Increased skeletal VEGF enhances beta-catenin activity and results in excessively ossified bones (Q33668117)

28 July 2017

Increased skeletal VEGF enhances beta-catenin activity and results in excessively ossified bones (English)

1 reference

28 July 2017

Steven Goossens

2

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Axel Behrens

object named as

Axel Behrens

17

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Andras Nagy

object named as

Andras Nagy

18

0 references

Peter Carmeliet

14

object named as

Peter Carmeliet

1 reference

28 July 2017

Christa Maes

1

1 reference

28 July 2017

Sonia Bartunkova

3

1 reference

28 July 2017

Benjamin Drogat

4

1 reference

28 July 2017

Lieve Coenegrachts

5

1 reference

28 July 2017

Ingrid Stockmans

6

1 reference

28 July 2017

Karen Moermans

7

1 reference

28 July 2017

Omar Nyabi

8

1 reference

28 July 2017

Katharina Haigh

9

1 reference

28 July 2017

Michael Naessens

10

1 reference

28 July 2017

Lieven Haenebalcke

11

1 reference

28 July 2017

Jan P Tuckermann

12

1 reference

28 July 2017

Marc Tjwa

13

1 reference

28 July 2017

Vice Mandic

15

1 reference

28 July 2017

Jean-Pierre David

16

1 reference

28 July 2017

Geert Carmeliet

19

1 reference

28 July 2017

Jody J Haigh

20

1 reference

28 July 2017

language of work or name

English

0 references

publication date

10 December 2009

1 reference

28 July 2017

1 reference

28 July 2017

29

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28 July 2017

2

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28 July 2017

424-441

1 reference

describes a project that uses

28 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2824461/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Canonical Wnt signaling regulates organ-specific assembly and differentiation of CNS vasculature

21 June 2018

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Wnt/beta-catenin signaling controls development of the blood-brain barrier

21 June 2018

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Suppressed NFAT-dependent VEGFR1 expression and constitutive VEGFR2 signaling in infantile hemangioma

21 June 2018

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Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of beta-catenin in mice

21 June 2018

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Nf2/merlin regulates hematopoietic stem cell behavior by altering microenvironmental architecture

21 June 2018

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The role of adherens junctions and VE-cadherin in the control of vascular permeability

21 June 2018

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Wnt and beyond Wnt: multiple mechanisms control the transcriptional property of beta-catenin

21 June 2018

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Bone formation during distraction osteogenesis is dependent on both VEGFR1 and VEGFR2 signaling.

21 June 2018

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VEGF: an essential mediator of both angiogenesis and endochondral ossification

21 June 2018

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Beta-catenin signaling plays a disparate role in different phases of fracture repair: implications for therapy to improve bone healing

21 June 2018

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A microenvironment-induced myeloproliferative syndrome caused by retinoic acid receptor gamma deficiency

21 June 2018

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PTK787/ZK 222584, a small molecule tyrosine kinase receptor inhibitor of vascular endothelial growth factor (VEGF), has modest activity in myelofibrosis with myeloid metaplasia

21 June 2018

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Inactivation of Pten in osteo-chondroprogenitor cells leads to epiphyseal growth plate abnormalities and skeletal overgrowth

21 June 2018

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Lifelong accumulation of bone in mice lacking Pten in osteoblasts

21 June 2018

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Wnt/beta-catenin signaling in development and disease

21 June 2018

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Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells

21 June 2018

1 reference

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VEGF receptor signalling - in control of vascular function

21 June 2018

1 reference

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Pathogenesis of myelofibrosis with myeloid metaplasia

21 June 2018

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Lrp5-independent activation of Wnt signaling by lithium chloride increases bone formation and bone mass in mice

21 June 2018

1 reference

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VEGF receptor 1 signaling is essential for osteoclast development and bone marrow formation in colony-stimulating factor 1-deficient mice

21 June 2018

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Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size

21 June 2018

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Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo

21 June 2018

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Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation

21 June 2018

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Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis

21 June 2018

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Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes

21 June 2018

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Conditional and inducible transgene expression in mice through the combinatorial use of Cre-mediated recombination and tetracycline induction.

21 June 2018

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Glycogen-Synthase Kinase3beta/beta-catenin axis promotes angiogenesis through activation of vascular endothelial growth factor signaling in endothelial cells.

21 June 2018

1 reference

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Sequential roles of Hedgehog and Wnt signaling in osteoblast development

21 June 2018

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Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1

21 June 2018

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Microenvironmental VEGF concentration, not total dose, determines a threshold between normal and aberrant angiogenesis

21 June 2018

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Hematopoiesis is severely altered in mice with an induced osteoblast deficiency

21 June 2018

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Soluble VEGF isoforms are essential for establishing epiphyseal vascularization and regulating chondrocyte development and survival

21 June 2018

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Angiogenesis and bone repair

21 June 2018

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Osteoblastic cells regulate the haematopoietic stem cell niche

21 June 2018

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The conditional inactivation of the beta-catenin gene in endothelial cells causes a defective vascular pattern and increased vascular fragility

21 June 2018

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Inhibitory phosphorylation of glycogen synthase kinase-3 (GSK-3) in response to lithium. Evidence for autoregulation of GSK-3.

21 June 2018

1 reference

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Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824461

Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824461

Skeletal defects in VEGF(120/120) mice reveal multiple roles for VEGF in skeletogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824461

Vascular endothelial growth factor and angiopoietin-1 stimulate postnatal hematopoiesis by recruitment of vasculogenic and hematopoietic stem cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824461

Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824461

Z/EG, a double reporter mouse line that expresses enhanced green fluorescent protein upon Cre-mediated excision

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824461

VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824461

Autocrine stimulation of VEGFR-2 activates human leukemic cell growth and migration

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824461

Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824461

VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824461

Generalized lacZ expression with the ROSA26 Cre reporter strain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824461

Wingless inactivates glycogen synthase kinase-3 via an intracellular signalling pathway which involves a protein kinase C.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824461

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824461

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824461

Temporal and spatial regulation of VEGF-A controls vascular patterning in the embryonic lung

21 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.361

Stimulation of osteoprotegerin production is responsible for osteosclerosis in mice overexpressing TPO.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.361

VEGF-A and PlGF-1 stimulate chemotactic migration of human mesenchymal progenitor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.361

Cortical and retinal defects caused by dosage-dependent reductions in VEGF-A paracrine signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.361

Vascular endothelial growth factor expression, beta-catenin tyrosine phosphorylation, and endothelial proliferative behavior: a pathway for transformation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.361

Regulation of angiogenesis by glycogen synthase kinase-3beta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.361

Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.361

Distinct roles for Hedgehog and canonical Wnt signaling in specification, differentiation and maintenance of osteoblast progenitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.361

Homologous up-regulation of KDR/Flk-1 receptor expression by vascular endothelial growth factor in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.361

Increased angiogenesis in chronic idiopathic myelofibrosis: vascular endothelial growth factor as a prominent angiogenic factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.361

Wnt signaling controls the phosphorylation status of beta-catenin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.361

Conditional inactivation of VEGF-A in areas of collagen2a1 expression results in embryonic lethality in the heterozygous state.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824461

Col2a1-directed expression of Cre recombinase in differentiating chondrocytes in transgenic mice.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824461

Ihh controls cartilage development by antagonizing Gli3, but requires additional effectors to regulate osteoblast and vascular development

30 October 2018

1 reference

12 December 2020

VEGF enhancement of osteoclast survival and bone resorption involves VEGF receptor-2 signaling and beta3-integrin

1 reference

12 December 2020

Osteosclerosis in advanced chronic idiopathic myelofibrosis is associated with endothelial overexpression of osteoprotegerin

1 reference

12 December 2020

The regulation of hematopoietic stem cell and progenitor mobilization by chemokine SDF-1

1 reference

12 December 2020

Vascular endothelial growth factor receptors in osteoclast differentiation and function

1 reference

12 December 2020

Serum levels, and bone marrow immunohistochemical expression of, vascular endothelial growth factor in patients with chronic myeloproliferative diseases

1 reference

12 December 2020

Identifiers

DOI

10.1038/EMBOJ.2009.361

1 reference

release_dv3yk7k4tfhtjij4vddyhbrqnm

28 July 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/dv3yk7k4tfhtjij4vddyhbrqnm

24 November 2022

mapped directly with Wikidata item

PMCID

2824461

1 reference

28 July 2017

1 reference