Regulation of antigen receptor function by protein tyrosine kinases (Q33650619)

28 July 2017

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title

Regulation of antigen receptor function by protein tyrosine kinases (English)

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28 July 2017

3

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28 July 2017

Bubeck-Wardenburg J

1

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28 July 2017

Wong J

2

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28 July 2017

Pappu R

4

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28 July 2017

Fu C

5

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28 July 2017

Waksman G

6

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28 July 2017

Chan AC

7

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28 July 2017

publication date

1 January 1999

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Progress in Biophysics and Molecular Biology

28 July 2017

published in

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28 July 2017

volume

71

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28 July 2017

issue

3-4

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28 July 2017

page(s)

373-392

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Delayed thymocyte development induced by augmented expression of p56lck

28 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Thymic tumorigenesis induced by overexpression of p56lck

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Two GTPases, Cdc42 and Rac, bind directly to a protein implicated in the immunodeficiency disorder Wiskott-Aldrich syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Analysis of the interaction of ZAP-70 and syk protein-tyrosine kinases with the T-cell antigen receptor by plasmon resonance

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Phosphorylation of SLP-76 by the ZAP-70 protein-tyrosine kinase is required for T-cell receptor function

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

The role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Regulation of antigen receptor signal transduction by protein tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Syk tyrosine kinase required for mouse viability and B-cell development

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Catalytic domains of the LAR and CD45 protein tyrosine phosphatases from Escherichia coli expression systems: purification and characterization for specificity and mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

The Syk protein tyrosine kinase can function independently of CD45 or Lck in T cell antigen receptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Fetal hemorrhage and platelet dysfunction in SLP-76-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Signal transduction pathways that regulate the fate of B lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Role of Btk in B cell development and signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

p56lck interacts via its src homology 2 domain with the ZAP-70 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

syk kinase activation by a src kinase-initiated activation loop phosphorylation chain reaction

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Grap is a novel SH3-SH2-SH3 adaptor protein that couples tyrosine kinases to the Ras pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Blocked Ras activation in anergic CD4+ T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Dual role of the tyrosine activation motif of the Ig-alpha protein during signal transduction via the B cell antigen receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Identification of two tyrosine phosphoproteins, pp70 and pp68, which interact with phospholipase Cgamma, Grb2, and Vav after B cell antigen receptor activation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

BLNK: a central linker protein in B cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Structural basis for Syk tyrosine kinase ubiquity in signal transduction pathways revealed by the crystal structure of its regulatory SH2 domains bound to a dually phosphorylated ITAM peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Regulation of the pp72syk protein tyrosine kinase by platelet integrin alpha IIb beta 3

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Absence of ZAP-70 prevents signaling through the antigen receptor on peripheral blood T cells but not on thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Restoration of thymocyte development and function in zap-70-/- mice by the Syk protein tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

ZAP-70-dependent and -independent activation of Erk in Jurkat T cells. Differences in signaling induced by H2o2 and Cd3 cross-linking

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Rho GTPases and the actin cytoskeleton

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Fc epsilon RI aggregation induces tyrosine phosphorylation of a novel 72 kDa protein downstream of Syk

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

A Drosophila homolog of the Rac- and Cdc42-activated serine/threonine kinase PAK is a potential focal adhesion and focal complex protein that colocalizes with dynamic actin structures

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Molecular basis for interaction of the protein tyrosine kinase ZAP-70 with the T-cell receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Different nuclear signals are activated by the B cell receptor during positive versus negative signaling.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

SLP-76 is a substrate of the high affinity IgE receptor-stimulated protein tyrosine kinases in rat basophilic leukemia cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Crystal structure of the tyrosine kinase domain of the human insulin receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

ZAP-70 binding specificity to T cell receptor tyrosine-based activation motifs: the tandem SH2 domains of ZAP-70 bind distinct tyrosine-based activation motifs with varying affinity

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

BLNK required for coupling Syk to PLC gamma 2 and Rac1-JNK in B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

S-acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Fidelity of T cell activation through multistep T cell receptor zeta phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

The p21Rac/Cdc42-activated kinases (PAKs).

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Direct interaction of the Wiskott-Aldrich syndrome protein with the GTPase Cdc42

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Molecular mechanisms in B cell antigen receptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Differential intrinsic enzymatic activity of Syk and Zap-70 protein-tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Regulation of T-cell antigen receptor signalling by Syk tyrosine protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

A unique insert in the linker domain of Syk is necessary for its function in immunoreceptor signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Distinct intracellular localization of Lck and Fyn protein tyrosine kinases in human T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Blocked Signal Transduction to the ERK and JNK Protein Kinases in Anergic CD4+ T Cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Lack of SHPTP1 results in src-family kinase hyperactivation and thymocyte hyperresponsiveness

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Cytoskeletal polarization of T cells is regulated by an immunoreceptor tyrosine-based activation motif-dependent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Kinetic proofreading in T-cell receptor signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Three-dimensional segregation of supramolecular activation clusters in T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Molecular cloning of SLAP-130, an SLP-76-associated substrate of the T cell antigen receptor-stimulated protein tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Inhibition of T cell receptor expression and function in immature CD4+CD8+ cells by CD4

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Intrathymic signalling in immature CD4+ CD8+ thymocytes results in tyrosine phosphorylation of the T-cell receptor zeta chain

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Essential role for ZAP-70 in both positive and negative selection of thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

ZAP-70 is constitutively associated with tyrosine-phosphorylated TCR ζ in murine thymocytes and lymph node T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Constitutive tyrosine phosphorylation of the T-cell receptor (TCR) zeta subunit: regulation of TCR-associated protein tyrosine kinase activity by TCR zeta.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Differential regulation of activation-induced tyrosine phosphorylation and recruitment of SLP-76 to Vav by distinct isoforms of the CD45 protein-tyrosine phosphatase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Signaling through scaffold, anchoring, and adaptor proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Direct regulation of ZAP-70 by SHP-1 in T cell antigen receptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Regulation of Vav-SLP-76 binding by ZAP-70 and its relevance to TCR zeta/CD3 induction of interleukin-2

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Interaction of Shc with the zeta chain of the T cell receptor upon T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Antigen receptor tail clue.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Wiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domains

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Btk function in B cell development and response.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Direct binding and activation of receptor tyrosine kinases by collagen

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Cysteine3 of Src family protein tyrosine kinase determines palmitoylation and localization in caveolae

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Role of TCR zeta chain in T cell development and selection

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Human spleen tyrosine kinase p72Syk associates with the Src-family kinase p53/56Lyn and a 120-kDa phosphoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 production

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Wiskott-Aldrich syndrome protein-deficient mice reveal a role for WASP in T but not B cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

SH2 domain function is essential for the role of the Lck tyrosine kinase in T cell receptor signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

The role of a lymphoid-restricted, Grb2-like SH3-SH2-SH3 protein in T cell receptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

p95vav associates with tyrosine-phosphorylated SLP-76 in antigen-stimulated T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

X-linked thrombocytopenia and Wiskott-Aldrich syndrome are allelic diseases with mutations in the WASP gene

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Tyrosine kinases in activation of the MAP kinase cascade by G-protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Activating and Inhibitory Mutations in Adjacent Tyrosines in the Kinase Domain of ZAP-70

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Molecular cloning of the cDNA encoding pp36, a tyrosine-phosphorylated adaptor protein selectively expressed by T cells and natural killer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

SLP-65: a new signaling component in B lymphocytes which requires expression of the antigen receptor for phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

TCR activation of ZAP70 is impaired in CD4+CD8+ thymocytes as a consequence of intrathymic interactions that diminish available p56lck

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Regulation of T cell receptor expression in immature CD4+CD8+ thymocytes by p56lck tyrosine kinase: basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

A spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte development

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Reconstitution of T cell antigen receptor-induced Erk2 kinase activation in Lck-negative JCaM1 cells by Syk

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Genetic evidence of a role for Lck in T-cell receptor function independent or downstream of ZAP-70/Syk protein tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

A Nck-Pak1 signaling module is required for T-cell receptor-mediated activation of NFAT, but not of JNK

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Cloning of the cDNA for the deleted syk kinase homologous to ZAP-70 from human basophilic leukemia cell line (KU812).

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Evidence for involvement of two isoforms of Syk protein-tyrosine kinase in signal transduction through the high affinity IgE receptor on rat basophilic leukemia cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Distinct tyrosine phosphorylation sites in JAK3 kinase domain positively and negatively regulate its enzymatic activity

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

Defective T cell receptor signaling and CD8+ thymic selection in humans lacking zap-70 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6107%2898%2900060-1

7 January 2021

10.1016/S0079-6107(98)00060-1

Identifiers

DOI

1 reference

28 July 2017

1 reference