Brd2 disruption in mice causes severe obesity without Type 2 diabetes (Q33642463)

28 July 2017

title

Brd2 disruption in mice causes severe obesity without Type 2 diabetes (English)

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28 July 2017

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4

Anna Belkina

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28 July 2017

Nathan K Lebrasseur

5

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Gerald V Denis

object named as

Gerald V Denis

6

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author name string

Fangnian Wang

1

1 reference

28 July 2017

Hongsheng Liu

2

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28 July 2017

Wanda P Blanton

3

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28 July 2017

language of work or name

English

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publication date

14 December 2009

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28 July 2017

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28 July 2017

volume

425

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28 July 2017

issue

1

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28 July 2017

page(s)

71-83

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The chromatin-targeting protein Brd2 is required for neural tube closure and embryogenesis

28 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

Double bromodomain-containing gene Brd2 is essential for embryonic development in mouse

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

Telomere homolog oligonucleotides induce apoptosis in malignant but not in normal lymphoid cells: mechanism and therapeutic potential

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

PRDM16 controls a brown fat/skeletal muscle switch

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

28 July 2018

Adiponectin: an update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

Adipose is a conserved dosage-sensitive antiobesity gene

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

Obesity-associated improvements in metabolic profile through expansion of adipose tissue

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

A double-bromodomain protein, FSH-S, activates the homeotic gene ultrabithorax through a critical promoter-proximal region

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

The double bromodomain-containing chromatin adaptor Brd4 and transcriptional regulation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

Inflammation and metabolic disorders

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

Genetic determinants of type 1 diabetes across populations

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

Selective deletion of Pten in pancreatic beta cells leads to increased islet mass and resistance to STZ-induced diabetes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

Identification of transcription complexes that contain the double bromodomain protein Brd2 and chromatin remodeling machines

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

Mediator and the mechanism of transcriptional activation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

Bromodomain analysis of Brd2-dependent transcriptional activation of cyclin A.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

Global prevalence of diabetes: estimates for the year 2000 and projections for 2030

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

A transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

Different sensitivities of bromodomain factors 1 and 2 to histone H4 acetylation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

Growth and early postimplantation defects in mice deficient for the bromodomain-containing protein Brd4.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

Genetic control of MHC class II expression

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

Bromodomain: an acetyl-lysine binding domain

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

Bromodomain motifs and "scaffolding"?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

You bet-cha: a novel family of transcriptional regulators

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

Duality in bromodomain-containing protein complexes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

RING3 kinase transactivates promoters of cell cycle regulatory genes through E2F

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

A bromodomain protein, MCAP, associates with mitotic chromosomes and affects G(2)-to-M transition

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

Transcriptional regulation of adipogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

Bromodomain factor 1 corresponds to a missing piece of yeast TFIID.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

The importance of the beta-cell in the pathogenesis of type 2 diabetes mellitus

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

Dissecting the regulatory circuitry of a eukaryotic genome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

Purification and biochemical heterogeneity of the mammalian SWI-SNF complex

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

Tumor necrosis factor-alpha- and hyperglycemia-induced insulin resistance. Evidence for different mechanisms and different effects on insulin signaling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

A novel, mitogen-activated nuclear kinase is related to a Drosophila developmental regulator

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

Bdf1, a yeast chromosomal protein required for sporulation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

Induction of fatty acid synthetase synthesis in differentiating 3T3-L1 preadipocytes.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

Genetic and molecular analysis of fs(1)h, a maternal effect homeotic gene in Drosophila.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

Cloning and molecular characterization of the trithorax locus of Drosophila melanogaster

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

Pancreatic islets of obese hyperglycemic mice (ob/ob).

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

Quantitation of adipose conversion and triglycerides by staining intracytoplasmic lipids with Oil red O.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

A homologue of the Drosophila female sterile homeotic (fsh) gene in the class II region of the human MHC.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

brahma: a regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SWI2

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

Global and societal implications of the diabetes epidemic

28 July 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090928

Insulin secretion in metabolically obese, but normal weight, and in metabolically healthy but obese individuals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090928

Crystal structure of the human BRD2 bromodomain: insights into dimerization and recognition of acetylated histone H4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090928

E mu-BRD2 transgenic mice develop B-cell lymphoma and leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090928

Type 2 diabetes-a matter of beta-cell life and death?

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090928

PPARγ Is Required for the Differentiation of Adipose Tissue In Vivo and In Vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090928

Adiponectinemia in visceral obesity: impact on glucose tolerance and plasma lipoprotein and lipid levels in men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090928

Obesity, Inflammation, and Insulin Resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090928

Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090928

RING3 is linked to the Xenopus major histocompatibility complex

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819394

DNA sequence and structure of the mouse RING3 gene: identification of variant RING3 transcripts

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19883376

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Energy in, energy out, and the effects of obesity-related genes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19883376

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1042/BJ20090928

1 reference

28 July 2017

1 reference

28 July 2017

1 reference