NMR and XAS reveal an inner-sphere metal binding site in the P4 helix of the metallo-ribozyme ribonuclease P. (Q33664471)

28 July 2017

title

NMR and XAS reveal an inner-sphere metal binding site in the P4 helix of the metallo-ribozyme ribonuclease P. (English)

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28 July 2017

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8

Carol A Fierke

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28 July 2017

Kristin S Koutmou

1

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28 July 2017

Anette Casiano-Negroni

2

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28 July 2017

Melissa M Getz

3

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28 July 2017

Samuel Pazicni

4

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28 July 2017

Andrew J Andrews

5

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28 July 2017

James E Penner-Hahn

6

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28 July 2017

Hashim M Al-Hashimi

7

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28 July 2017

language of work or name

English

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publication date

25 January 2010

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Proceedings of the National Academy of Sciences of the United States of America

28 July 2017

published in

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28 July 2017

volume

107

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28 July 2017

issue

6

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28 July 2017

page(s)

2479-2484

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Mapping metal-binding sites in the catalytic domain of bacterial RNase P RNA

28 July 2017

cites work

1 reference

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Synthetic antibodies for specific recognition and crystallization of structured RNA

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Importance of RNA-protein interactions in bacterial ribonuclease P structure and catalysis

21 June 2018

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Alternative roles for metal ions in enzyme catalysis and the implications for ribozyme chemistry

21 June 2018

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Structural plasticity and Mg2+ binding properties of RNase P P4 from combined analysis of NMR residual dipolar couplings and motionally decoupled spin relaxation

21 June 2018

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Studies on Escherichia coli RNase P RNA with Zn2+ as the catalytic cofactor

21 June 2018

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Metal ions and RNA folding: a highly charged topic with a dynamic future

21 June 2018

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Crystal structure of the leadzyme at 1.8 A resolution: metal ion binding and the implications for catalytic mechanism and allo site ion regulation

21 June 2018

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Recent insights into the structure and function of the ribonucleoprotein enzyme ribonuclease P.

21 June 2018

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Specific phosphorothioate substitutions probe the active site of Bacillus subtilis ribonuclease P.

21 June 2018

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Metal ion cooperativity in ribozyme cleavage of RNA.

21 June 2018

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Solution structure and metal-ion binding of the P4 element from bacterial RNase P RNA

21 June 2018

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Helix P4 is a divalent metal ion binding site in the conserved core of the ribonuclease P ribozyme

21 June 2018

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The 2 A structure of helix 6 of the human signal recognition particle RNA

21 June 2018

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The crystal structure of the dimerization initiation site of genomic HIV-1 RNA reveals an extended duplex with two adenine bulges

21 June 2018

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On the role of magnesium ions in RNA stability

21 June 2018

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Ribonuclease P: unity and diversity in a tRNA processing ribozyme

21 June 2018

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In vitro selection for altered divalent metal specificity in the RNase P RNA.

21 June 2018

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NMRPipe: a multidimensional spectral processing system based on UNIX pipes

21 June 2018

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Determination of the three-dimensional structure of margatoxin by 1H, 13C, 15N triple-resonance nuclear magnetic resonance spectroscopy

21 June 2018

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Synthesis of small RNAs using T7 RNA polymerase

21 June 2018

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Influence of metal ions on the ribonuclease P reaction. Distinguishing substrate binding from catalysis

21 June 2018

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Analysis of solvent nucleophile isotope effects: evidence for concerted mechanisms and nucleophilic activation by metal coordination in nonenzymatic and ribozyme-catalyzed phosphodiester hydrolysis

21 June 2018

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The P4 metal binding site in RNase P RNA affects active site metal affinity through substrate positioning

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.0906319107

Pb EXAFS studies on DNA quadruplexes: identification of metal ion binding site

21 January 2018

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Identification and characterization of a divalent metal ion-dependent cleavage site in the hammerhead ribozyme

21 January 2018

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Structural characterization of the zinc site in protein farnesyltransferase

21 January 2018

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A method for normalization of X-ray absorption spectra.

21 January 2018

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EXAFS studies of the zinc sites of UDP-(3-O-acyl)-N-acetylglucosamine deacetylase (LpxC).

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0906319107

G350 of Escherichia coli RNase P RNA contributes to Mg2+ binding near the active site of the enzyme

21 January 2018

1 reference

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Identification of phosphates involved in catalysis by the ribozyme RNase P RNA

30 October 2018

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The Limitations of X-ray Absorption Spectroscopy for Determining the Structure of Zinc Sites in Proteins. When Is a Tetrathiolate Not a Tetrathiolate?

30 October 2018

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https://api.crossref.org/works/10.1073%2FPNAS.0906319107

Crystal structure of the RNA component of bacterial ribonuclease P

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.0906319107

Integration of spin-state-selective excitation into 2D NMR correlation experiments with the heteronuclear ZQ/2Q pi rotations for 1JXH- resolved E.COSY-type measurements of heteronuclear coupling constants in proteins

21 January 2018

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12 December 2020

Multiple-scattering calculations of x-ray-absorption spectra

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12 December 2020

Magnesium ions are required by Bacillus subtilis ribonuclease P RNA for both binding and cleaving precursor tRNAAsp

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12 December 2020

Optimization of three-dimensional TROSY-type HCCH NMR correlation of aromatic (1)H-(13)C groups in proteins

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12 December 2020

The affinity of magnesium binding sites in the Bacillus subtilis RNase P x pre-tRNA complex is enhanced by the protein subunit

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12 December 2020

Metallobiochemistry of RNA. Co(NH3)6(3+) as a probe for Mg2+(aq) binding sites

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0906319107

1 reference

28 July 2017

0 references

1 reference

28 July 2017

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