Palmitoylation regulates 17β-estradiol-induced estrogen receptor-α degradation and transcriptional activity (Q33636588)

28 July 2017

title

Palmitoylation regulates 17β-estradiol-induced estrogen receptor-α degradation and transcriptional activity (English)

1 reference

28 July 2017

1 reference

Piergiorgio La Rosa

1

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28 July 2017

Valeria Pesiri

2

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28 July 2017

Guy Leclercq

3

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28 July 2017

Maria Marino

4

1 reference

28 July 2017

Filippo Acconcia

5

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28 July 2017

publication date

22 March 2012

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28 July 2017

published in

Molecular Endocrinology

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28 July 2017

volume

26

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28 July 2017

issue

5

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28 July 2017

page(s)

762-774

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DHHC-7 and -21 are palmitoylacyltransferases for sex steroid receptors

28 July 2017

cites work

1 reference

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Role of ERbeta palmitoylation in the inhibition of human colon cancer cell proliferation.

21 June 2018

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An inherent role of integrin-linked kinase-estrogen receptor alpha interaction in cell migration.

21 June 2018

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Ciz1, a Novel DNA-binding coactivator of the estrogen receptor alpha, confers hypersensitivity to estrogen action

21 June 2018

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Palmitoylation of ligands, receptors, and intracellular signaling molecules

21 June 2018

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Estrogen receptor-alpha phosphorylated at Ser118 is present at the promoters of estrogen-regulated genes and is not altered due to HER-2 overexpression

21 June 2018

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Structure-function relationship of estrogen receptor alpha and beta: impact on human health

21 June 2018

1 reference

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S-palmitoylation modulates estrogen receptor alpha localization and functions.

21 June 2018

1 reference

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Glycogen synthase kinase-3 interacts with and phosphorylates estrogen receptor alpha and is involved in the regulation of receptor activity

21 June 2018

1 reference

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Differential regulation of estrogen-inducible proteolysis and transcription by the estrogen receptor alpha N terminus

21 June 2018

1 reference

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Role of the proteasome in the regulation of estrogen receptor alpha turnover and function in MCF-7 breast carcinoma cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417099

Ligand-independent and agonist-mediated degradation of estrogen receptor-alpha in breast carcinoma cells: evidence for distinct degradative pathways

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417099

Palmitoylation-dependent estrogen receptor alpha membrane localization: regulation by 17beta-estradiol

21 June 2018

1 reference

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Protein kinase A activation of estrogen receptor alpha transcription does not require proteasome activity and protects the receptor from ligand-mediated degradation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417099

Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417099

Characterization of human palmitoyl-acyl transferase activity using peptides that mimic distinct palmitoylation motifs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417099

Cyclic, proteasome-mediated turnover of unliganded and liganded ERalpha on responsive promoters is an integral feature of estrogen signaling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417099

Decrease of estrogen receptor expression and associated ERE-dependent transcription in MCF-7 breast cancer cells after oligomycin treatment

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417099

Estrogen receptor phosphorylation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417099

Hyperactivation of MAPK induces loss of ERalpha expression in breast cancer cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417099

17β-Estradiol-induced cell proliferation requires estrogen receptor (ER) α monoubiquitination.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417099

17beta-Estradiol regulates the first steps of skeletal muscle cell differentiation via ER-alpha-mediated signals

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417099

Estrogen receptor regulation of carbonic anhydrase XII through a distal enhancer in breast cancer

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417099

The nutritional flavanone naringenin triggers antiestrogenic effects by regulating estrogen receptor alpha-palmitoylation

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417099

A conserved mechanism for steroid receptor translocation to the plasma membrane

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417099

Nature of functional estrogen receptors at the plasma membrane.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417099

S-palmitoylation modulates human estrogen receptor-alpha functions

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417099

Synergism between genomic and non genomic estrogen action mechanisms

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417099

Ligand-independent interactions of p160/steroid receptor coactivators and CREB-binding protein (CBP) with estrogen receptor-alpha: regulation by phosphorylation sites in the A/B region depends on other receptor domains.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417099

Evaluation of potential implication of membrane estrogen binding sites on ERE-dependent transcriptional activity and intracellular estrogen receptor-alpha regulation in MCF-7 breast cancer cells

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417099

Various phosphorylation pathways, depending on agonist and antagonist binding to endogenous estrogen receptor alpha (ERalpha), differentially affect ERalpha extractability, proteasome-mediated stability, and transcriptional activity in human breast

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22446104

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Evidence of an estrogen receptor form devoid of estrogen binding ability in MCF-7 cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22446104

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1210/ME.2011-1208

1 reference

28 July 2017

1 reference

28 July 2017

1 reference