Whole genome profiling of spontaneous and chemically induced mutations in Toxoplasma gondii (Q33669290)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24885922%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

title

Whole genome profiling of spontaneous and chemically induced mutations in Toxoplasma gondii (English)

1 reference

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19 March 2020

main subject

Toxoplasma gondii

0 references

whole genome sequencing

1 reference

1

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19 March 2020

Bradley I Coleman

2

1 reference

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19 March 2020

Marc-Jan Gubbels

7

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19 March 2020

author name string

Brian Benenati

3

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19 March 2020

Kevin M Brown

4

1 reference

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19 March 2020

Ira J Blader

5

1 reference

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19 March 2020

Gabor T Marth

6

1 reference

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19 March 2020

language of work or name

English

0 references

publication date

10 May 2014

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19 March 2020

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19 March 2020

volume

15

1 reference

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19 March 2020

page(s)

354

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Forward genetic screening identifies a small molecule that blocks Toxoplasma gondii growth by inhibiting both host- and parasite-encoded kinases

19 March 2020

cites work

1 reference

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Identification of mutations in TgMAPK1 of Toxoplasma gondii conferring resistance to 1NM-PP1.

21 June 2018

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Genetic basis for phenotypic differences between different Toxoplasma gondii type I strains

21 June 2018

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Web-based visual analysis for high-throughput genomics

21 June 2018

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Mutation identification by direct comparison of whole-genome sequencing data from mutant and wild-type individuals using k-mers

21 June 2018

1 reference

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A forward genetic screen reveals that calcium-dependent protein kinase 3 regulates egress in Toxoplasma

21 June 2018

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The HU protein is important for apicoplast genome maintenance and inheritance in Toxoplasma gondii

21 June 2018

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Fast homozygosity mapping and identification of a zebrafish ENU-induced mutation by whole-genome sequencing

21 June 2018

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A genetic screen to isolate Toxoplasma gondii host-cell egress mutants

21 June 2018

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Mutagenesis as a tool in plant genetics, functional genomics, and breeding

21 June 2018

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A DOC2 protein identified by mutational profiling is essential for apicomplexan parasite exocytosis

21 June 2018

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Base excision repair apurinic/apyrimidinic endonucleases in apicomplexan parasite Toxoplasma gondii

21 June 2018

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Whole genome re-sequencing identifies a mutation in an ABC transporter (mdr2) in a Plasmodium chabaudi clone with altered susceptibility to antifolate drugs

21 June 2018

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A new dominant peroxiredoxin allele identified by whole-genome re-sequencing of random mutagenized yeast causes oxidant-resistance and premature aging

21 June 2018

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A strategy for direct mapping and identification of mutations by whole-genome sequencing

21 June 2018

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Analysis of multiple ethyl methanesulfonate-mutagenized Caenorhabditis elegans strains by whole-genome sequencing

21 June 2018

1 reference

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Whole-genome profiling of mutagenesis in Caenorhabditis elegans

21 June 2018

1 reference

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Whole-genome sequencing of a laboratory-evolved yeast strain

21 June 2018

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The impact of whole genome sequencing on model system genetics: get ready for the ride

21 June 2018

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Tracking the roots of cellulase hyperproduction by the fungus Trichoderma reesei using massively parallel DNA sequencing

21 June 2018

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Circos: an information aesthetic for comparative genomics

21 June 2018

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Efficient gene replacements in Toxoplasma gondii strains deficient for nonhomologous end joining

21 June 2018

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Comparing platforms for C. elegans mutant identification using high-throughput whole-genome sequencing

21 June 2018

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ENU mutagenesis, a way forward to understand gene function

21 June 2018

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Caenorhabditis elegans mutant allele identification by whole-genome sequencing

21 June 2018

1 reference

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Forward genetic analysis of the apicomplexan cell division cycle in Toxoplasma gondii

21 June 2018

1 reference

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ToxoDB: an integrated Toxoplasma gondii database resource

21 June 2018

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Cysteine protease inhibitors block Toxoplasma gondii microneme secretion and cell invasion

21 June 2018

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Mutagenesis strategies in zebrafish for identifying genes involved in development and disease

21 June 2018

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Genetic rescue of a Toxoplasma gondii conditional cell cycle mutant

21 June 2018

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A gene-driven ENU-based approach to generating an allelic series in any gene

21 June 2018

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21 June 2018

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Ionophore-resistant mutant of Toxoplasma gondii reveals involvement of a sodium/hydrogen exchanger in calcium regulation

21 June 2018

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A small-molecule approach to studying invasive mechanisms of Toxoplasma gondii

21 June 2018

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Toxoplasma gondii: the model apicomplexan.

21 June 2018

1 reference

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Spectrum of chemically induced mutations from a large-scale reverse-genetic screen in Arabidopsis.

21 June 2018

1 reference

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5-Fluorouracil: mechanisms of action and clinical strategies

21 June 2018

1 reference

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High-throughput growth assay for Toxoplasma gondii using yellow fluorescent protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035079

Large amounts of apicoplast nucleoid DNA and its segregation in Toxoplasma gondii

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035079

Isolation and characterization of a cold-sensitive attachment/invasion mutant of Toxoplasma gondii

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035079

Ionophore-resistant mutants of Toxoplasma gondii reveal host cell permeabilization as an early event in egress

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035079

Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035079

A plastid of probable green algal origin in Apicomplexan parasites.

21 June 2018

1 reference

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Insertional tagging, cloning, and expression of the Toxoplasma gondii hypoxanthine-xanthine-guanine phosphoribosyltransferase gene. Use as a selectable marker for stable transformation.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035079

Toxoplasma invasion of mammalian cells is powered by the actin cytoskeleton of the parasite

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035079

21 June 2018

1 reference

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Spectrum of mutations induced by methyl and ethyl methanesulfonate at the hprt locus of normal and tag expressing Chinese hamster fibroblasts

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035079

Insertional mutagenesis and marker rescue in a protozoan parasite: cloning of the uracil phosphoribosyltransferase locus from Toxoplasma gondii

21 June 2018

1 reference

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Molecular tools for genetic dissection of the protozoan parasite Toxoplasma gondii

21 June 2018

1 reference

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Nonrandom distribution of structural mutants in ethylnitrosourea-treated cultured human lymphoblastoid cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035079

Mutational specificity of ethyl methanesulfonate in excision-repair-proficient and -deficient strains of Drosophila melanogaster.

21 June 2018

1 reference

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Virulent strains of Toxoplasma gondii comprise a single clonal lineage

21 June 2018

1 reference

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Toxoplasma gondii: Isolation and preliminary characterization of temperature-sensitive mutants

21 June 2018

1 reference

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Quantitative Studies of the Mutagenesis of Toxoplasma gondii

21 June 2018

1 reference

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Toxoplasma gondii: The enzymic defect of a mutant resistant to 5-fluorodeoxyuridine

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035079

Toxoplasma gondii: Characterization of a mutant resistant to 5-fluorodeoxyuridine

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035079

Spectrum of ENU-induced mutations in phenotype-driven and gene-driven screens in the mouse.

21 June 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-15-354

Whole-genome sequencing and variant discovery in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-15-354

Rapid whole-genome mutational profiling using next-generation sequencing technologies

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-15-354

A general approach to single-nucleotide polymorphism discovery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-15-354

Estimation of the transition/transversion rate bias and species sampling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-15-354

A scan statistic for identifying chromosomal patterns of SNP association

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-15-354

Evidence of non-random mutation rates suggests an evolutionary risk management strategy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-15-354

21 January 2018

1 reference

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Whole-Genome Profiling of a Novel Mutagenesis Technique Using Proofreading-Deficient DNA Polymerase δ.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035079

Development of a screen to dissect Toxoplasma gondii egress

30 October 2018

1 reference

12 December 2020

Toxoplasma gondii: use of mutants to study the host-parasite relationship

1 reference

12 December 2020

Pyrimidine Synthesis by Intracellular Toxoplasma gondii

1 reference

12 December 2020

Rates of conservative and radical nonsynonymous nucleotide substitutions in mammalian nuclear genes

1 reference

12 December 2020

Arabinosyl nucleosides inhibit Toxoplasma gondii and allow the selection of resistant mutants

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12 December 2020

Identifiers

DOI

10.1186/1471-2164-15-354

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24885922%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

19 March 2020

1 reference

https://scigraph.springernature.com/pub.10.1186/1471-2164-15-354

9 September 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24885922%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

PubMed publication ID

24885922

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24885922%20AND%20SRC:MED&resulttype=core&format=json