Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth (Q33758338)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15831479%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

title

Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth (English)

1 reference

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Maria Ciemerych-Litwinienko

10 January 2020

author

2

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10 January 2020

Ciemerych MA

3

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10 January 2020

Jake A Kushner

1

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Piotr Sicinski

8

object named as

Piotr Sicinski

1 reference

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10 January 2020

author name string

Ewa Sicinska

4

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10 January 2020

Lynn M Wartschow

5

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10 January 2020

Monica Teta

6

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10 January 2020

Simon Y Long

7

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10 January 2020

Morris F White

9

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10 January 2020

language of work or name

English

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publication date

1 May 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15831479%20AND%20SRC:MED&resulttype=core&format=json

Molecular and Cellular Biology

10 January 2020

published in

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10 January 2020

volume

25

1 reference

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10 January 2020

issue

9

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10 January 2020

page(s)

3752-3762

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15831479%20AND%20SRC:MED&resulttype=core&format=json

The pancreatic ductal epithelium serves as a potential pool of progenitor cells

10 January 2020

cites work

1 reference

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Beta cell replication is the primary mechanism for maintaining postnatal beta cell mass.

21 June 2018

1 reference

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Dysregulation of insulin receptor substrate 2 in beta cells and brain causes obesity and diabetes

21 June 2018

1 reference

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Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation

21 June 2018

1 reference

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Requirement for cyclin D3 in lymphocyte development and T cell leukemias

21 June 2018

1 reference

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Upregulation of insulin receptor substrate-2 in pancreatic beta cells prevents diabetes

21 June 2018

1 reference

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Cyclin E ablation in the mouse

21 June 2018

1 reference

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Genetic rescue of Cdk4 null mice restores pancreatic beta-cell proliferation but not homeostatic cell number

21 June 2018

1 reference

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Development of mice expressing a single D-type cyclin.

21 June 2018

1 reference

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Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

21 June 2018

1 reference

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IRS proteins and the common path to diabetes

21 June 2018

1 reference

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Pdx1 restores beta cell function in Irs2 knockout mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084308

beta-Cell death during progression to diabetes

21 June 2018

1 reference

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Diabetes mellitus and genetically programmed defects in beta-cell function

21 June 2018

1 reference

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Deletion of the p27Kip1 gene restores normal development in cyclin D1-deficient mice

21 June 2018

1 reference

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The Pezcoller lecture: cancer cell cycles revisited

21 June 2018

1 reference

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Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084308

Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia

21 June 2018

1 reference

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Disruption of IRS-2 causes type 2 diabetes in mice

21 June 2018

1 reference

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Cyclin D2 is an FSH-responsive gene involved in gonadal cell proliferation and oncogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084308

Cyclin D1 provides a link between development and oncogenesis in the retina and breast.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084308

Mice lacking cyclin D1 are small and show defects in eye and mammary gland development.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084308

Mouse development and cell proliferation in the absence of D-cyclins.

21 June 2018

1 reference

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Pancreatic islets from cyclin-dependent kinase 4/R24C (Cdk4) knockin mice have significantly increased beta cell mass and are physiologically functional, indicating that Cdk4 is a potential target for pancreatic beta cell mass regeneration in Type 1

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084308

Induction of beta-cell proliferation and retinoblastoma protein phosphorylation in rat and human islets using adenovirus-mediated transfer of cyclin-dependent kinase-4 and cyclin D1.

30 October 2018

1 reference

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Selective β-Cell Loss and α-Cell Expansion in Patients with Type 2 Diabetes Mellitus in Korea

30 October 2018

1 reference

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beta-cell turnover: its assessment and implications

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084308

Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084308

Deletion of Cdkn1b ameliorates hyperglycemia by maintaining compensatory hyperinsulinemia in diabetic mice

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15831479

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Signal transducer and activator of transcription 5 activation is sufficient to drive transcriptional induction of cyclin D2 gene and proliferation of rat pancreatic beta-cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15831479

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Rescue of Cyclin D1 Deficiency by Knockin Cyclin E

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15831479

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.25.9.3752-3762.2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15831479%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15831479%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

1 reference