Genetic polymorphisms in MDR1, CYP3A4 and CYP3A5 genes in a Ghanaian population: a plausible explanation for altered metabolism of ivermectin in humans? (Q33632608)

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English	Genetic polymorphisms in MDR1, CYP3A4 and CYP3A5 genes in a Ghanaian population: a plausible explanation for altered metabolism of ivermectin in humans?	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

academic journal article

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Genetic polymorphisms in MDR1, CYP3A4 and CYP3A5 genes in a Ghanaian population: a plausible explanation for altered metabolism of ivermectin in humans? (English)

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

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author name string

William Kudzi

1

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Alexander N O Dodoo

2

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Jeremy J Mills

3

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Kudzi, William

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Dodoo, Alexander NO

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Mills, Jeremy J

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Kudzi, W.

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Dodoo, A.N.

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Mills, J.J.

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publication date

14 July 2010

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

2010

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BMC Medical Genetics

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

11

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

111

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

http://ugspace.ug.edu.gh/handle/123456789/5619

0 references

CYP3A4 and CYP3A5 genotyping by Pyrosequencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161347

21 June 2018

Unmasking the dynamic interplay between efflux transporters and metabolic enzymes.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161347

21 June 2018

An investigation of persistent microfilaridermias despite multiple treatments with ivermectin, in two onchocerciasis-endemic foci in Ghana

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161347

21 June 2018

Polymorphisms in human MDR1 (P-glycoprotein): recent advances and clinical relevance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161347

21 June 2018

The Current State of the Onchocerciasis Control Programme in West Africa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161347

21 June 2018

Genetic polymorphisms of CYP2C9 and CYP2C19 in the Beninese and Belgian populations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161347

21 June 2018

P-glycoprotein in helminths: function and perspectives for anthelmintic treatment and reversal of resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161347

21 June 2018

Pharmacogenetics of MDR1 and its impact on the pharmacokinetics and pharmacodynamics of drugs

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161347

21 June 2018

Association of the multidrug resistance-1 gene single-nucleotide polymorphisms with the tacrolimus dose requirements in renal transplant recipients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161347

21 June 2018

Final report of the Conference on the eradicability of Onchocerciasis

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21 June 2018

Ethnic differences in the frequency of prostate cancer susceptibility alleles at SRD5A2 and CYP3A4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161347

21 June 2018

Genetic contribution to variable human CYP3A-mediated metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161347

21 June 2018

Genetic polymorphisms of the human MDR1 drug transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161347

21 June 2018

Role of transport proteins in drug absorption, distribution and excretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161347

21 June 2018

The gut as a barrier to drug absorption: combined role of cytochrome P450 3A and P-glycoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161347

21 June 2018

CYP3A4 promoter variant in Saudi, Ghanaian and Scottish Caucasian populations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161347

21 June 2018

Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161347

21 June 2018

Association of CYP3A4 genotype with treatment-related leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161347

21 June 2018

HIV-1 protease inhibitors are substrates for the MDR1 multidrug transporter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161347

21 June 2018

Characterization of interintestinal and intraintestinal variations in human CYP3A-dependent metabolism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161347

21 June 2018

P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature.

2 references

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21 June 2018

https://api.crossref.org/works/10.1186%2F1471-2350-11-111

21 January 2018

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161347

21 June 2018

Stage-specific distribution of P-glycoprotein in first-trimester and full-term human placenta.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161347

21 June 2018

Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161347

21 June 2018

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161347

21 June 2018

Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-11-111

21 January 2018

Interindividual variability and tissue-specificity in the expression of cytochrome P450 3A mRNA.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-11-111

21 January 2018

Identification of cytochrome P4503A4 as the major enzyme responsible for the metabolism of ivermectin by human liver microsomes.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-11-111

21 January 2018

Modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-11-111

21 January 2018

Identification and functional characterization of eight CYP3A4 protein variants

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-11-111

21 January 2018

Association between the CYP3A5 genotype and blood pressure

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-11-111

21 January 2018

Thirty-month follow-up of sub-optimal responders to multiple treatments with ivermectin, in two onchocerciasis-endemic foci in Ghana

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-11-111

21 January 2018

Genomic organization and effects of ivermectin selection on Onchocerca volvulus P-glycoprotein.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-11-111

21 January 2018

Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-11-111

21 January 2018

MDR1 pharmacogenetics: frequency of the C3435T mutation in exon 26 is significantly influenced by ethnicity

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-11-111

21 January 2018

Genetic polymorphisms in MDR1 and CYP3A4 genes in Asians and the influence of MDR1 haplotypes on cyclosporin disposition in heart transplant recipients

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-11-111

21 January 2018

Role of human MDR1 gene polymorphism in bioavailability and interaction of digoxin, a substrate of P-glycoprotein.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-11-111

21 January 2018

Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-11-111

21 January 2018

CYP3A4 promoter variant is associated with prostate cancer risk in men with benign prostate hyperplasia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161347

30 October 2018

The genetic determinants of the CYP3A5 polymorphism

1 reference

https://pubmed.ncbi.nlm.nih.gov/20630055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/20630055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CYP3A5*3 and *6 single nucleotide polymorphisms in three distinct Asian populations

1 reference

https://pubmed.ncbi.nlm.nih.gov/20630055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacogenetic screening for polymorphisms in drug-metabolizing enzymes and drug transporters in a Dutch population

1 reference

https://pubmed.ncbi.nlm.nih.gov/20630055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Significant genetic linkage of MDR1 polymorphisms at positions 3435 and 2677: functional relevance to pharmacokinetics of digoxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20630055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CYP3A5 variant allele frequencies in Dutch Caucasians

1 reference

https://pubmed.ncbi.nlm.nih.gov/20630055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1471-2350-11-111

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Dimensions Publication ID

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

ResearchGate publication ID

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University of Ghana Digital Collections (UGSpace) ID

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