Glucose Uptake in Mice

21 June 2018

1 reference

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Human SIRT6 promotes DNA end resection through CtIP deacetylation

21 June 2018

1 reference

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SIRT6 protects against pathological damage caused by diet-induced obesity

21 June 2018

1 reference

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Catastrophic NAD+ depletion in activated T lymphocytes through Nampt inhibition reduces demyelination and disability in EAE.

21 June 2018

1 reference

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Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6.

21 June 2018

1 reference

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Crystal structures of human SIRT3 displaying substrate-induced conformational changes

21 June 2018

1 reference

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SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin

21 June 2018

1 reference

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Genomic instability and aging-like phenotype in the absence of mammalian SIRT6

21 June 2018

1 reference

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VMD: visual molecular dynamics

21 June 2018

1 reference

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N(epsilon)-Modified lysine containing inhibitors for SIRT1 and SIRT2.

21 June 2018

1 reference

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The sirtuin SIRT6 deacetylates H3 K56Ac in vivo to promote genomic stability

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4025866

Substituting N(epsilon)-thioacetyl-lysine for N(epsilon)-acetyl-lysine in peptide substrates as a general approach to inhibiting human NAD(+)-dependent protein deacetylases

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4025866

N(epsilon)-thioacetyl-lysine-containing tri-, tetra-, and pentapeptides as SIRT1 and SIRT2 inhibitors.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4025866

Investigating the ADP-ribosyltransferase activity of sirtuins with NAD analogues and 32P-NAD.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4025866

Mechanism-based inhibition of Sir2 deacetylases by thioacetyl-lysine peptide

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4025866

The Structural Basis of Sirtuin Substrate Affinity†,‡

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4025866

Structure-based design of pseudopeptidic inhibitors for SIRT1 and SIRT2

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24900419

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/ML300139N

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900419%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900419%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

24900419

1 reference