Altered agonist sensitivity of a mutant v2 receptor suggests a novel therapeutic strategy for nephrogenic diabetes insipidus. (Q33632079)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24628417%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

title

Altered agonist sensitivity of a mutant v2 receptor suggests a novel therapeutic strategy for nephrogenic diabetes insipidus (English)

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10 March 2020

2

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10 March 2020

author name string

László Sándor Erdélyi

1

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10 March 2020

Attila Patócs

3

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10 March 2020

Miklós Tóth

4

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10 March 2020

Péter Várnai

5

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10 March 2020

László Hunyady

6

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10 March 2020

publication date

14 March 2014

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10 March 2020

published in

Molecular Endocrinology

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10 March 2020

volume

28

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10 March 2020

page(s)

634-643

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10 March 2020

issue

5

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Nephrogenic diabetes insipidus: essential insights into the molecular background and potential therapies for treatment.

10 March 2020

cites work

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Intracellular activation of vasopressin V2 receptor mutants in nephrogenic diabetes insipidus by nonpeptide agonists

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Identification, characterization and rescue of a novel vasopressin-2 receptor mutation causing nephrogenic diabetes insipidus

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21 June 2018

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Functional rescue of vasopressin V2 receptor mutants in MDCK cells by pharmacochaperones: relevance to therapy of nephrogenic diabetes insipidus

21 June 2018

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Cell biological aspects of the vasopressin type-2 receptor and aquaporin 2 water channel in nephrogenic diabetes insipidus

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21 June 2018

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21 June 2018

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21 June 2018

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Functional studies of twelve mutant V2 vasopressin receptors related to nephrogenic diabetes insipidus: molecular basis of a mild clinical phenotype.

30 October 2018

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[1-deaminopenicillamine,4-valine]-8-D-arginine-vasopressin, a highly potent inhibitor of the vasopressor response to arginine-vasopressin

30 October 2018

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Report of 33 novel AVPR2 mutations and analysis of 117 families with X-linked nephrogenic diabetes insipidus

30 October 2018

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12 December 2020

The conserved seven-transmembrane sequence NP(X)2,3Y of the G-protein-coupled receptor superfamily regulates multiple properties of the beta 2-adrenergic receptor

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12 December 2020

Nephrogenic diabetes insipidus. A V2 vasopressin receptor unable to stimulate adenylyl cyclase

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12 December 2020

1,6-Aminosuberic acid analogs of lysine- and arginine-vasopressin and -vasotocin. Synthesis and biological properties

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12 December 2020

[Treatment of diabetes insipidus with synthetic vasopressin derivatives (effect of 1-deamino-8-D-arginine vasopressin and 1-deamino-valine-8-D-arginine vasopressin)]

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12 December 2020

A Conserved NPLFY Sequence Contributes to Agonist Binding and Signal Transduction but Is Not an Internalization Signal for the Type 1 Angiotensin II Receptor

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12 December 2020

Identifiers

DOI

10.1210/ME.2013-1424

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24628417%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24628417%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24628417%20AND%20SRC:MED&resulttype=core&format=json